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NCT05924399 · ClinicalTrials.gov registry record · NA
PTSD Affect Labeling Study
A NA study of Post Traumatic Stress Disorder and Post-Traumatic Stress Disorder, Chronic, sponsored by University of California, Los Angeles.
- Completed
- Registry status
- NA
- Development phase
- 119
- Enrollment target
- 1
- Study location
NCT05924399: Completed NA study of Post Traumatic Stress Disorder and Post-Traumatic Stress Disorder, Chronic, sponsored by University of California, Los Angeles.
NCT05924399 is a NA study of Post Traumatic Stress Disorder and Post-Traumatic Stress Disorder, Chronic that has completed, run by University of California, Los Angeles. The registered enrollment target is 119 participants, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05924399, a NA study of Post Traumatic Stress Disorder and Post-Traumatic Stress Disorder, Chronic, has completed, sponsored by University of California, Los Angeles.
- COMPLETED
- Registry status
- NA
- Development phase
- 119 participants
- Enrollment target
- 1
- Study location
Study Summary
The overall goal of this study is to use fMRI and psychophysiological measures to investigate a novel strategy involving "Affect Labeling" for improving emotion regulation in PTSD that could lead to a new treatment regimen for PTSD. Our project has two specific aims. First, the investigators aim to identify a novel neural target for possible PTSD intervention by verifying that RVLPFC-based inhibitory processing is impaired in PTSD. Second, the investigators will examine whether repeated practice with a simple cognitive-emotional task that requires inhibitory processing, namely, affect labeling, can strengthen the RVLPFC's ability to down-regulate emotional responses and physiological reactivity in PTSD and thereby form the basis of a novel treatment strategy to be developed in future studies. Secondary objectives are to examine the extent to which RVLPFC-based inhibitory impairments in PTSD are specific to trauma-relevant emotional processing (i.e., trauma-related distress) or extend to other types of inhibitory regulation in general, which would have implications for the future study of inhibitory-enhancement-based interventions for PTSD.
Primary Outcome
The PANAS is a widely used measure comprising 20-items assessing activated forms of Positive Affect and Negative Affect using 5-point scales (1 = very slightly/not at all, 5 = extremely). Higher scores on each subscale (positive affect and negative affect) reflect higher levels of positive and negative affect, respectively.
Conditions Studied
Interventions
- BEHAVIORAL Affect Labeling Training
Study Locations (1)
California
- University of California, Los Angeles - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 119 participants |
| Start Date | 2014-08-05 |
| Est. Completion | 2015-10-09 |
| Phase | NA |
What the finished NCT05924399 record still lists
NCT05924399 is an interventional study that assigns participants to a tested intervention. The registered 119 participants enrollment target is mid-sized for trials with a published cap, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (82% lower).
The record links to 2 conditions, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 1 intervention - of which Affect Labeling Training is the first listed.
NCT05924399 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05924399 about?
NCT05924399 is a clinical study titled "PTSD Affect Labeling Study". The overall goal of this study is to use fMRI and psychophysiological measures to investigate a novel strategy involving "Affect Labeling" for improving emotion regulation in PTSD that could lead to a new treatment regimen for PTSD. Our project has two specific aims. First, the investigators aim to...
What is the current status of trial NCT05924399?
This trial is currently completed. It is a NA study. The enrollment target is 119 participants. The study started on 2014-08-05. Estimated completion is 2015-10-09.
What conditions does trial NCT05924399 study?
This clinical trial studies the following conditions: Post Traumatic Stress Disorder, Post-Traumatic Stress Disorder, Chronic.
What interventions are being tested in trial NCT05924399?
The interventions under investigation include: Affect Labeling Training (BEHAVIORAL).
Who is sponsoring clinical trial NCT05924399?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05924399 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05924399's enrollment target sits among peer trials
119 106th of 262 higher than 157 of 262 other Post Traumatic Stress Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Post Traumatic Stress Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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