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NCT04262830 · ClinicalTrials.gov registry record
Cardiotoxicity Assessment Through Comprehensive Heart Imaging to Predict Heart Failure
A clinical trial of Heart Failure and Pediatric Cancer, sponsored by Hari Narayan.
- Recruiting
- Registry status
- 150
- Enrollment target
- 1
- Study location
NCT04262830: Recruiting study of Heart Failure and Pediatric Cancer, sponsored by Hari Narayan.
NCT04262830 is a study of Heart Failure and Pediatric Cancer that is actively recruiting participants, run by Hari Narayan. The registered enrollment target is 150 participants, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04262830, a study of Heart Failure and Pediatric Cancer, is actively recruiting participants, sponsored by Hari Narayan.
- RECRUITING
- Registry status
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
Anthracycline chemotherapies (e.g. doxorubicin, daunorubicin) are commonly given to treat pediatric cancer, and carry a risk of cardiotoxicity. Over the long term, children who receive these therapies have an increased risk of heart failure and early cardiovascular death. However, current strategies for identifying patients who are at risk prior to the development of significant changes in heart function are limited. This study will focus on imaging markers of cardiac injury and dysfunction with the goal of developing improved diagnostic tests and treatment strategies.
Primary Outcome
LVEF is an assessment of left ventricular global systolic function.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Cardiac magnetic resonance imaging (MRI)
- OTHER Accelerometer physical activity monitoring
Study Locations (1)
California
- Rady Children's Hospital - San Diego
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2019-09-30 |
| Est. Completion | 2030-09-30 |
What NCT04262830 shows while recruiting
NCT04262830 is an observational study that tracks outcomes without assigning an intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (93% lower).
The record links to 3 conditions, with Heart Failure appearing as the primary indexed condition, and to 2 interventions - of which Cardiac magnetic resonance imaging (MRI) is the first listed.
NCT04262830 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT04262830 about?
NCT04262830 is a clinical study titled "Cardiotoxicity Assessment Through Comprehensive Heart Imaging to Predict Heart Failure". Anthracycline chemotherapies (e.g. doxorubicin, daunorubicin) are commonly given to treat pediatric cancer, and carry a risk of cardiotoxicity. Over the long term, children who receive these therapies have an increased risk of heart failure and early cardiovascular death. However, current strategies...
What is the current status of trial NCT04262830?
This trial is currently recruiting. The enrollment target is 150 participants. The study started on 2019-09-30. Estimated completion is 2030-09-30.
What conditions does trial NCT04262830 study?
This clinical trial studies the following conditions: Heart Failure, Pediatric Cancer, Cardiotoxicity.
What interventions are being tested in trial NCT04262830?
The interventions under investigation include: Cardiac magnetic resonance imaging (MRI) (DIAGNOSTIC_TEST), Accelerometer physical activity monitoring (OTHER).
Who is sponsoring clinical trial NCT04262830?
This trial is sponsored by Hari Narayan, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04262830 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Heart Failure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04262830's enrollment target sits among peer trials
150 189th of 397 higher than 206 of 397 other Heart Failure trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Heart Failure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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Circulating Markers That Underlie the Transition From Compensated Hypertrophy to Heart Failure
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-
Integration of Telemedicine and Home-Based Cardiac Rehabilitation: Feasibility, Efficacy, and Adherence
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