Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Post Traumatic Stress Disorder: early-phase trial registry
110 of 265 indexed Post Traumatic Stress Disorder trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #37 of 28,707 conditions by registered trial count.
265 US clinical trials · 110 currently recruiting · #37 of 28,707 conditions by registered trial count
Post Traumatic Stress Disorder: 265 US clinical trials tracked, 110 recruiting.
Post Traumatic Stress Disorder is the subject of 265 registered US clinical trials on ClinicalTrials.gov, 110 of them currently open to new participants. 22 are in Phase 3-4 (later-stage) and 46 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 45 of these trials.
Enrollment posture brief
Registry condition post-traumatic-stress-disorder
OPEN 110 | RECR 42% | LATE 22 | EARLY 46 | RANK #37 | SPON 45
Volume-matched condition peers
Nearest open-share peer: Glaucoma (41% recruiting · 94 trials)
Post Traumatic Stress Disorder lists 110 open slots (42% of 265 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Post Traumatic Stress Disorder on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
-
Post Traumatic Stress Disorder is recruiting above its size-band peers.
110 of 265 indexed trials (41.5%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
-
One sponsor concentrates Post Traumatic Stress Disorder research.
VA Office of Research and Development accounts for 45 of 265 trials (17%). 130 distinct sponsors appear on at least one study for this condition label.
-
Typical Post Traumatic Stress Disorder enrolment sits around 81 participants.
Median target enrolment is 81 among the 263 trials that report a genuine target (sentinel values excluded). 149 of those (56.7%) plan for fewer than 100 participants.
-
Post Traumatic Stress Disorder research is mostly interventional.
250 interventional and 15 observational studies make up this index (94.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
265 total, page 4 of 6
PTSD Training for PCPs in a Virtual World
San Francisco Veterans Affairs Medical Center
NCT03898271
A Randomized Controlled Trial of Meditation Compared to Exposure Therapy and Education Control on PTSD in Veterans
United States Department of Defense
NCT01865123
Written Exposure Therapy for Posttraumatic Stress Disorder
Boston University
NCT01800773
A Comparison of CPT Versus ART Versus WL
University of Cincinnati
NCT03384706
Loving-Kindness Meditation for PTSD
VA Office of Research and Development
NCT01962714
Examination of Glutamate and mGluR5 in Psychiatric Disorders
Yale University
NCT02727972
Brief Peer Supported webSTAIR Compared to Enhanced Wait List
Palo Alto Veterans Institute for Research
NCT04286165
In-Home Exposure Therapy for Veterans With Post Traumatic Stress Disorder (PTSD)
Veterans Medical Research Foundation
NCT03110302
Quantifying the Efficacy and Role of Service Dogs for Military Veterans With PTSD
University of Arizona
NCT03245814
Efficacy Trial of Stress Check-Up
University of Washington
NCT03423394
The Efficacy of 90-Minute Versus 60-Minute Sessions of Prolonged Exposure for PTSD
University of Pennsylvania
NCT02720497
Clinical Trial to Evaluate the Safety and Efficacy of MeRT Treatment in Post-Traumatic Stress Disorder
Wave Neuroscience
NCT02990793
Effects of Early Abuse on Adult Intimate Relationships
University of Texas at Austin
NCT01803802
Treatment of Smoking Among Individuals With PTSD
University of Pennsylvania
NCT00937235
Virtual Reality (VR) Therapy for Post-Traumatic Stress Disorder (PTSD)
Office of Naval Research (ONR)
NCT00992953
Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy
Indiana University
NCT02213900
Cognitive Behavioral Treatments for Post-traumatic Stress Disorder (PTSD) Sleep Disturbance
US Department of Veterans Affairs
NCT00108628
Extinction of Fear Memories With Glucocorticoids in Veterans With PTSD
VA Office of Research and Development
NCT01090180
Adolescent Trauma Recovery and Stress Disorders Collaborative Care (ATRSCC) Model Program Trial
University of Washington
NCT00619255
PTSD Affect Labeling Study
University of California, Los Angeles
NCT05924399
An HIV Intervention for Black Men at Risk - The Enhanced Sexual Health Intervention for Men (ES-HIM)
University of California, Los Angeles
NCT01641146
Women Overcoming and Managing Adversity Now (WOMAN) Study
UConn Health
NCT01324765
Brain Function in Mentally Ill Adolescents
National Institute of Mental Health (NIMH)
NCT00025857
Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders
VA Office of Research and Development
NCT01947647
Behavioral Activation + Cognitive Processing Therapy for PTSD and Comorbid MDD
United States Naval Medical Center, San Diego
NCT02874131
A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP1)
Lykos Therapeutics
NCT03537014
Cannabidiol as a Treatment for AUD Comorbid With PTSD
NYU Langone Health
NCT03248167
Optimal Dose of Early Intervention to Prevent PTSD
Emory University
NCT01959620
Psychological Symptoms and Families of COVID-19 Patients
Rush University Medical Center
NCT04501445
Comparison of Videoconference and Face-to-Face Delivery of Cognitive Processing Therapy for Posttraumatic Stress Disorder
University of Wisconsin, Madison
NCT00941629
Mobile Self-Tracking of Mental Health
VA Office of Research and Development
NCT05023252
Treatment of Older Veterans With Chronic Posttraumatic Stress Disorder
US Department of Veterans Affairs
NCT00539279
Pilot Study Testing a Web-Based Moral Elevation Intervention for Veterans With PTSD and Moral Injury
VA Office of Research and Development
NCT03906240
Effectiveness of Cognitive, Exposure, and Skills Group Manualized Treatments in Operations Iraqi (OIF)/Operation Enduring Freedom (OEF) Female Veterans
New Mexico VA Healthcare System
NCT02069873
A Mobile Health Solution for Homework During CBT
University of South Florida
NCT04931199
Enhancement of PTSD Treatment With Computerized Executive Function Training
VA Office of Research and Development
NCT03260127
Telerehabilitation for OIF/OEF Returnees With Combat-Related Traumatic Brain Injury
VA Office of Research and Development
NCT00676182
Behavioral Activation for PTSD/Depression Treatment in OIF/OEF Veterans
VA Office of Research and Development
NCT00805532
Cognitive Training for PTSD
VA Office of Research and Development
NCT03316196
Remote Study of NightWare for PTSD With Nightmares
NightWare
NCT03934658
Primary-Care Based Mindfulness Intervention
Emory University
NCT03922581
Pilot Study of the Safety and Efficacy of Four Different Potencies of Smoked Marijuana in 76 Veterans With PTSD
Multidisciplinary Association for Psychedelic Studies
NCT02759185
Rehabilitation of Executive Functioning in Veterans With PTSD and Mild TBI
VA Office of Research and Development
NCT01921179
Cognitive Behavioral Therapy to Increase CPAP Adherence in Veterans With PTSD
VA Office of Research and Development
NCT02641496
Biological Signatures, Probiotic Among Those With mTBI and PTSD
VA Office of Research and Development
NCT02723344
Brief Cognitive Behavioral Treatment of Deployment-Related PTSD Symptoms in Primary Care Settings
The University of Texas Health Science Center at San Antonio
NCT02290639
Cognitively Augmented Behavioral Activation for Veterans With Comorbid TBI/PTSD
VA Office of Research and Development
NCT02391402
Improving Sleep to Reduce Risk for Substance Use Disorder
Florida State University
NCT03226132
Bright Light: An Adjunct Treatment for Combat Posttraumatic Stress Disorder (PTSD)
VA Office of Research and Development
NCT00701064
Writing Wrongs: Expressive Writing for Microaggressions
Auburn University
NCT06276725
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 15 |
| Phase 2 | 31 |
| Phase 3 | 11 |
| Phase 4 | 11 |
Top Sponsors
Named interventions
Most-linked intervention names on Post Traumatic Stress Disorder records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Post Traumatic Stress Disorder trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Post Traumatic Stress Disorder page
265 registered trials, 110 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 110 Post Traumatic Stress Disorder trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most Post Traumatic Stress Disorder trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Post Traumatic Stress Disorder condition card totals 265 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.