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2026 data Public-data reference. official source

Hidradenitis Suppurativa

Open-data reference.

53 US clinical trials · 29 currently recruiting

Active & Recent Trials

RECRUITING 3,000 participants

Hidradenitis Suppurativa Prospective Observational Registry and Biospecimen Repository

University of California, San Francis

NCT04115566

RECRUITING Phase 3 1,328 participants

A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy

AbbVie

NCT05889182

RECRUITING Phase 3 1,280 participants

A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa

AbbVie

NCT06468228

RECRUITING 1,000 participants

Clinical and Biological Characteristics of Hidradenitis Suppurativa

University of California, San Francis

NCT03967600

RECRUITING 800 participants

Myriad™ Augmented Soft Tissue Reconstruction Registry

Aroa Biosurgery Limited

NCT05243966

RECRUITING Phase 3 555 participants

A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa

Novartis Pharmaceuticals

NCT06840392

RECRUITING Phase 3 555 participants

A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa (RECHARGE 1)

Novartis Pharmaceuticals

NCT06799000

RECRUITING Phase 3 550 participants

Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS2)

Incyte Corporation

NCT06958211

RECRUITING Phase 3 550 participants

Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS1)

Incyte Corporation

NCT06959225

RECRUITING Phase 2 240 participants

A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS.

Pfizer

NCT07228390

RECRUITING Phase 2 208 participants

Brivekimig for the Treatment of Moderate to Severe Hidradenitis Suppurativa

Sanofi

NCT07170917

RECRUITING 200 participants

Regulation of Inflammatory Genes in Hidradenitis Suppurativa

University of Alabama at Birmingham

NCT05507125

RECRUITING 175 participants

The Ohio State University Dermatology Biorepository

Ohio State University

NCT03146676

RECRUITING Phase 2 144 participants

A Study to Investigate Efficacy and Safety With SAR445399 in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Sanofi

NCT07225569

RECRUITING Phase 2 90 participants

A Study of Zasocitinib in Adults With Hidradenitis Suppurativa

Takeda

NCT07244263

RECRUITING Phase 2 60 participants

A Study to Assess Molecular Changes in Adult Participants With Moderate to Severe Hidradenitis Suppurativa or With Moderate to Severe Atopic Dermatitis Receiving Subcutaneous Injections of Lutikizumab

AbbVie

NCT06524635

RECRUITING NA 50 participants

Physical Activity in Hidradenitis Suppurativa (HS)

University of Miami

NCT06015438

RECRUITING NA 50 participants

Feasibility Study on Radiofrequency-Based Selective Electrothermolysis to Investigate Its Effects on Human Skin

Johns Hopkins University

NCT05066113

RECRUITING Phase 3 40 participants

A Study to Assess the Pharmacokinetics and Safety of Bimekizumab in Children and Adolescents With Moderate to Severe Hidradenitis Suppurativa

UCB Biopharma SRL

NCT06921850

RECRUITING Phase 3 35 participants

An Open-label, Single-arm Study to Evaluate Pharmacokinetics and Safety of Subcutaneous Sonelokimab in Adolescents With Moderate to Severe Hidradenitis Suppurativa (VELA-TEEN)

MoonLake Immunotherapeutics

NCT06768671

RECRUITING NA 32 participants

Battlefield Acupuncture for Pain in Hidradenitis Suppurativa

Wayne State University

NCT04218422

RECRUITING Phase 2 24 participants

Topical Ruxolitinib 1.5% for Hidradenitis Suppurativa Treatment

Milton S. Hershey Medical Center

NCT04414514

RECRUITING Phase 1 24 participants

Study to Evaluate the Maximal Use of Ruxolitinib Cream in Adult and Adolescent Participants With Hidradenitis Suppurativa

Incyte Corporation

NCT07049575

RECRUITING Phase 1 20 participants

A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)

UCB Biopharma SRL

NCT06888193

RECRUITING 20 participants

Botulinum Toxin Therapy in Hidradenitis Suppurativa

University of Massachusetts, Worcester

NCT05403710

RECRUITING Early Phase 1 16 participants

Capsule Microbiota Transplant Therapy for Hidradenitis Suppurativa

University of Minnesota

NCT06058520

RECRUITING Early Phase 1 12 participants

An Open-label, Time-lagged, Dose-escalation Study to Evalaute the Safety and Efficacy of Subcutaneous Siplizumab in the Treatment of Hidradenitis Suppurativa.

University of Alabama at Birmingham

NCT06326476

RECRUITING Phase 2 10 participants

A Study for Evaluating Safety & Efficacy of Topical Roflumilast 0.3% Foam in Hidradenitis Suppurativa

Tulane University

NCT07077902

RECRUITING NA 8 participants

Aviclear for Hidradenitis Suppurativa (HS)

University of Miami

NCT06801795

ACTIVE NOT RECRUITING 15,000 participants

A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC

Target PharmaSolutions

NCT03661866

ACTIVE NOT RECRUITING Phase 3 703 participants

Extension Study to Assess Effects of Non-interrupted Versus Interrupted and Long Term Treatment of Two Dose Regimes of Secukinumab in Subjects With Hidradenitis Suppurativa

Novartis Pharmaceuticals

NCT04179175

ACTIVE NOT RECRUITING Phase 3 658 participants

A Study to Test the Long-term Treatment of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa

UCB Biopharma SRL

NCT04901195

ACTIVE NOT RECRUITING Phase 3 422 participants

A Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

MoonLake Immunotherapeutics

NCT06411899

ACTIVE NOT RECRUITING Phase 3 418 participants

Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

MoonLake Immunotherapeutics

NCT06411379

ACTIVE NOT RECRUITING Phase 2 352 participants

A Study of Eltrekibart (LY3041658) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Eli Lilly and Company

NCT06046729

ACTIVE NOT RECRUITING Phase 2 250 participants

A Study to Evaluate the Efficacy and Safety of AVTX-009 in Patients With Moderate to Severe Hidradenitis Suppurativa

Avalo Therapeutics

NCT06603077

ACTIVE NOT RECRUITING Phase 2 248 participants

Study of Efficacy and Safety of Investigational Treatments in Patients With Moderate to Severe Hidradenitis Suppurativa

Novartis Pharmaceuticals

NCT03827798

ACTIVE NOT RECRUITING Phase 2 214 participants

A Study of the Efficacy and Safety of Brensocatib in Adults With Moderate to Severe Hidradenitis Suppurativa (HS)

Insmed Incorporated

NCT06685835

ACTIVE NOT RECRUITING Phase 2 210 participants

A Study to Assess Disease Activity and Safety of Subcutaneous Lutikizumab (ABT-981) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-Tumor Necrosis Factor (TNF) Therapy and Who Are Naïve to Biologic Therapy

AbbVie

NCT05139602

ACTIVE NOT RECRUITING Phase 2 147 participants

Study to Evaluate Tulisokibart for Hidradenitis Suppurativa (MK-7240-012)

Merck Sharp & Dohme

NCT06956235

ACTIVE NOT RECRUITING Phase 1 24 participants

Study of Single Doses of SBT777101 in Subjects With Hidradenitis Suppurativa

Sonoma Biotherapeutics

NCT06361836

ACTIVE NOT RECRUITING Phase 2 15 participants

Anifrolumab for Hidradenitis Suppurativa

University of North Carolina, Chapel Hill

NCT06374212

COMPLETED Phase 3 545 participants

Study of Efficacy and Safety of Two Secukinumab Dose Regimens in Subjects With Moderate to Severe Hidradenitis Suppurativa (HS)

Novartis Pharmaceuticals

NCT03713632

COMPLETED Phase 3 505 participants

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa

UCB Biopharma SRL

NCT04242446

COMPLETED Phase 2 86 participants

A Study to Test the Efficacy and Safety of SAR442970 in Adults With Hidradenitis Suppurativa

Sanofi

NCT05849922

COMPLETED Phase 2 72 participants

A Study of LY3041658 in Adults With Hidradenitis Suppurativa

Eli Lilly and Company

NCT04493502

COMPLETED 67 participants

Hidradenitis Suppurativa Mail Survey

Wake Forest University Health Sciences

NCT03572738

COMPLETED NA 20 participants

Study on the Effect of NdYag Laser for the Treatment of Hidradenitis Suppurativa

Henry Ford Health System

NCT00494351

COMPLETED Phase 2 20 participants

Single Center Study of Apremilast for the Treatment of Hidradenitis Suppurativa

Florida Academic Dermatology Centers

NCT02695212

COMPLETED NA 18 participants

Trial Comparing Efficacy of Treatments for Hidradenitis Suppurativa

Henry Ford Health System

NCT01063270

COMPLETED NA 15 participants

Hidradenitis Suppurativa (HS) Tunneling Wounds

University of Miami

NCT04648631

COMPLETED Phase 2 10 participants

A Study of the Safety of INCB054707 in Participants With Hidradenitis Suppurativa

Incyte Corporation

NCT03569371

COMPLETED Phase 2 6 participants

Anakinra as a Treatment for Hydradenitis Suppurativa

University of California, San Francis

NCT01516749

Phase Distribution

PhaseTrial count
Early Phase 1 5
Phase 2 19
Phase 3 14

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Hidradenitis Suppurativa Trial Landscape

ClinicalTrials.gov lists 53 US studies indexed under Hidradenitis Suppurativa, and 29 of those are currently open to recruitment — roughly 55% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Hidradenitis Suppurativa shows 14 late-stage studies (Phase 3 and Phase 4 combined) alongside 24 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Hidradenitis Suppurativa is led by Novartis Pharmaceuticals with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 53 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Hidradenitis Suppurativa?

PlainTrial tracks 53 US clinical trials for Hidradenitis Suppurativa, of which 29 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Hidradenitis Suppurativa?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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