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Idiopathic Pulmonary Fibrosis
Open-data reference.
52 US clinical trials · 22 currently recruiting
Active & Recent Trials
Pulmonary Fibrosis Foundation Community Registry
Pulmonary Fibrosis Foundation
NCT05382572
A Study of the Natural Progression of Interstitial Lung Disease (ILD)
University of Chicago
NCT00470327
A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast
Boehringer Ingelheim
NCT06238622
Interstitial Lung Disease Research Unit Biobank
University of Kansas Medical Center
NCT05392881
Mechanisms of Familial Pulmonary Fibrosis
Vanderbilt University Medical Center
NCT03437486
Genomic and Proteomic Analysis of Disease Progression in Idiopathic Pulmonary Fibrosis (IPF)
University of Pittsburgh
NCT00373841
Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Idiopathic Pulmonary Fibrosis
AbbVie
NCT07230288
WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF)
Mediar Therapeutics
NCT06967805
The Role of Quantitative CT and Radiomic Biomarkers for Precision Medicine in Pulmonary Fibrosis
University of Virginia
NCT06323876
A Phase 2 Study of CAL101 in Patients With Idiopathic Pulmonary Fibrosis
Calluna Pharma AS
NCT06736990
Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Cumberland Pharmaceuticals
NCT05571059
Clinical Trial to Evaluate the Safety and Efficacy of DWN12088 in Patients With IPF
Daewoong Pharmaceutical Co.
NCT05389215
A Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GNS-3545 in Healthy Participants
Genosco
NCT07225296
A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) With or Without Standard Treatment
Boehringer Ingelheim
NCT07036523
Zinc and Nicotinamide Riboside for Idiopathic Pulmonary Fibrosis
Cedars-Sinai Medical Center
NCT06567717
H01 in Adults With Interstitial Lung Disease (The SOLIS Study)
National Institute of Environmental Health Sciences (NIEHS)
NCT06325696
A Study in People With Idiopathic Pulmonary Fibrosis to Test Whether Pirfenidone Influences the Amount of BI 1015550 in the Blood
Boehringer Ingelheim
NCT06241560
Dose-Escalation Study of Artesunate Patients With IPF
Joseph C. Wu
NCT05988463
NAL ER IPF Respiratory Function and Safety Study
Trevi Therapeutics
NCT07036029
Molecular Imaging Probes to Inform Heterogeneity in Idiopathic Pulmonary Fibrosis
University of Alabama at Birmingham
NCT04362644
Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure
Paul Szabolcs
NCT03500731
Hyperpolarized Xenon-129 MRI in Idiopathic Pulmonary Fibrosis
University of Virginia
NCT06853145
A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Idiopathic Pulmonary Fibrosis
Bristol-Myers Squibb
NCT06003426
PaTH Clinical Data Research Network (CDRN) Idiopathic Pulmonary Fibrosis (IPF) Clinician Patient Partnership Cohort
University of Pittsburgh
NCT02407431
Detection of Early Idiopathic Pulmonary Fibrosis
Temple University
NCT03457935
LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)
PureTech
NCT05321420
Yoga Effect on Quality of Life Study Among Patients with Idiopathic Pulmonary Fibrosis
University of Washington
NCT02848625
Xenon MRI and Progressive ILD
Duke University
NCT05241275
Study of Oral Epigallocatechin-3-gallate (EGCG) in IPF Patients
Hal Chapman
NCT05195918
Genentech Xenon MRI Idiopathic Pulmonary Fibrosis
Duke University
NCT04071769
Atezolizumab for Idiopathic Pulmonary Fibrosis
Cedars-Sinai Medical Center
NCT05515627
Collagen-targeted Positron Emission Tomography (PET) Imaging for Assessment of EGCG Effect
Hal Chapman
NCT06265532
A Study Based on Medical Records That Looks at the Characteristics of Idiopathic Pulmonary Fibrosis Patients Grouped by the Type of Medication They Are Taking
Boehringer Ingelheim
NCT03958071
A Study to Find Out Whether BI 1015550 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF)
Boehringer Ingelheim
NCT05321069
Three-Arm Study of the Safety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis
Genentech
NCT00287716
Safety and Efficacy of a Lysophosphatidic Acid Receptor Antagonist in Idiopathic Pulmonary Fibrosis
Bristol-Myers Squibb
NCT01766817
Macitentan Use in an Idiopathic Pulmonary Fibrosis Clinical Study
Actelion
NCT00903331
Safety and Tolerability Study of Pirfenidone in Combination With Nintedanib in Participants With Idiopathic Pulmonary Fibrosis (IPF)
Hoffmann-La Roche
NCT02598193
Characterization of Apolipoprotein A-I Pathways in Idiopathic Pulmonary Fibrosis
National Heart, Lung, and Blood Institute (NHLBI)
NCT02315586
GKT137831 in IPF Patients with Idiopathic Pulmonary Fibrosis
University of Alabama at Birmingham
NCT03865927
Study of Inhaled Carbon Monoxide to Treat Idiopathic Pulmonary Fibrosis
Brigham and Women's Hospital
NCT01214187
A Safety, Tolerability, and Pharmacokinetic Study of NIP292 in Healthy Normal Subjects
The National Institutes of Pharmaceutical R&D Co. Ltd, China
NCT04720443
SD, IL-13 Production Rate in IPF
Novartis Pharmaceuticals
NCT00532233
Zileuton for the Treatment of Idiopathic Pulmonary Fibrosis
University of Michigan
NCT00262405
Palliative Care Planner (PCplanner)
Duke University
NCT05095363
Fibroblast Specific Inhibition of LOXL2 and TGFbeta1 Signaling in Patients With Pulmonary Fibrosis.
Hal Chapman
NCT03928847
IPF mHealth Exercise Study
University of Washington
NCT04838275
Randomized, Crossover, Multi-Dose Pharmacokinetics of EXCL-100 Pirfenidone-Sustained Release Tablet and Esbriet in Healthy Volunteers
Excalibur Pharmaceuticals
NCT05428150
A Study of Oral Vismodegib in Combination With Pirfenidone in Participants With Idiopathic Pulmonary Fibrosis
Hoffmann-La Roche
NCT02648048
Microaspiration in Pulmonary Fibrosis
University of California, San Francis
NCT01150591
Safety, Tolerability, and Efficacy of MN-001 (Tipelukast) in Patients With Idiopathic Pulmonary Fibrosis
MediciNova
NCT02503657
Phase 2a Evaluation of PLN-74809 on αvβ6 Receptor Occupancy Using PET Imaging in Participants With IPF/
Pliant Therapeutics
NCT04072315
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 13 |
| Phase 2 | 20 |
| Phase 3 | 4 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Idiopathic Pulmonary Fibrosis Trial Landscape
ClinicalTrials.gov lists 52 US studies indexed under Idiopathic Pulmonary Fibrosis, and 22 of those are currently open to recruitment — roughly 42% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Idiopathic Pulmonary Fibrosis shows 5 late-stage studies (Phase 3 and Phase 4 combined) alongside 33 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Idiopathic Pulmonary Fibrosis is led by Boehringer Ingelheim with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 52 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Idiopathic Pulmonary Fibrosis?
PlainTrial tracks 52 US clinical trials for Idiopathic Pulmonary Fibrosis, of which 22 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Idiopathic Pulmonary Fibrosis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.