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NCT03316196 · ClinicalTrials.gov registry record · NA
Cognitive Training for PTSD
A NA study of Post Traumatic Stress Disorder, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- NA
- Development phase
- 81
- Enrollment target
- 1
- Study location
NCT03316196: Completed NA study of Post Traumatic Stress Disorder, sponsored by VA Office of Research and Development.
NCT03316196 is a NA study of Post Traumatic Stress Disorder that has completed, run by VA Office of Research and Development. The registered enrollment target is 81 participants, below the 664-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03316196, a NA study of Post Traumatic Stress Disorder, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- NA
- Development phase
- 81 participants
- Enrollment target
- 1
- Study location
Study Summary
Posttraumatic stress disorder (PTSD) is a chronic, disabling condition that occurs in a subgroup of individuals after experiencing traumatic stress, and is common in Veterans seeking mental health treatment at the VA. Although evidence-based psychosocial treatments exist for PTSD, a substantial portion of individuals do not fully respond to treatment. Thus, there is a clear need to continue researching novel interventions for PTSD in Veterans. Recently, new interventions for mental health disorders have utilized computerized cognitive training techniques in order to improve the functioning of cognitive systems and reduce symptoms. This type of intervention, often referred to as neurotherapeutics, may hold promise for PTSD as a method for ameliorating symptoms and improving cognition. Individuals with PTSD demonstrate difficulties with cognitive control functions, which appear to be causally implicated in symptoms of the disorder (e.g., intrusive trauma-related memories). To date the efficacy of neurotherapeutics for PTSD has been understudied in Veterans. The current proposal aims to bridge research on basic neurocognitive mechanisms of PTSD with intervention research by conducting a randomized controlled trial (RCT) of a cognitive control training program in 80 Veterans with PTSD. Veterans will complete computer-based training exercises designed to specifically target and improve aspects of cognitive control. Veterans will complete the program twice per week for eight weeks. Symptoms will be assessed before and after treatment, as well as at a two month follow up time point. The primary goal of the study is to examine the effect of the intervention on PTSD symptoms and cognitive deficits. Evaluating symptom change as a result of the intervention will provide critical data regarding the utility of this program as a PTSD treatment. If effective, this training program could serve as alternative treatment option for Veterans with PTSD, and could be translated into an
Primary Outcome
This semi-structured interview is designed to measure posttraumatic stress disorder diagnostic status as well as symptoms severity. Total scores range from 0 to 20 with higher scores indicating greater severity; change over time will be evaluated.
Conditions Studied
Interventions
- BEHAVIORAL COGENT COGNITIVE TRAINING
- BEHAVIORAL Non training computer condition
Study Locations (1)
California
- VA San Diego Healthcare System, San Diego, CA - San Diego
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 81 participants |
| Start Date | 2018-06-13 |
| Est. Completion | 2023-05-31 |
| Phase | NA |
What the finished NCT03316196 record still lists
NCT03316196 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 81 participants, a relatively small participant target, below the 664-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (88% lower).
The record links to 1 condition, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 2 interventions - of which COGENT COGNITIVE TRAINING is the first listed.
NCT03316196 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT03316196 about?
NCT03316196 is a clinical study titled "Cognitive Training for PTSD". Posttraumatic stress disorder (PTSD) is a chronic, disabling condition that occurs in a subgroup of individuals after experiencing traumatic stress, and is common in Veterans seeking mental health treatment at the VA. Although evidence-based psychosocial treatments exist for PTSD, a substantial port...
What is the current status of trial NCT03316196?
This trial is currently completed. It is a NA study. The enrollment target is 81 participants. The study started on 2018-06-13. Estimated completion is 2023-05-31.
What conditions does trial NCT03316196 study?
This clinical trial studies the following conditions: Post Traumatic Stress Disorder.
What interventions are being tested in trial NCT03316196?
The interventions under investigation include: COGENT COGNITIVE TRAINING (BEHAVIORAL), Non training computer condition (BEHAVIORAL).
Who is sponsoring clinical trial NCT03316196?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03316196 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03316196's enrollment target sits among peer trials
81 131st of 262 higher than 129 of 262 other Post Traumatic Stress Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Post Traumatic Stress Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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