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Congestive Heart Failure: early-phase trial registry
8 of 52 indexed Congestive Heart Failure trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #271 of 28,707 conditions by registered trial count.
52 US clinical trials · 8 currently recruiting · #271 of 28,707 conditions by registered trial count
Congestive Heart Failure: 52 US clinical trials tracked, 8 recruiting.
Congestive Heart Failure is the subject of 52 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Abbott Medical Devices, running 3 of these trials.
Enrollment posture brief
Registry condition congestive-heart-failure
OPEN 8 | RECR 15% | LATE 3 | EARLY 9 | RANK #271 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Arthroplasty, Replacement, Knee (15% recruiting · 13 trials)
Congestive Heart Failure lists 8 open slots (15% of 52 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Congestive Heart Failure on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Congestive Heart Failure is recruiting below its size-band peers.
8 of 52 indexed trials (15.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Congestive Heart Failure trials is spread across many organizations.
Abbott Medical Devices accounts for 3 of 52 trials (5.8%). 40 distinct sponsors appear on at least one study for this condition label.
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Typical Congestive Heart Failure enrolment sits around 139 participants.
Median target enrolment is 139 among the 52 trials that report a genuine target (sentinel values excluded). 23 of those (44.2%) plan for fewer than 100 participants.
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Congestive Heart Failure research is mostly interventional.
41 interventional and 11 observational studies make up this index (78.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
52 total, page 1 of 2
Care Transitions App for Patients With Multiple Chronic Conditions
Brigham and Women's Hospital
NCT06051058
Circulating Markers for Ischemic Heart Disease
UConn Health
NCT00762333
Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence
University of Tennessee
NCT06374277
Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease
University of Utah
NCT01099982
TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer
Mayo Clinic
NCT05507879
Stress and Congestive Heart Failure
Yale University
NCT04551560
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction
Sardocor
NCT04703842
Palliative Care for People With HF
Indiana University
NCT07356843
SyncAV Post-Market Trial
Abbott Medical Devices
NCT04100148
Quasi-Randomized Evaluation of the UCLA Next Day Clinic (NDC)
University of California, Los Angeles
NCT06526884
Plasma ExtrAcellular RNAs and Biomarkers of Heart FaiLure During Decongestion: PEARL-HF Study
Massachusetts General Hospital
NCT02632656
Prediction of ARrhythmic Events With Positron Emission Tomography II
State University of New York at Buffalo
NCT03493516
Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects With Non-Ischemic NYHA Class III Heart Failure
AskBio
NCT05598333
AB-1002 in Patients With Class III Heart Failure
AskBio
NCT04179643
Improving Patient Prioritization During Hospital-homecare Transition
Columbia University
NCT04136951
MADIT-CRT: Multicenter Automatic Defibrillator Implantation With Cardiac Resynchronization Therapy
Boston Scientific Corporation
NCT00180271
Tele-HF: Yale Heart Failure Telemonitoring Study
Yale University
NCT00303212
CardioMEMS HF System Post Approval Study
Abbott Medical Devices
NCT02279888
PROSPECT: Predictors of Response to Cardiac Re-Synchronization Therapy
Medtronic Cardiac Rhythm and Heart Failure
NCT00253357
Device Evaluation of Contak Renewal 2and Easytrak 2 - DECREASE-HF
Boston Scientific Corporation
NCT00158951
Aetna_Intel Medicare Home Biomonitoring Study
Aetna
NCT01105572
At-Home Automated External Defibrillator (AED) Training Study
Public Health - Seattle and King County
NCT00219674
Empowering Elders Through Technology
Robert Wood Johnson Foundation
NCT00261664
Evaluating a Low-Literacy Discharge Medication Education Tool
University of California, Los Angeles
NCT00408733
Social Risk Score, Clinical Decision Support Tool and Closed Loop Referral for Social Risk Screen and Referral
Johns Hopkins University
NCT05574699
Safety and Efficacy Study of Once and Twice Daily Doses of MCC-135 in Subjects With Congestive Heart Failure.
Takeda
NCT00050076
Does Detailed Informed Consent for Cardiopulmonary Resuscitation and Mechanical Ventilation Impact Patients' Decisions and Outcomes?
Jewish Hospital, Cincinnati, Ohio
NCT01878968
Insomnia Self-Management in Heart Failure
Yale University
NCT02660385
DILIPO (DILutIonal HyPOnatremia)
Sanofi
NCT00274326
Stepped Care vs Center-based Cardiopulmonary Rehabilitation for Older Frail Adults Living in Rural MA
Peter Lindenauer, MD
NCT05562037
Health Literacy in Patients With Congestive Heart Failure
Griffin Hospital
NCT00508716
Leveraging Home Health Aides to Improve Outcomes in Heart Failure
Weill Medical College of Cornell University
NCT04239911
Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions
Treatment Research Institute
NCT02059005
Study to Evaluate the Safety of Twice Daily Oral Carvedilol
Shaddy, Robert, M.D.
NCT00129363
Congestive Heart Failure Weight Study
Central DuPage Hospital
NCT01185249
Mind-body Interventions in Cardiac Patients
Massachusetts General Hospital
NCT01270568
Utility of Serial BNP Levels in Emergency Department CHF
Ohio State University
NCT00534066
Rosiglitazone to Treat Patients With Heart Failure and Glucose Intolerance or Type II Diabetes
National Heart, Lung, and Blood Institute (NHLBI)
NCT00064727
Evaluation of the EasySense System in Congestive Heart Failure
Ohio State University
NCT03237923
Heart Failure Patient Self-Management Web Portal Pilot Study
University of Michigan
NCT01009151
Advanced Wireless, Wearable Sensors for Continuous Hemodynamic Monitoring
Northwestern University
NCT04362553
His Bundle Pacing Versus Coronary Sinus Pacing for Cardiac Resynchronization Therapy
University of Chicago
NCT02700425
Cardiac Stem Cell Infusion in Patients With Ischemic CardiOmyopathy (SCIPIO)
University of Louisville
NCT00474461
Daxor - Blood Volume Analysis
Duke University
NCT04111185
Inhaled Beta-adrenergic Agonists to Treat Pulmonary Vascular Disease in Heart Failure With Preserved EF (BEAT HFpEF): A Randomized Controlled Trial
Mayo Clinic
NCT02885636
Study of Coronary Artery Disease by Two Types of Angiography
VA Connecticut Healthcare System
NCT00273819
Researching Emotions And Cardiac Health
Massachusetts General Hospital
NCT02737761
Hemodynamic Effects of Spironolactone in Patients With Heart Failure
University of Toledo Health Science Campus
NCT00860340
EnSite NavX-Guided Coronary Sinus Mapping During CRT Implant
Abbott Medical Devices
NCT01615835
Congestive Heart Failure Pilot Study Utilizing Wireless Home Scale and Daily Symptom Monitoring
University of Pennsylvania
NCT03234088
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 5 |
| Phase 3 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Congestive Heart Failure records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Congestive Heart Failure trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Congestive Heart Failure page
52 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 8 Congestive Heart Failure trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Abbott Medical Devices sponsors the most Congestive Heart Failure trials on record, review their full trial history before evaluating a specific study. See Abbott Medical Devices's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Congestive Heart Failure condition card totals 52 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.