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NCT00539279 · ClinicalTrials.gov registry record · NA
Treatment of Older Veterans With Chronic Posttraumatic Stress Disorder
A NA study of Post Traumatic Stress Disorder and Combat Disorders, sponsored by US Department of Veterans Affairs.
- Completed
- Registry status
- NA
- Development phase
- 87
- Enrollment target
- 1
- Study location
NCT00539279: Completed NA study of Post Traumatic Stress Disorder and Combat Disorders, sponsored by US Department of Veterans Affairs.
NCT00539279 is a NA study of Post Traumatic Stress Disorder and Combat Disorders that has completed, run by US Department of Veterans Affairs. The registered enrollment target is 87 participants, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00539279, a NA study of Post Traumatic Stress Disorder and Combat Disorders, has completed, sponsored by US Department of Veterans Affairs.
- COMPLETED
- Registry status
- NA
- Development phase
- 87 participants
- Enrollment target
- 1
- Study location
Study Summary
This project represents the first randomized clinical trial of psychotherapy for older veterans with posttraumatic stress disorder (PTSD). It will compare relaxation training (RT) to prolonged exposure therapy (PE). The project will also examine whether cognitive impairment influences psychotherapy outcome. Primary hypotheses: (1) Subjects in the PE condition will have significantly less severe PTSD symptoms, depressive symptoms, and functional impairment than subjects in the RT condition at posttest; (2) Executive functioning will modify the response to both treatments, such that those with impaired executive functioning will demonstrate a smaller reduction in PTSD symptoms (representing less clinically significant change).
Primary Outcome
The PTSD Checklist is a self-report questionnaire about PTSD symptoms. The version used in this study is called the PCL-S, which denotes a specific traumatic event for subjects to respond to. There are 17 items, each with response categories from 1 to 5. Thus, the total score ranges from 17 to 85. Higher scores reflect higher levels of PTSD symptoms, and a score of 50 or above is commonly interpreted to designate clinically significant PTSD symptoms.
Conditions Studied
Interventions
- BEHAVIORAL Relaxation Training (RT)
- BEHAVIORAL Prolonged Exposure Therapy (PE)
Study Locations (1)
California
- VA San Diego Healthcare System, San Diego - San Diego
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 87 participants |
| Start Date | 2009-03 |
| Est. Completion | 2013-03 |
| Phase | NA |
What the finished NCT00539279 record still lists
NCT00539279 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 87 participants, a relatively small participant target, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (87% lower).
The record links to 2 conditions, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 2 interventions - of which Relaxation Training (RT) is the first listed.
NCT00539279 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT00539279 about?
NCT00539279 is a clinical study titled "Treatment of Older Veterans With Chronic Posttraumatic Stress Disorder". This project represents the first randomized clinical trial of psychotherapy for older veterans with posttraumatic stress disorder (PTSD). It will compare relaxation training (RT) to prolonged exposure therapy (PE). The project will also examine whether cognitive impairment influences psychotherapy ...
What is the current status of trial NCT00539279?
This trial is currently completed. It is a NA study. The enrollment target is 87 participants. The study started on 2009-03. Estimated completion is 2013-03.
What conditions does trial NCT00539279 study?
This clinical trial studies the following conditions: Post Traumatic Stress Disorder, Combat Disorders.
What interventions are being tested in trial NCT00539279?
The interventions under investigation include: Relaxation Training (RT) (BEHAVIORAL), Prolonged Exposure Therapy (PE) (BEHAVIORAL).
Who is sponsoring clinical trial NCT00539279?
This trial is sponsored by US Department of Veterans Affairs, which has 632 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00539279 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00539279's enrollment target sits among peer trials
87 123rd of 262 higher than 137 of 262 other Post Traumatic Stress Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Post Traumatic Stress Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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