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NCT04614662 · ClinicalTrials.gov registry record · NA

Symptom Screening Linked to Care Pathways

A NA study of Quality of Life and Pediatric Cancer, sponsored by The Hospital for Sick Children.

Completed
Registry status
NA
Development phase
445
Enrollment target
20
Study locations

NCT04614662: Completed NA study of Quality of Life and Pediatric Cancer, sponsored by The Hospital for Sick Children.

NCT04614662 is a NA study of Quality of Life and Pediatric Cancer that has completed, run by The Hospital for Sick Children. The registered enrollment target is 445 participants, roughly in line with the 449-participant average among 107 other Quality of Life trials with a reported enrollment target. The trial reports 20 study locations across 14 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04614662, a NA study of Quality of Life and Pediatric Cancer, has completed, sponsored by The Hospital for Sick Children.

COMPLETED
Registry status
NA
Development phase
445 participants
Enrollment target
20
Study locations

Study Summary

Most children with cancer survive because they are given intensive treatments, but unfortunately, these treatments are associated with distressing symptoms. To address this problem, we developed the Symptom Screening in Pediatrics Tool (SSPedi) so that children receiving cancer treatments can communicate their bothersome symptoms, and Supportive care Prioritization, Assessment and Recommendations for Kids (SPARK), a web-based application that links identified symptoms to supportive care guidelines for symptom management. To establish that these tools improve the lives of children newly diagnosed with cancer, we will conduct a trial that randomizes 20 pediatric cancer institutions and measures the impact of three times weekly symptom screening, symptom feedback to healthcare providers and the development of care pathways for symptom management to improve total symptom burden, fatigue and quality of life.

Primary Outcome

SSPedi measures the degree to which 15 symptoms bothered the participant yesterday or today. Each symptom is scored on a 5-point Likert scale ranging from 0 (not at all bothered) to 4 (extremely bothered). The total score ranges from 0 to 60 where higher numbers indicate more bothersome symptoms. The total SSPedi score is reliable, valid and responsive to change in children with cancer 8-18 years of age.(1)

Conditions Studied

Quality of Life Pediatric Cancer

Interventions

  • BEHAVIORAL SPARK Symptom Screening Linked to Feedback to Providers

Study Locations (20)

Texas

  • Driscoll Children's Hospital - Corpus Christi
  • The University of Texas M. D. Anderson Cancer Center - Houston
  • The University of Texas Health Science Center at San Antonio - San Antonio

California

  • Children's Hospital Los Angeles - Los Angeles
  • The Leland Stanford Junior University - Redwood City

Florida

  • Nemours Children's Health, Jacksonville - Jacksonville
  • Nemours Children's Hospital, Florida - Orlando

Iowa

  • Unity Point Health - Blank Children's Hospital - Des Moines
  • The University of Iowa - Iowa City

New York

  • Roswell Park Comprehensive Cancer Center - Buffalo
  • The Trustees of Columbia University in the City of New York - New York

Arizona

  • Phoenix Children's Hospital - Phoenix

Colorado

  • University of Colorado Denver - Aurora

Connecticut

  • Connecticut Children's Medical Center - Hartford

Trial Details

FieldValue
Enrollment Target 445 participants
Start Date 2021-08-02
Est. Completion 2023-10-25
Phase NA
The Hospital for Sick Children

23 total trials

What the finished NCT04614662 record still lists

NCT04614662 is an interventional study that assigns participants to a tested intervention. The registered 445 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 449-participant average among 107 other Quality of Life trials with a reported enrollment target.

The record links to 2 conditions, with Quality of Life appearing as the primary indexed condition, and to 1 intervention - of which SPARK Symptom Screening Linked to Feedback to Providers is the first listed.

NCT04614662 names 20 study sites across 14 states, led by Texas, California, Florida.

Frequently Asked Questions

What is clinical trial NCT04614662 about?

NCT04614662 is a clinical study titled "Symptom Screening Linked to Care Pathways". Most children with cancer survive because they are given intensive treatments, but unfortunately, these treatments are associated with distressing symptoms. To address this problem, we developed the Symptom Screening in Pediatrics Tool (SSPedi) so that children receiving cancer treatments can commun...

What is the current status of trial NCT04614662?

This trial is currently completed. It is a NA study. The enrollment target is 445 participants. The study started on 2021-08-02. Estimated completion is 2023-10-25.

What conditions does trial NCT04614662 study?

This clinical trial studies the following conditions: Quality of Life, Pediatric Cancer.

What interventions are being tested in trial NCT04614662?

The interventions under investigation include: SPARK Symptom Screening Linked to Feedback to Providers (BEHAVIORAL).

Who is sponsoring clinical trial NCT04614662?

This trial is sponsored by The Hospital for Sick Children, which has 23 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04614662 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Connecticut, Delaware. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Quality of Life

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04614662's enrollment target sits among peer trials

445 14th of 107 higher than 94 of 107 other Quality of Life trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Quality of Life trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT04614662, the US trial registry maintained by the National Library of Medicine. NCT04614662 (mid enrollment · wide site footprint · completed) retrieved and formatted by PlainTrial, see methodology.