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NCT05120518 · ClinicalTrials.gov registry record

Post Mortem Tissue Donation of Pediatric Tumor Tissues and Cells

A clinical trial of Pediatric Cancer, sponsored by Ann & Robert H Lurie Children's Hospital of Chicago.

Recruiting
Registry status
150
Enrollment target
1
Study location

NCT05120518: Recruiting study of Pediatric Cancer, sponsored by Ann & Robert H Lurie Children's Hospital of Chicago.

NCT05120518 is a study of Pediatric Cancer that is actively recruiting participants, run by Ann & Robert H Lurie Children's Hospital of Chicago. The registered enrollment target is 150 participants, below the 1,488-participant average among 51 other Pediatric Cancer trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05120518, a study of Pediatric Cancer, is actively recruiting participants, sponsored by Ann & Robert H Lurie Children's Hospital of Chicago.

RECRUITING
Registry status
150 participants
Enrollment target
1
Study location

Study Summary

The objective of this study is to utilize all donated pediatric tumor tissues and cells obtained from autopsy to prospectively develop novel patient derived orthotopic xenograft (PDOX) mouse models as well as in vitro cell culture model systems for pediatric cancers, and also provide tissue samples to other researchers and organizations (eg, CBTN, DIPG Registry, COG).

Primary Outcome

Procurement of pediatric cancer and non-cancer tumor tissue during autopsy with signed consent. Tissue will be collected through a research tissue collection autopsy of the original tumor and other sites that are appropriate. Samples of both tumor and normal cells will be collected in addition to body fluids such as cerebrospinal fluid (CSF), blood, bone marrow, and skin biopsies for genomic testing.

Conditions Studied

Interventions

  • OTHER Collection of post mortem tissue donation

Study Locations (1)

Illinois

  • Ann & Robert H. Lurie Children's Hospital of Chicago - Chicago

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2019-08-14
Est. Completion 2029-08-14

What NCT05120518 shows while recruiting

NCT05120518 is an observational study that tracks outcomes without assigning an intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 1,488-participant average among 51 other Pediatric Cancer trials with a reported enrollment target (90% lower).

The record links to 1 condition, with Pediatric Cancer appearing as the primary indexed condition, and to 1 intervention - of which Collection of post mortem tissue donation is the first listed.

NCT05120518 reports a single indexed study location in Illinois.

Frequently Asked Questions

What is clinical trial NCT05120518 about?

NCT05120518 is a clinical study titled "Post Mortem Tissue Donation of Pediatric Tumor Tissues and Cells". The objective of this study is to utilize all donated pediatric tumor tissues and cells obtained from autopsy to prospectively develop novel patient derived orthotopic xenograft (PDOX) mouse models as well as in vitro cell culture model systems for pediatric cancers, and also provide tissue samples ...

What is the current status of trial NCT05120518?

This trial is currently recruiting. The enrollment target is 150 participants. The study started on 2019-08-14. Estimated completion is 2029-08-14.

What conditions does trial NCT05120518 study?

This clinical trial studies the following conditions: Pediatric Cancer.

What interventions are being tested in trial NCT05120518?

The interventions under investigation include: Collection of post mortem tissue donation (OTHER).

Who is sponsoring clinical trial NCT05120518?

This trial is sponsored by Ann & Robert H Lurie Children's Hospital of Chicago, which has 159 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05120518 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Pediatric Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05120518's enrollment target sits among peer trials

150 17th of 51 higher than 33 of 51 other Pediatric Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Pediatric Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05120518, the US trial registry maintained by the National Library of Medicine. NCT05120518 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.