Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

ACTIVE NOT RECRUITING NA

Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma

NCT03739372 · View on ClinicalTrials.gov ↗

Study Summary

This is a 2 strata pilot trial within the Pacific Pediatric Neuro-Oncology Consortium (PNOC). The study will use a new treatment approach based on each patient's tumor gene expression, whole-exome sequencing (WES), targeted panel profile (UCSF 500 gene panel), and RNA-Seq. The current study will test the efficacy of such an approach in children with High-grade gliomas HGG.

Interventions

  • OTHER Specialized tumor board recommendation

Study Locations (12)

California

  • University of California, San Diego Rady Children's Hospital — San Diego
  • University of California, San Francisco — San Francisco

District of Columbia

  • Children's National Medical Center — Washington D.C.

Florida

  • University of Florida — Gainesville

Illinois

  • Ann & Robert H. Lurie Children's Hospital of Chicago — Chicago

Maryland

  • Johns Hopkins University — Baltimore

Minnesota

  • Children's Hospitals and Clinics of Minneapolis — Minneapolis

Missouri

  • Washington University — St Louis

Ohio

  • Nationwide Children's Hospital — Columbus

Trial Details

FieldValue
Enrollment Target 44 participants
Start Date 2018-11-28
Est. Completion 2027-01-01
Phase NA

Sponsor

University of California, San Francis

1,574 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03739372

The ClinicalTrials.gov registry entry for NCT03739372 describes a study currently listed as active not recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 44 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Francis, which has 1,574 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 8 conditions, with Cancer appearing as the primary indexed condition, and to 1 intervention — of which Specialized tumor board recommendation is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03739372 reports 12 study locations spanning 11 distinct geographic areas — top geographies include California, District of Columbia, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03739372 about?

NCT03739372 is a clinical study titled "Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma". This is a 2 strata pilot trial within the Pacific Pediatric Neuro-Oncology Consortium (PNOC). The study will use a new treatment approach based on each patient's tumor gene expression, whole-exome sequencing (WES), targeted panel profile (UCSF 500 gene panel), and RNA-Seq. The current study will te...

What is the current status of trial NCT03739372?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 44 participants. The study started on 2018-11-28. Estimated completion is 2027-01-01.

What conditions does trial NCT03739372 study?

This clinical trial studies the following conditions: Cancer, Glioblastoma, Glioma, Pediatric Cancer, Astrocytoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03739372?

The interventions under investigation include: Specialized tumor board recommendation (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03739372?

This trial is sponsored by University of California, San Francis, which has 1,574 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03739372 being conducted?

This trial has 12 study locations across California, District of Columbia, Florida, Illinois, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial