Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 29 recruiting now early-phase tilt

Hidradenitis Suppurativa: early-phase trial registry

29 of 53 indexed Hidradenitis Suppurativa trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #265 of 28,707 conditions by registered trial count.

53 US clinical trials · 29 currently recruiting · #265 of 28,707 conditions by registered trial count

Hidradenitis Suppurativa: 53 US clinical trials tracked, 29 recruiting.

Hidradenitis Suppurativa is the subject of 53 registered US clinical trials on ClinicalTrials.gov, 29 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 24 in Phase 1-2 (earlier-stage). The most active sponsor is Novartis Pharmaceuticals, running 5 of these trials.

Enrollment posture brief

Registry condition hidradenitis-suppurativa

OPEN 29 | RECR 55% | LATE 14 | EARLY 24 | RANK #265 | SPON 5

Nearest open-share peer: Anatomic Stage I Breast Cancer AJCC v8 (55% recruiting · 64 trials)

Mental Health Issue73.6%Metastatic Solid Tumor69.8%Hidradenitis Suppurativa (th…55%Depressive Disorder, Major26.4%Medication Adherence24.5%
Open-enrollment share among volume-matched conditions near Hidradenitis Suppurativa

Hidradenitis Suppurativa lists 29 open slots (55% of 53 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Hidradenitis Suppurativa on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Hidradenitis Suppurativa is recruiting above its size-band peers.

    29 of 53 indexed trials (54.7%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Hidradenitis Suppurativa trials is spread across many organizations.

    Novartis Pharmaceuticals accounts for 5 of 53 trials (9.4%). 29 distinct sponsors appear on at least one study for this condition label.

  3. Typical Hidradenitis Suppurativa enrolment sits around 144 participants.

    Median target enrolment is 144 among the 53 trials that report a genuine target (sentinel values excluded). 26 of those (49.1%) plan for fewer than 100 participants.

  4. Hidradenitis Suppurativa research is mostly interventional.

    45 interventional and 8 observational studies make up this index (84.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 15Phase 219Phase 314

Open and recent trials

53 total, page 1 of 2

RECRUITING 3,000 participants

Hidradenitis Suppurativa Prospective Observational Registry and Biospecimen Repository

University of California, San Francisco

NCT04115566

RECRUITING Phase 3 1,328 participants

A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy

AbbVie

NCT05889182

RECRUITING Phase 3 1,280 participants

A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa

AbbVie

NCT06468228

RECRUITING 1,000 participants

Clinical and Biological Characteristics of Hidradenitis Suppurativa

University of California, San Francisco

NCT03967600

RECRUITING 800 participants

Myriad™ Augmented Soft Tissue Reconstruction Registry

Aroa Biosurgery Limited

NCT05243966

RECRUITING Phase 3 555 participants

A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa

Novartis Pharmaceuticals

NCT06840392

RECRUITING Phase 3 555 participants

A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa (RECHARGE 1)

Novartis Pharmaceuticals

NCT06799000

RECRUITING Phase 3 550 participants

Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS2)

Incyte Corporation

NCT06958211

RECRUITING Phase 3 550 participants

Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS1)

Incyte Corporation

NCT06959225

RECRUITING Phase 2 240 participants

A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS.

Pfizer

NCT07228390

RECRUITING Phase 2 208 participants

Brivekimig for the Treatment of Moderate to Severe Hidradenitis Suppurativa

Sanofi

NCT07170917

RECRUITING 200 participants

Regulation of Inflammatory Genes in Hidradenitis Suppurativa

University of Alabama at Birmingham

NCT05507125

RECRUITING 175 participants

The Ohio State University Dermatology Biorepository

Ohio State University

NCT03146676

RECRUITING Phase 2 144 participants

A Study to Investigate Efficacy and Safety With SAR445399 in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Sanofi

NCT07225569

RECRUITING Phase 2 90 participants

A Study of Zasocitinib in Adults With Hidradenitis Suppurativa

Takeda

NCT07244263

RECRUITING Phase 2 60 participants

A Study to Assess Molecular Changes in Adult Participants With Moderate to Severe Hidradenitis Suppurativa or With Moderate to Severe Atopic Dermatitis Receiving Subcutaneous Injections of Lutikizumab

AbbVie

NCT06524635

RECRUITING NA 50 participants

Physical Activity in Hidradenitis Suppurativa (HS)

University of Miami

NCT06015438

RECRUITING NA 50 participants

Feasibility Study on Radiofrequency-Based Selective Electrothermolysis to Investigate Its Effects on Human Skin

Johns Hopkins University

NCT05066113

RECRUITING Phase 3 40 participants

A Study to Assess the Pharmacokinetics and Safety of Bimekizumab in Children and Adolescents With Moderate to Severe Hidradenitis Suppurativa

UCB Biopharma SRL

NCT06921850

RECRUITING Phase 3 35 participants

An Open-label, Single-arm Study to Evaluate Pharmacokinetics and Safety of Subcutaneous Sonelokimab in Adolescents With Moderate to Severe Hidradenitis Suppurativa (VELA-TEEN)

MoonLake Immunotherapeutics

NCT06768671

RECRUITING NA 32 participants

Battlefield Acupuncture for Pain in Hidradenitis Suppurativa

Wayne State University

NCT04218422

RECRUITING Phase 2 24 participants

Topical Ruxolitinib 1.5% for Hidradenitis Suppurativa Treatment

Milton S. Hershey Medical Center

NCT04414514

RECRUITING Phase 1 24 participants

Study to Evaluate the Maximal Use of Ruxolitinib Cream in Adult and Adolescent Participants With Hidradenitis Suppurativa

Incyte Corporation

NCT07049575

RECRUITING Phase 1 20 participants

A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)

UCB Biopharma SRL

NCT06888193

RECRUITING 20 participants

Botulinum Toxin Therapy in Hidradenitis Suppurativa

University of Massachusetts, Worcester

NCT05403710

RECRUITING Early Phase 1 16 participants

Capsule Microbiota Transplant Therapy for Hidradenitis Suppurativa

University of Minnesota

NCT06058520

RECRUITING Early Phase 1 12 participants

An Open-label, Time-lagged, Dose-escalation Study to Evalaute the Safety and Efficacy of Subcutaneous Siplizumab in the Treatment of Hidradenitis Suppurativa.

University of Alabama at Birmingham

NCT06326476

RECRUITING Phase 2 10 participants

A Study for Evaluating Safety & Efficacy of Topical Roflumilast 0.3% Foam in Hidradenitis Suppurativa

Tulane University

NCT07077902

RECRUITING NA 8 participants

Aviclear for Hidradenitis Suppurativa (HS)

University of Miami

NCT06801795

ACTIVE NOT RECRUITING 15,000 participants

A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC

Target PharmaSolutions

NCT03661866

ACTIVE NOT RECRUITING Phase 3 703 participants

Extension Study to Assess Effects of Non-interrupted Versus Interrupted and Long Term Treatment of Two Dose Regimes of Secukinumab in Subjects With Hidradenitis Suppurativa

Novartis Pharmaceuticals

NCT04179175

ACTIVE NOT RECRUITING Phase 3 658 participants

A Study to Test the Long-term Treatment of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa

UCB Biopharma SRL

NCT04901195

ACTIVE NOT RECRUITING Phase 3 422 participants

A Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

MoonLake Immunotherapeutics

NCT06411899

ACTIVE NOT RECRUITING Phase 3 418 participants

Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

MoonLake Immunotherapeutics

NCT06411379

ACTIVE NOT RECRUITING Phase 2 352 participants

A Study of Eltrekibart (LY3041658) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Eli Lilly and Company

NCT06046729

ACTIVE NOT RECRUITING Phase 2 250 participants

A Study to Evaluate the Efficacy and Safety of AVTX-009 in Patients With Moderate to Severe Hidradenitis Suppurativa

Avalo Therapeutics

NCT06603077

ACTIVE NOT RECRUITING Phase 2 248 participants

Study of Efficacy and Safety of Investigational Treatments in Patients With Moderate to Severe Hidradenitis Suppurativa

Novartis Pharmaceuticals

NCT03827798

ACTIVE NOT RECRUITING Phase 2 214 participants

A Study of the Efficacy and Safety of Brensocatib in Adults With Moderate to Severe Hidradenitis Suppurativa (HS)

Insmed Incorporated

NCT06685835

ACTIVE NOT RECRUITING Phase 2 210 participants

A Study to Assess Disease Activity and Safety of Subcutaneous Lutikizumab (ABT-981) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-Tumor Necrosis Factor (TNF) Therapy and Who Are Naïve to Biologic Therapy

AbbVie

NCT05139602

ACTIVE NOT RECRUITING Phase 2 147 participants

Study to Evaluate Tulisokibart for Hidradenitis Suppurativa (MK-7240-012)

Merck Sharp & Dohme

NCT06956235

ACTIVE NOT RECRUITING Phase 1 24 participants

Study of Single Doses of SBT777101 in Subjects With Hidradenitis Suppurativa

Sonoma Biotherapeutics

NCT06361836

ACTIVE NOT RECRUITING Phase 2 15 participants

Anifrolumab for Hidradenitis Suppurativa

University of North Carolina, Chapel Hill

NCT06374212

COMPLETED Phase 3 545 participants

Study of Efficacy and Safety of Two Secukinumab Dose Regimens in Subjects With Moderate to Severe Hidradenitis Suppurativa (HS)

Novartis Pharmaceuticals

NCT03713632

COMPLETED Phase 3 505 participants

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa

UCB Biopharma SRL

NCT04242446

COMPLETED Phase 2 86 participants

A Study to Test the Efficacy and Safety of SAR442970 in Adults With Hidradenitis Suppurativa

Sanofi

NCT05849922

COMPLETED Phase 2 72 participants

A Study of LY3041658 in Adults With Hidradenitis Suppurativa

Eli Lilly and Company

NCT04493502

COMPLETED 67 participants

Hidradenitis Suppurativa Mail Survey

Wake Forest University Health Sciences

NCT03572738

COMPLETED NA 20 participants

Study on the Effect of NdYag Laser for the Treatment of Hidradenitis Suppurativa

Henry Ford Health System

NCT00494351

COMPLETED Phase 2 20 participants

Single Center Study of Apremilast for the Treatment of Hidradenitis Suppurativa

Florida Academic Dermatology Centers

NCT02695212

COMPLETED NA 18 participants

Trial Comparing Efficacy of Treatments for Hidradenitis Suppurativa

Henry Ford Health System

NCT01063270

Page 1 of 2 Next →

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 19
Phase 3 14

Named interventions

Most-linked intervention names on Hidradenitis Suppurativa records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
15 trials
Bimekizumab Drug
4 trials
Sonelokimab Drug
3 trials
Ruxolitinib Cream Drug
3 trials
Vehicle Cream Drug
2 trials
Lutikizumab Drug
2 trials
Placebo 2 Drug
2 trials
Placebo 1 Drug
2 trials

US sites by state

Facility locations filed on Hidradenitis Suppurativa trials. A trial with sites in several states counts in each.

Florida 34 trials
California 33 trials
Georgia 19 trials
Arizona 19 trials
Michigan 17 trials
Indiana 17 trials
Massachusetts 15 trials
Arkansas 13 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Hidradenitis Suppurativa page

53 registered trials, 29 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Hidradenitis Suppurativa condition card totals 53 registered trials; most-linked intervention Placebo; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.