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Congestive Heart Failure
Open-data reference.
52 US clinical trials · 8 currently recruiting
Active & Recent Trials
Care Transitions App for Patients With Multiple Chronic Conditions
Brigham and Women's Hospital
NCT06051058
Circulating Markers for Ischemic Heart Disease
UConn Health
NCT00762333
Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence
University of Tennessee
NCT06374277
Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease
University of Utah
NCT01099982
TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer
Mayo Clinic
NCT05507879
Stress and Congestive Heart Failure
Yale University
NCT04551560
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction
Sardocor
NCT04703842
Palliative Care for People With HF
Indiana University
NCT07356843
SyncAV Post-Market Trial
Abbott Medical Devices
NCT04100148
Quasi-Randomized Evaluation of the UCLA Next Day Clinic (NDC)
University of California, Los Angeles
NCT06526884
Plasma ExtrAcellular RNAs and Biomarkers of Heart FaiLure During Decongestion: PEARL-HF Study
Massachusetts General Hospital
NCT02632656
Prediction of ARrhythmic Events With Positron Emission Tomography II
State University of New York at Buffalo
NCT03493516
Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects With Non-Ischemic NYHA Class III Heart Failure
AskBio
NCT05598333
AB-1002 in Patients With Class III Heart Failure
AskBio
NCT04179643
Improving Patient Prioritization During Hospital-homecare Transition
Columbia University
NCT04136951
MADIT-CRT: Multicenter Automatic Defibrillator Implantation With Cardiac Resynchronization Therapy
Boston Scientific Corporation
NCT00180271
Tele-HF: Yale Heart Failure Telemonitoring Study
Yale University
NCT00303212
CardioMEMS HF System Post Approval Study
Abbott Medical Devices
NCT02279888
PROSPECT: Predictors of Response to Cardiac Re-Synchronization Therapy
Medtronic Cardiac Rhythm and Heart Failure
NCT00253357
Device Evaluation of Contak Renewal 2and Easytrak 2 - DECREASE-HF
Boston Scientific Corporation
NCT00158951
Aetna_Intel Medicare Home Biomonitoring Study
Aetna
NCT01105572
At-Home Automated External Defibrillator (AED) Training Study
Public Health - Seattle and King County
NCT00219674
Empowering Elders Through Technology
Robert Wood Johnson Foundation
NCT00261664
Evaluating a Low-Literacy Discharge Medication Education Tool
University of California, Los Angeles
NCT00408733
Social Risk Score, Clinical Decision Support Tool and Closed Loop Referral for Social Risk Screen and Referral
Johns Hopkins University
NCT05574699
Safety and Efficacy Study of Once and Twice Daily Doses of MCC-135 in Subjects With Congestive Heart Failure.
Takeda
NCT00050076
Does Detailed Informed Consent for Cardiopulmonary Resuscitation and Mechanical Ventilation Impact Patients' Decisions and Outcomes?
Jewish Hospital, Cincinnati, Ohio
NCT01878968
Insomnia Self-Management in Heart Failure
Yale University
NCT02660385
DILIPO (DILutIonal HyPOnatremia)
Sanofi
NCT00274326
Stepped Care vs Center-based Cardiopulmonary Rehabilitation for Older Frail Adults Living in Rural MA
Peter Lindenauer, MD
NCT05562037
Health Literacy in Patients With Congestive Heart Failure
Griffin Hospital
NCT00508716
Leveraging Home Health Aides to Improve Outcomes in Heart Failure
Weill Medical College of Cornell University
NCT04239911
Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions
Treatment Research Institute
NCT02059005
Study to Evaluate the Safety of Twice Daily Oral Carvedilol
Shaddy, Robert, M.D.
NCT00129363
Congestive Heart Failure Weight Study
Central DuPage Hospital
NCT01185249
Mind-body Interventions in Cardiac Patients
Massachusetts General Hospital
NCT01270568
Utility of Serial BNP Levels in Emergency Department CHF
Ohio State University
NCT00534066
Rosiglitazone to Treat Patients With Heart Failure and Glucose Intolerance or Type II Diabetes
National Heart, Lung, and Blood Institute (NHLBI)
NCT00064727
Evaluation of the EasySense System in Congestive Heart Failure
Ohio State University
NCT03237923
Heart Failure Patient Self-Management Web Portal Pilot Study
University of Michigan
NCT01009151
Advanced Wireless, Wearable Sensors for Continuous Hemodynamic Monitoring
Northwestern University
NCT04362553
His Bundle Pacing Versus Coronary Sinus Pacing for Cardiac Resynchronization Therapy
University of Chicago
NCT02700425
Cardiac Stem Cell Infusion in Patients With Ischemic CardiOmyopathy (SCIPIO)
University of Louisville
NCT00474461
Daxor - Blood Volume Analysis
Duke University
NCT04111185
Inhaled Beta-adrenergic Agonists to Treat Pulmonary Vascular Disease in Heart Failure With Preserved EF (BEAT HFpEF): A Randomized Controlled Trial
Mayo Clinic
NCT02885636
Study of Coronary Artery Disease by Two Types of Angiography
VA Connecticut Healthcare System
NCT00273819
Researching Emotions And Cardiac Health
Massachusetts General Hospital
NCT02737761
Hemodynamic Effects of Spironolactone in Patients With Heart Failure
University of Toledo Health Science Campus
NCT00860340
EnSite NavX-Guided Coronary Sinus Mapping During CRT Implant
Abbott Medical Devices
NCT01615835
Congestive Heart Failure Pilot Study Utilizing Wireless Home Scale and Daily Symptom Monitoring
University of Pennsylvania
NCT03234088
A Comparison of Hydrochlorothiazide and Metolazone in Combination With Furosemide in Congestive Heart Failure Patients
University of New Mexi
NCT00690521
Effective Management of Emotional Response to Generate Well-Being Post-HF Exacerbation
Duke University
NCT03043261
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 4 |
| Phase 2 | 5 |
| Phase 3 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Congestive Heart Failure Trial Landscape
ClinicalTrials.gov lists 52 US studies indexed under Congestive Heart Failure, and 8 of those are currently open to recruitment — roughly 15% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Congestive Heart Failure shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 9 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Congestive Heart Failure is led by Abbott Medical Devices with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 52 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Congestive Heart Failure?
PlainTrial tracks 52 US clinical trials for Congestive Heart Failure, of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Congestive Heart Failure?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.