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NCT02720497 · ClinicalTrials.gov registry record · NA
The Efficacy of 90-Minute Versus 60-Minute Sessions of Prolonged Exposure for PTSD
A NA study of Post Traumatic Stress Disorder and Combat Disorder, sponsored by University of Pennsylvania.
- Completed
- Registry status
- NA
- Development phase
- 160
- Enrollment target
- 1
- Study location
NCT02720497: Completed NA study of Post Traumatic Stress Disorder and Combat Disorder, sponsored by University of Pennsylvania.
NCT02720497 is a NA study of Post Traumatic Stress Disorder and Combat Disorder that has completed, run by University of Pennsylvania. The registered enrollment target is 160 participants, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02720497, a NA study of Post Traumatic Stress Disorder and Combat Disorder, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- NA
- Development phase
- 160 participants
- Enrollment target
- 1
- Study location
Study Summary
Objectives and Rationale: With up to 20% of U.S. service members returning from Iraq and Afghanistan with PTSD symptoms, a critical need exists for treatments that are both effective and efficient, enabling the greatest number possible to be treated to remission. As a highly efficacious treatment and the one with the most scientific support, Prolonged Exposure (PE) is recommended by the Institute of Medicine and being rolled out by the Departments of Defense and Veterans Affairs to help heal our war fighters' psychological wounds. A major barrier to that roll-out, however, is that PE is typically delivered in 90-minute sessions. This is difficult for military mental health providers, who because of large patient loads and pressure to see as many patients per day as possible, limit therapy sessions to 60 minutes. The primary aim of this randomized clinical trial is to determine whether PE sessions can be reduced to 60 minutes without compromising the treatment's high success rate. Preliminary evidence suggests that patients may greatly benefit from PE even when the time spent recalling and recounting the trauma memories during sessions (a key procedure called imaginal exposure) is shortened to fit into a 60-minute session. To test this hypothesis, the trial will enroll 160 San Antonio-area active duty service members who will be randomly assigned to receive PE treatment with 60- or 90-minute sessions. In an additional effort to learn more about how PE helps patients recover - and thereby gain insights to further enhance treatment benefit - the study investigators will examine what causes reductions in PTSD symptoms during PE by examining self-reported and physiological markers (e.g., heart rate reactivity) between the two treatment groups. Research Applicability and Impact: If PE can be shown to maintain high success rates with shorter sessions, more military clinicians could offer this powerful therapy, as it would fit within time constraints of their heavy workloa
Conditions Studied
Interventions
- BEHAVIORAL 60-minute Prolonged Exposure Therapy
- BEHAVIORAL 90-minute Prolonged Exposure Therapy
Study Locations (1)
South Carolina
- Medical University of South Carolina - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 160 participants |
| Start Date | 2013-09 |
| Est. Completion | 2021-03 |
| Phase | NA |
What the finished NCT02720497 record still lists
NCT02720497 is an interventional study that assigns participants to a tested intervention. The registered 160 participants enrollment target is mid-sized for trials with a published cap, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (76% lower).
The record links to 2 conditions, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 2 interventions - of which 60-minute Prolonged Exposure Therapy is the first listed.
NCT02720497 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT02720497 about?
NCT02720497 is a clinical study titled "The Efficacy of 90-Minute Versus 60-Minute Sessions of Prolonged Exposure for PTSD". Objectives and Rationale: With up to 20% of U.S. service members returning from Iraq and Afghanistan with PTSD symptoms, a critical need exists for treatments that are both effective and efficient, enabling the greatest number possible to be treated to remission. As a highly efficacious treatment an...
What is the current status of trial NCT02720497?
This trial is currently completed. It is a NA study. The enrollment target is 160 participants. The study started on 2013-09. Estimated completion is 2021-03.
What conditions does trial NCT02720497 study?
This clinical trial studies the following conditions: Post Traumatic Stress Disorder, Combat Disorder.
What interventions are being tested in trial NCT02720497?
The interventions under investigation include: 60-minute Prolonged Exposure Therapy (BEHAVIORAL), 90-minute Prolonged Exposure Therapy (BEHAVIORAL).
Who is sponsoring clinical trial NCT02720497?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02720497 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT02720497's enrollment target sits among peer trials
160 75th of 262 higher than 188 of 262 other Post Traumatic Stress Disorder trials
participants (enrollment target), bucketed by value
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