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2026 data Public-data reference. official source

Idiopathic Pulmonary Fibrosis

Open-data reference.

52 US clinical trials · 22 currently recruiting

Active & Recent Trials

RECRUITING 10,000 participants

Pulmonary Fibrosis Foundation Community Registry

Pulmonary Fibrosis Foundation

NCT05382572

RECRUITING 4,000 participants

A Study of the Natural Progression of Interstitial Lung Disease (ILD)

University of Chicago

NCT00470327

RECRUITING Phase 3 1,700 participants

A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast

Boehringer Ingelheim

NCT06238622

RECRUITING 1,000 participants

Interstitial Lung Disease Research Unit Biobank

University of Kansas Medical Center

NCT05392881

RECRUITING 750 participants

Mechanisms of Familial Pulmonary Fibrosis

Vanderbilt University Medical Center

NCT03437486

RECRUITING 500 participants

Genomic and Proteomic Analysis of Disease Progression in Idiopathic Pulmonary Fibrosis (IPF)

University of Pittsburgh

NCT00373841

RECRUITING Phase 2 165 participants

Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Idiopathic Pulmonary Fibrosis

AbbVie

NCT07230288

RECRUITING Phase 2 164 participants

WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Mediar Therapeutics

NCT06967805

RECRUITING 160 participants

The Role of Quantitative CT and Radiomic Biomarkers for Precision Medicine in Pulmonary Fibrosis

University of Virginia

NCT06323876

RECRUITING Phase 2 150 participants

A Phase 2 Study of CAL101 in Patients With Idiopathic Pulmonary Fibrosis

Calluna Pharma AS

NCT06736990

RECRUITING Phase 2 128 participants

Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Cumberland Pharmaceuticals

NCT05571059

RECRUITING Phase 2 102 participants

Clinical Trial to Evaluate the Safety and Efficacy of DWN12088 in Patients With IPF

Daewoong Pharmaceutical Co.

NCT05389215

RECRUITING Phase 1 72 participants

A Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GNS-3545 in Healthy Participants

Genosco

NCT07225296

RECRUITING Phase 2 71 participants

A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) With or Without Standard Treatment

Boehringer Ingelheim

NCT07036523

RECRUITING Phase 2 60 participants

Zinc and Nicotinamide Riboside for Idiopathic Pulmonary Fibrosis

Cedars-Sinai Medical Center

NCT06567717

RECRUITING Phase 2 37 participants

H01 in Adults With Interstitial Lung Disease (The SOLIS Study)

National Institute of Environmental Health Sciences (NIEHS)

NCT06325696

RECRUITING Phase 2 20 participants

A Study in People With Idiopathic Pulmonary Fibrosis to Test Whether Pirfenidone Influences the Amount of BI 1015550 in the Blood

Boehringer Ingelheim

NCT06241560

RECRUITING Phase 1 15 participants

Dose-Escalation Study of Artesunate Patients With IPF

Joseph C. Wu

NCT05988463

RECRUITING Phase 1 10 participants

NAL ER IPF Respiratory Function and Safety Study

Trevi Therapeutics

NCT07036029

RECRUITING Phase 1 10 participants

Molecular Imaging Probes to Inform Heterogeneity in Idiopathic Pulmonary Fibrosis

University of Alabama at Birmingham

NCT04362644

RECRUITING Phase 1 8 participants

Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure

Paul Szabolcs

NCT03500731

RECRUITING Early Phase 1 6 participants

Hyperpolarized Xenon-129 MRI in Idiopathic Pulmonary Fibrosis

University of Virginia

NCT06853145

ACTIVE NOT RECRUITING Phase 3 1,255 participants

A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Idiopathic Pulmonary Fibrosis

Bristol-Myers Squibb

NCT06003426

ACTIVE NOT RECRUITING 1,000 participants

PaTH Clinical Data Research Network (CDRN) Idiopathic Pulmonary Fibrosis (IPF) Clinician Patient Partnership Cohort

University of Pittsburgh

NCT02407431

ACTIVE NOT RECRUITING 450 participants

Detection of Early Idiopathic Pulmonary Fibrosis

Temple University

NCT03457935

ACTIVE NOT RECRUITING Phase 2 240 participants

LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)

PureTech

NCT05321420

ACTIVE NOT RECRUITING NA 61 participants

Yoga Effect on Quality of Life Study Among Patients with Idiopathic Pulmonary Fibrosis

University of Washington

NCT02848625

ACTIVE NOT RECRUITING Phase 2 60 participants

Xenon MRI and Progressive ILD

Duke University

NCT05241275

ACTIVE NOT RECRUITING Phase 1 50 participants

Study of Oral Epigallocatechin-3-gallate (EGCG) in IPF Patients

Hal Chapman

NCT05195918

ACTIVE NOT RECRUITING Phase 2 34 participants

Genentech Xenon MRI Idiopathic Pulmonary Fibrosis

Duke University

NCT04071769

ACTIVE NOT RECRUITING Phase 1 24 participants

Atezolizumab for Idiopathic Pulmonary Fibrosis

Cedars-Sinai Medical Center

NCT05515627

ACTIVE NOT RECRUITING Phase 1 22 participants

Collagen-targeted Positron Emission Tomography (PET) Imaging for Assessment of EGCG Effect

Hal Chapman

NCT06265532

COMPLETED 13,264 participants

A Study Based on Medical Records That Looks at the Characteristics of Idiopathic Pulmonary Fibrosis Patients Grouped by the Type of Medication They Are Taking

Boehringer Ingelheim

NCT03958071

COMPLETED Phase 3 1,177 participants

A Study to Find Out Whether BI 1015550 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF)

Boehringer Ingelheim

NCT05321069

COMPLETED Phase 3 435 participants

Three-Arm Study of the Safety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis

Genentech

NCT00287716

COMPLETED Phase 2 325 participants

Safety and Efficacy of a Lysophosphatidic Acid Receptor Antagonist in Idiopathic Pulmonary Fibrosis

Bristol-Myers Squibb

NCT01766817

COMPLETED Phase 2 178 participants

Macitentan Use in an Idiopathic Pulmonary Fibrosis Clinical Study

Actelion

NCT00903331

COMPLETED Phase 4 89 participants

Safety and Tolerability Study of Pirfenidone in Combination With Nintedanib in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Hoffmann-La Roche

NCT02598193

COMPLETED 63 participants

Characterization of Apolipoprotein A-I Pathways in Idiopathic Pulmonary Fibrosis

National Heart, Lung, and Blood Institute (NHLBI)

NCT02315586

COMPLETED Phase 2 58 participants

GKT137831 in IPF Patients with Idiopathic Pulmonary Fibrosis

University of Alabama at Birmingham

NCT03865927

COMPLETED Phase 2 58 participants

Study of Inhaled Carbon Monoxide to Treat Idiopathic Pulmonary Fibrosis

Brigham and Women's Hospital

NCT01214187

COMPLETED Phase 1 56 participants

A Safety, Tolerability, and Pharmacokinetic Study of NIP292 in Healthy Normal Subjects

The National Institutes of Pharmaceutical R&D Co. Ltd, China

NCT04720443

COMPLETED Phase 2 52 participants

SD, IL-13 Production Rate in IPF

Novartis Pharmaceuticals

NCT00532233

COMPLETED Phase 2 44 participants

Zileuton for the Treatment of Idiopathic Pulmonary Fibrosis

University of Michigan

NCT00262405

COMPLETED NA 43 participants

Palliative Care Planner (PCplanner)

Duke University

NCT05095363

COMPLETED Early Phase 1 35 participants

Fibroblast Specific Inhibition of LOXL2 and TGFbeta1 Signaling in Patients With Pulmonary Fibrosis.

Hal Chapman

NCT03928847

COMPLETED NA 32 participants

IPF mHealth Exercise Study

University of Washington

NCT04838275

COMPLETED Phase 1 32 participants

Randomized, Crossover, Multi-Dose Pharmacokinetics of EXCL-100 Pirfenidone-Sustained Release Tablet and Esbriet in Healthy Volunteers

Excalibur Pharmaceuticals

NCT05428150

COMPLETED Phase 1 21 participants

A Study of Oral Vismodegib in Combination With Pirfenidone in Participants With Idiopathic Pulmonary Fibrosis

Hoffmann-La Roche

NCT02648048

COMPLETED 20 participants

Microaspiration in Pulmonary Fibrosis

University of California, San Francis

NCT01150591

COMPLETED Phase 2 15 participants

Safety, Tolerability, and Efficacy of MN-001 (Tipelukast) in Patients With Idiopathic Pulmonary Fibrosis

MediciNova

NCT02503657

COMPLETED Phase 2 9 participants

Phase 2a Evaluation of PLN-74809 on αvβ6 Receptor Occupancy Using PET Imaging in Participants With IPF/

Pliant Therapeutics

NCT04072315

Phase Distribution

PhaseTrial count
Early Phase 1 13
Phase 2 20
Phase 3 4
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Idiopathic Pulmonary Fibrosis Trial Landscape

ClinicalTrials.gov lists 52 US studies indexed under Idiopathic Pulmonary Fibrosis, and 22 of those are currently open to recruitment — roughly 42% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Idiopathic Pulmonary Fibrosis shows 5 late-stage studies (Phase 3 and Phase 4 combined) alongside 33 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Idiopathic Pulmonary Fibrosis is led by Boehringer Ingelheim with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 52 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Idiopathic Pulmonary Fibrosis?

PlainTrial tracks 52 US clinical trials for Idiopathic Pulmonary Fibrosis, of which 22 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Idiopathic Pulmonary Fibrosis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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