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NCT03739372 · ClinicalTrials.gov registry record · NA
Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma
A NA study of Cancer and Glioblastoma, sponsored by University of California, San Francisco.
- Active
- Registry status
- NA
- Development phase
- 44
- Enrollment target
- 12
- Study locations
NCT03739372: Active NA study of Cancer and Glioblastoma, sponsored by University of California, San Francisco.
NCT03739372 is a NA study of Cancer and Glioblastoma that is active but no longer recruiting, run by University of California, San Francisco. The registered enrollment target is 44 participants, below the 3,491-participant average among 615 other Cancer trials with a reported enrollment target (99% lower). The trial reports 12 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03739372, a NA study of Cancer and Glioblastoma, is active but no longer recruiting, sponsored by University of California, San Francisco.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 44 participants
- Enrollment target
- 12
- Study locations
Study Summary
This is a 2 strata pilot trial within the Pacific Pediatric Neuro-Oncology Consortium (PNOC). The study will use a new treatment approach based on each patient's tumor gene expression, whole-exome sequencing (WES), targeted panel profile (UCSF 500 gene panel), and RNA-Seq. The current study will test the efficacy of such an approach in children with High-grade gliomas HGG.
Primary Outcome
Progression Free Survival will be determined from date of confirmation of response to first evidence of progression or death at the 12 month time point.
Conditions Studied
Interventions
- OTHER Specialized tumor board recommendation
Study Locations (12)
California
- University of California, San Diego Rady Children's Hospital - San Diego
- University of California, San Francisco - San Francisco
District of Columbia
- Children's National Medical Center - Washington D.C.
Florida
- University of Florida - Gainesville
Illinois
- Ann & Robert H. Lurie Children's Hospital of Chicago - Chicago
Maryland
- Johns Hopkins University - Baltimore
Minnesota
- Children's Hospitals and Clinics of Minneapolis - Minneapolis
Missouri
- Washington University - St Louis
Ohio
- Nationwide Children's Hospital - Columbus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2018-11-28 |
| Est. Completion | 2027-01-01 |
| Phase | NA |
What the registry record for NCT03739372 still lists
NCT03739372 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 3,491-participant average among 615 other Cancer trials with a reported enrollment target (99% lower).
The record links to 8 conditions, with Cancer appearing as the primary indexed condition, and to 1 intervention - of which Specialized tumor board recommendation is the first listed.
NCT03739372 lists 12 locations in 11 states (California, District of Columbia, Florida).
Frequently Asked Questions
What is clinical trial NCT03739372 about?
NCT03739372 is a clinical study titled "Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma". This is a 2 strata pilot trial within the Pacific Pediatric Neuro-Oncology Consortium (PNOC). The study will use a new treatment approach based on each patient's tumor gene expression, whole-exome sequencing (WES), targeted panel profile (UCSF 500 gene panel), and RNA-Seq. The current study will te...
What is the current status of trial NCT03739372?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 44 participants. The study started on 2018-11-28. Estimated completion is 2027-01-01.
What conditions does trial NCT03739372 study?
This clinical trial studies the following conditions: Cancer, Glioblastoma, Glioma, Pediatric Cancer, Astrocytoma.
What interventions are being tested in trial NCT03739372?
The interventions under investigation include: Specialized tumor board recommendation (OTHER).
Who is sponsoring clinical trial NCT03739372?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03739372 being conducted?
This trial has 12 study locations across California, District of Columbia, Florida, Illinois, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03739372's enrollment target sits among peer trials
44 449th of 615 higher than 162 of 615 other Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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