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ClinicalTrials.gov 22 recruiting now early-phase tilt

Idiopathic Pulmonary Fibrosis: early-phase trial registry

22 of 52 indexed Idiopathic Pulmonary Fibrosis trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #271 of 28,707 conditions by registered trial count.

52 US clinical trials · 22 currently recruiting · #271 of 28,707 conditions by registered trial count

Idiopathic Pulmonary Fibrosis: 52 US clinical trials tracked, 22 recruiting.

Idiopathic Pulmonary Fibrosis is the subject of 52 registered US clinical trials on ClinicalTrials.gov, 22 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 33 in Phase 1-2 (earlier-stage). The most active sponsor is Boehringer Ingelheim, running 5 of these trials.

Enrollment posture brief

Registry condition idiopathic-pulmonary-fibrosis

OPEN 22 | RECR 42% | LATE 5 | EARLY 33 | RANK #271 | SPON 5

Nearest open-share peer: Metastatic Pancreatic Cancer (42% recruiting · 33 trials)

Pediatric Cancer59.6%Hidradenitis Suppurativa54.7%Idiopathic Pulmonary Fib (th…42%Depressive Disorder, Major26.4%Congestive Heart Failure15.4%
Open-enrollment share among volume-matched conditions near Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis lists 22 open slots (42% of 52 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Idiopathic Pulmonary Fibrosis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Idiopathic Pulmonary Fibrosis is recruiting above its size-band peers.

    22 of 52 indexed trials (42.3%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Idiopathic Pulmonary Fibrosis trials is spread across many organizations.

    Boehringer Ingelheim accounts for 5 of 52 trials (9.6%). 37 distinct sponsors appear on at least one study for this condition label.

  3. Typical Idiopathic Pulmonary Fibrosis enrolment sits around 61 participants.

    Median target enrolment is 61 among the 52 trials that report a genuine target (sentinel values excluded). 31 of those (59.6%) plan for fewer than 100 participants.

  4. Idiopathic Pulmonary Fibrosis research is mostly interventional.

    41 interventional and 11 observational studies make up this index (78.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 113Phase 220Phase 34Phase 41

Open and recent trials

52 total, page 1 of 2

RECRUITING 10,000 participants

Pulmonary Fibrosis Foundation Community Registry

Pulmonary Fibrosis Foundation

NCT05382572

RECRUITING 4,000 participants

A Study of the Natural Progression of Interstitial Lung Disease (ILD)

University of Chicago

NCT00470327

RECRUITING Phase 3 1,700 participants

A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast

Boehringer Ingelheim

NCT06238622

RECRUITING 1,000 participants

Interstitial Lung Disease Research Unit Biobank

University of Kansas Medical Center

NCT05392881

RECRUITING 750 participants

Mechanisms of Familial Pulmonary Fibrosis

Vanderbilt University Medical Center

NCT03437486

RECRUITING 500 participants

Genomic and Proteomic Analysis of Disease Progression in Idiopathic Pulmonary Fibrosis (IPF)

University of Pittsburgh

NCT00373841

RECRUITING Phase 2 165 participants

Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Idiopathic Pulmonary Fibrosis

AbbVie

NCT07230288

RECRUITING Phase 2 164 participants

WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Mediar Therapeutics

NCT06967805

RECRUITING 160 participants

The Role of Quantitative CT and Radiomic Biomarkers for Precision Medicine in Pulmonary Fibrosis

University of Virginia

NCT06323876

RECRUITING Phase 2 150 participants

A Phase 2 Study of CAL101 in Patients With Idiopathic Pulmonary Fibrosis

Calluna Pharma AS

NCT06736990

RECRUITING Phase 2 128 participants

Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Cumberland Pharmaceuticals

NCT05571059

RECRUITING Phase 2 102 participants

Clinical Trial to Evaluate the Safety and Efficacy of DWN12088 in Patients With IPF

Daewoong Pharmaceutical Co.

NCT05389215

RECRUITING Phase 1 72 participants

A Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GNS-3545 in Healthy Participants

Genosco

NCT07225296

RECRUITING Phase 2 71 participants

A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) With or Without Standard Treatment

Boehringer Ingelheim

NCT07036523

RECRUITING Phase 2 60 participants

Zinc and Nicotinamide Riboside for Idiopathic Pulmonary Fibrosis

Cedars-Sinai Medical Center

NCT06567717

RECRUITING Phase 2 37 participants

H01 in Adults With Interstitial Lung Disease (The SOLIS Study)

National Institute of Environmental Health Sciences (NIEHS)

NCT06325696

RECRUITING Phase 2 20 participants

A Study in People With Idiopathic Pulmonary Fibrosis to Test Whether Pirfenidone Influences the Amount of BI 1015550 in the Blood

Boehringer Ingelheim

NCT06241560

RECRUITING Phase 1 15 participants

Dose-Escalation Study of Artesunate Patients With IPF

Joseph C. Wu

NCT05988463

RECRUITING Phase 1 10 participants

NAL ER IPF Respiratory Function and Safety Study

Trevi Therapeutics

NCT07036029

RECRUITING Phase 1 10 participants

Molecular Imaging Probes to Inform Heterogeneity in Idiopathic Pulmonary Fibrosis

University of Alabama at Birmingham

NCT04362644

RECRUITING Phase 1 8 participants

Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure

Paul Szabolcs

NCT03500731

RECRUITING Early Phase 1 6 participants

Hyperpolarized Xenon-129 MRI in Idiopathic Pulmonary Fibrosis

University of Virginia

NCT06853145

ACTIVE NOT RECRUITING Phase 3 1,255 participants

A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Idiopathic Pulmonary Fibrosis

Bristol-Myers Squibb

NCT06003426

ACTIVE NOT RECRUITING 1,000 participants

PaTH Clinical Data Research Network (CDRN) Idiopathic Pulmonary Fibrosis (IPF) Clinician Patient Partnership Cohort

University of Pittsburgh

NCT02407431

ACTIVE NOT RECRUITING 450 participants

Detection of Early Idiopathic Pulmonary Fibrosis

Temple University

NCT03457935

ACTIVE NOT RECRUITING Phase 2 240 participants

LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)

PureTech

NCT05321420

ACTIVE NOT RECRUITING NA 61 participants

Yoga Effect on Quality of Life Study Among Patients with Idiopathic Pulmonary Fibrosis

University of Washington

NCT02848625

ACTIVE NOT RECRUITING Phase 2 60 participants

Xenon MRI and Progressive ILD

Duke University

NCT05241275

ACTIVE NOT RECRUITING Phase 1 50 participants

Study of Oral Epigallocatechin-3-gallate (EGCG) in IPF Patients

Hal Chapman

NCT05195918

ACTIVE NOT RECRUITING Phase 2 34 participants

Genentech Xenon MRI Idiopathic Pulmonary Fibrosis

Duke University

NCT04071769

ACTIVE NOT RECRUITING Phase 1 24 participants

Atezolizumab for Idiopathic Pulmonary Fibrosis

Cedars-Sinai Medical Center

NCT05515627

ACTIVE NOT RECRUITING Phase 1 22 participants

Collagen-targeted Positron Emission Tomography (PET) Imaging for Assessment of EGCG Effect

Hal Chapman

NCT06265532

COMPLETED 13,264 participants

A Study Based on Medical Records That Looks at the Characteristics of Idiopathic Pulmonary Fibrosis Patients Grouped by the Type of Medication They Are Taking

Boehringer Ingelheim

NCT03958071

COMPLETED Phase 3 1,177 participants

A Study to Find Out Whether BI 1015550 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF)

Boehringer Ingelheim

NCT05321069

COMPLETED Phase 3 435 participants

Three-Arm Study of the Safety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis

Genentech

NCT00287716

COMPLETED Phase 2 325 participants

Safety and Efficacy of a Lysophosphatidic Acid Receptor Antagonist in Idiopathic Pulmonary Fibrosis

Bristol-Myers Squibb

NCT01766817

COMPLETED Phase 2 178 participants

Macitentan Use in an Idiopathic Pulmonary Fibrosis Clinical Study

Actelion

NCT00903331

COMPLETED Phase 4 89 participants

Safety and Tolerability Study of Pirfenidone in Combination With Nintedanib in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Hoffmann-La Roche

NCT02598193

COMPLETED 63 participants

Characterization of Apolipoprotein A-I Pathways in Idiopathic Pulmonary Fibrosis

National Heart, Lung, and Blood Institute (NHLBI)

NCT02315586

COMPLETED Phase 2 58 participants

GKT137831 in IPF Patients with Idiopathic Pulmonary Fibrosis

University of Alabama at Birmingham

NCT03865927

COMPLETED Phase 2 58 participants

Study of Inhaled Carbon Monoxide to Treat Idiopathic Pulmonary Fibrosis

Brigham and Women's Hospital

NCT01214187

COMPLETED Phase 1 56 participants

A Safety, Tolerability, and Pharmacokinetic Study of NIP292 in Healthy Normal Subjects

The National Institutes of Pharmaceutical R&D Co. Ltd, China

NCT04720443

COMPLETED Phase 2 52 participants

SD, IL-13 Production Rate in IPF

Novartis Pharmaceuticals

NCT00532233

COMPLETED Phase 2 44 participants

Zileuton for the Treatment of Idiopathic Pulmonary Fibrosis

University of Michigan

NCT00262405

COMPLETED NA 43 participants

Palliative Care Planner (PCplanner)

Duke University

NCT05095363

COMPLETED Early Phase 1 35 participants

Fibroblast Specific Inhibition of LOXL2 and TGFbeta1 Signaling in Patients With Pulmonary Fibrosis.

Hal Chapman

NCT03928847

COMPLETED NA 32 participants

IPF mHealth Exercise Study

University of Washington

NCT04838275

COMPLETED Phase 1 32 participants

Randomized, Crossover, Multi-Dose Pharmacokinetics of EXCL-100 Pirfenidone-Sustained Release Tablet and Esbriet in Healthy Volunteers

Excalibur Pharmaceuticals

NCT05428150

COMPLETED Phase 1 21 participants

A Study of Oral Vismodegib in Combination With Pirfenidone in Participants With Idiopathic Pulmonary Fibrosis

Hoffmann-La Roche

NCT02648048

COMPLETED 20 participants

Microaspiration in Pulmonary Fibrosis

University of California, San Francisco

NCT01150591

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Phase Distribution

PhaseTrial count
Phase 1 13
Phase 2 20
Phase 3 4
Phase 4 1

Named interventions

Most-linked intervention names on Idiopathic Pulmonary Fibrosis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
10 trials
Pirfenidone Drug
6 trials
Nintedanib Drug
2 trials
BI 1015550 Drug
2 trials
NIP292 tablet Drug
1 trials
EXCL-100, 600 MG Oral Tablet Drug
1 trials
Esbriet 267 MG Oral Capsule Drug
1 trials
azathioprine/prednisone Drug
1 trials

US sites by state

Facility locations filed on Idiopathic Pulmonary Fibrosis trials. A trial with sites in several states counts in each.

California 22 trials
Pennsylvania 15 trials
North Carolina 13 trials
Kansas 11 trials
Illinois 11 trials
Florida 11 trials
Alabama 11 trials
Michigan 9 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Idiopathic Pulmonary Fibrosis page

52 registered trials, 22 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 22 Idiopathic Pulmonary Fibrosis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Boehringer Ingelheim sponsors the most Idiopathic Pulmonary Fibrosis trials on record, review their full trial history before evaluating a specific study. See Boehringer Ingelheim's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Idiopathic Pulmonary Fibrosis condition card totals 52 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.