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Post Traumatic Stress Disorder: early-phase trial registry
110 of 265 indexed Post Traumatic Stress Disorder trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #37 of 28,707 conditions by registered trial count.
265 US clinical trials · 110 currently recruiting · #37 of 28,707 conditions by registered trial count
Post Traumatic Stress Disorder: 265 US clinical trials tracked, 110 recruiting.
Post Traumatic Stress Disorder is the subject of 265 registered US clinical trials on ClinicalTrials.gov, 110 of them currently open to new participants. 22 are in Phase 3-4 (later-stage) and 46 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 45 of these trials.
Enrollment posture brief
Registry condition post-traumatic-stress-disorder
OPEN 110 | RECR 42% | LATE 22 | EARLY 46 | RANK #37 | SPON 45
Volume-matched condition peers
Nearest open-share peer: Glaucoma (41% recruiting · 94 trials)
Post Traumatic Stress Disorder lists 110 open slots (42% of 265 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Post Traumatic Stress Disorder on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Post Traumatic Stress Disorder is recruiting above its size-band peers.
110 of 265 indexed trials (41.5%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Post Traumatic Stress Disorder research.
VA Office of Research and Development accounts for 45 of 265 trials (17%). 130 distinct sponsors appear on at least one study for this condition label.
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Typical Post Traumatic Stress Disorder enrolment sits around 81 participants.
Median target enrolment is 81 among the 263 trials that report a genuine target (sentinel values excluded). 149 of those (56.7%) plan for fewer than 100 participants.
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Post Traumatic Stress Disorder research is mostly interventional.
250 interventional and 15 observational studies make up this index (94.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
265 total, page 5 of 6
Physiological Augmentation of Mindfulness Meditation
Emory University
NCT02754557
Online Coping Skills Counseling for Problem Gambling and Trauma
University of Windsor
NCT03145792
Stepped Care for Young Children After Trauma
University of South Florida
NCT01603563
Enhancing Cognitive Processing Therapy for Posttraumatic Stress Disorder Via Stellate Ganglion Block Treatment: A Pilot Trial
Rush University Medical Center
NCT05534126
Increasing Engagement in Evidence-Based PTSD Therapy for Primary Care Veterans
VA Office of Research and Development
NCT01984515
Bringing What Works to Youth in Corrections: A Trauma Intervention
University of Texas at Austin
NCT01560728
Brief Restructuring Intervention Following Trauma Exposure
University of Washington
NCT02808468
Primary Care Brief Mindfulness Training for Veterans With PTSD
Syracuse VA Medical Center
NCT03352011
Mindfulness-Based Stress Reduction and the Microbiome
Seattle Institute for Biomedical and Clinical Research
NCT01619384
Adjunctive Brief Behavioral Treatment of Insomnia (BBTI) for Sleep Intervention (SI)
VA Office of Research and Development
NCT02248675
Using mHealth to Improve Emotional Recovery After Pediatric Injury
Medical University of South Carolina
NCT04579198
EEG Biofeedback in the Treatment of Chronic Treatment-Resistant PTSD
Justice Resource Institute
NCT01259921
Written Exposure in Substance Treatment
Potomac Health Foundations
NCT06296940
An Efficient Treatment for Posttraumatic Injury for Firefighters
Palo Alto Veterans Institute for Research
NCT05950035
Effect of Mindfulness Meditation on Physiological Response to Unpredictable Stimuli
Georgetown University
NCT03206437
The Effects of the Safe and Sound Protocol on PTSD Symptoms and Anxiety
Indiana University
NCT04999852
Effect of Propranolol on Preventing Posttraumatic Stress Disorder
Massachusetts General Hospital
NCT00158262
Effects of a Short-term Exercise Intervention on Sleep in Women Exposed to Trauma: A Randomized Controlled Trial
University of Georgia
NCT05097352
Role of Substance P in Post-Traumatic Stress Disorder
National Institute of Mental Health (NIMH)
NCT00102102
rTMS for PTSD Comorbid With Major Depressive Disorder
Butler Hospital
NCT02273063
NightWare and Cardiovascular Health in Adults With PTSD
University of Colorado, Denver
NCT05365607
Measurement of Pituitary Volume and Hormonal Changes in Patients With Post-traumatic Stress Disorder
Cedars-Sinai Medical Center
NCT00815204
Combined Mirtazapine and SSRI Treatment of PTSD: A Placebo-Controlled Trial
Research Foundation for Mental Hygiene
NCT01178671
Improving Functional Outcomes of Veterans With PTSD and Tobacco Dependence
VA Office of Research and Development
NCT02576899
Mindful Self Compassion for Combat Deployed Veterans With Moral Injury and Co-occurring PTSD-SUD
VA Office of Research and Development
NCT03681288
An Open-Trial of Web-Prolonged Exposure (Web-PE) Among Active-Duty Military
University of Pennsylvania
NCT03337750
IOK Treatment Study
VA Office of Research and Development
NCT01605799
Yoga and Mantram for Chronic Pain and PTSD
VA Office of Research and Development
NCT03816007
A Pilot Exercise Study for PTSD in Women Veterans
North Texas Veterans Healthcare System
NCT01892033
Online Intervention to Promote Resilience to Traumatic Stress During Pregnancy
University of Illinois at Chicago
NCT04992767
Perceptions of MDMA-Assisted Therapy Among Veterans With PTSD
Albany Research Institute
NCT05895318
Frontline Clinician Psilocybin Study
University of Washington
NCT05163496
Written Exposure Therapy to Improve Recovery Among Sexual Assault Survivors
University of North Carolina, Chapel Hill
NCT06571513
Mobile Intervention for Veterans With PTSD and Anger
VA Office of Research and Development
NCT03733028
MGH Trauma-related Nightmares SDI Study
Massachusetts General Hospital
NCT05195684
Quetiapine Augmentation of PE Therapy for the Treatment of Co-occurring PTSD and Mild Traumatic Brain Injury
The University of Texas Health Science Center at San Antonio
NCT04280965
Maximizing Treatment Outcome in Post-Traumatic Stress Disorder (PTSD)
University of Texas at Austin
NCT01998100
Prolonged Exposure for Post Traumatic Stress Disorder (PTSD) With/Without Yohimbine
VA Office of Research and Development
NCT01031979
A Study of Sertraline to Prevent PTSD
Massachusetts General Hospital
NCT00182078
Transcranial Direct Current Stimulation (tDCS) in Human Subjects With PTSD Receiving an Exposure-based, Behavioral Therapy
The University of Texas Health Science Center at San Antonio
NCT05419999
Effect of Repetitive Transcranial Direct Current Stimulation (tDCS) on Chronic Pelvic Pain
Summa Health System
NCT00554320
Body-Oriented Therapy for Sexual Abuse Recovery
National Center for Complementary and Integrative Health (NCCIH)
NCT00097305
A Psychophysiologic Study of Weakening Traumatic Combat Memories With Post-Reactivation Propranolol
Massachusetts General Hospital
NCT00709735
MDMA-Assisted Psychotherapy in People With Posttraumatic Stress Disorder
Lykos Therapeutics
NCT00090064
Treating Co-Morbid Sleep Difficulties in Veterans With Posttraumatic Stress Disorder (PTSD): A Pilot Study
Durham VA Medical Center
NCT00734799
Treating Violence-related PTSD and Substance Risk in Low-income, Urban Adolescents
State University of New York at Buffalo
NCT03737383
Building Resilience After Childhood Emergencies (BRACE)
Case Western Reserve University
NCT02898883
The Effect of Nasal Continuous Positive Airway Pressure Treatment on PTSD Symptoms.
Northport Veterans Affairs Medical Center
NCT01512771
An Open Label Pilot Study of Adjunctive Asenapine for the Treatment of Posttraumatic Stress Disorder
Lori Davis, MD
NCT01587118
Piloting "Signs of Safety": A Deaf-Accessible Therapy Toolkit for Alcohol Use Disorder and Trauma
University of Massachusetts, Worcester
NCT03845985
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 15 |
| Phase 2 | 31 |
| Phase 3 | 11 |
| Phase 4 | 11 |
Top Sponsors
Named interventions
Most-linked intervention names on Post Traumatic Stress Disorder records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Post Traumatic Stress Disorder trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Post Traumatic Stress Disorder page
265 registered trials, 110 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 110 Post Traumatic Stress Disorder trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most Post Traumatic Stress Disorder trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Post Traumatic Stress Disorder condition card totals 265 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.