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Parkinson Disease clinical trials
135 of 298 indexed Parkinson Disease trials are currently recruiting.
298 US clinical trials · 135 currently recruiting
Parkinson Disease is the subject of 298 registered US clinical trials on ClinicalTrials.gov, 135 of them currently open to new participants. 21 are in Phase 3-4 (later-stage) and 66 in Phase 1-2 (earlier-stage). The most active sponsor is University of Minnesota, running 10 of these trials.
The research picture
Parkinson Disease has 298 registered US clinical trials, 135 of them open to new participants right now, about 45% of the total.
- 135
- recruiting participants now
- 45%
- of trials open to enrollment
- 21
- in Phase 3–4 (later-stage)
- 10
- top sponsor: University of Minnesota
Active & Recent Trials
298 total, page 6 of 6
Continuous Wearable Monitor for the Detection and Release of Freezing of Gait.
HealthPartners Institute
NCT06385392
Responders to Rhythmic Auditory Cueing in Parkinson Disease
Boston University Charles River Campus
NCT05733819
JP-1730 to Treat Parkinson's Disease
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00040209
High-Speed Yoga and Executive Function
University of Miami
NCT04215900
Investigating Central Neurophysiologic Correlates of Non-Motor Symptoms of Parkinson's Disease
University of North Carolina, Chapel Hill
NCT05205772
BUrst vs. Spaced Physical Therapy for Parkinson's Disease: The BUS PT Timing Trial
University of Florida
NCT05180747
Donepezil to Treat Dementia in Parkinson's Disease
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00030979
Transcranial Magnetic Stimulation to Treat Parkinson's Disease
Mark Hallett
NCT00753519
Istradefylline Effect Protocol on Parkinson's Disease Tremor
Georgetown University
NCT05885360
The Impact of Standard Medical Care (Dopamine) and Practice on Postural Motor Learning in Parkinson's Disease
University of Utah
NCT02593812
Evaluation of 123-I Iodobenzovesamicol (IBVM) and SPECT Imaging of Healthy Subjects and Patients With Alzheimer Disease
Institute for Neurodegenerative Disorders
NCT00480701
A Home Program Using Multimodal Sensory Feedback for People With Parkinson Disease
Regis University
NCT04223245
Combining VNS With PT Interventions for Individuals With PD
University of Alabama at Birmingham
NCT05871151
The Efficacy of a Remote Cognitive Remediation Therapy (CRT) Program on Parkinson's Disease
New York Institute of Technology
NCT04955275
Multiple-dose Trial to Determine the Clinical Bioequivalence Between Tavapadon Tablets in Participants With Parkinson's Disease
Cerevel Therapeutics
NCT05610189
Treatment of REM Sleep Behavior Disorder (RBD) With Sodium Oxybate
Stanford University
NCT04006925
Moving Mindfully for Freezing of Gait
Washington University School of Medicine
NCT05923229
BTRX-246040 Study in Participants With Parkinson's Disease With Motor Fluctuations
BlackThorn Therapeutics
NCT03608371
Randomized, Double-Blind Clinical Trial for Parkinson's Disease (Early and Moderate)
Hope Biosciences Research Foundation
NCT04928287
Buspirone in Parkinson's Disease
University of Rochester
NCT02803749
The Effects of Auditory Cues on Gait Mechanics in Parkinson's Disease
University of North Carolina, Chapel Hill
NCT03253965
Community Exercise for Fall Risk in PD
Idaho State University
NCT05940077
Proprioception and Meditation
University of Miami
NCT03079817
In Vivo Imaging of Therapeutic Electric Current Flow
University of Florida
NCT02453763
Brain Perfusion & Oxygenation in Parkinson's Disease With NOH
William Ondo, MD
NCT03229174
Evaluation of [18F]MK-9470 as a Brain Tracer of Cannabinoid-1 Receptor in Parkinson's Disease and Healthy Subjects
Institute for Neurodegenerative Disorders
NCT01462708
Yoga for Anxiety in Adults
Rutgers, The State University of New Jersey
NCT04240899
Prospective Memory Training in Parkinson Disease
Washington University School of Medicine
NCT03582670
Treatment Protocol for PD Fatigue Management With CBT
New York Institute of Technology
NCT03747848
In-home Cycling for Individuals With PD: Effectiveness
University of Wisconsin, Madison
NCT06616948
A Pilot Study of Terazosin for Parkinson's Disease
Jordan Schultz
NCT03905811
Physiology, Imaging and Modeling of Essential Tremor
University of Florida
NCT03811405
Effects of Protective Step Training on Proactive and Reactive Motor Adaptations in Parkinson's Disease Patients
Arizona State University
NCT07399613
Analysis and Suppression of Tremor During Grasp Using Ultrasound Imaging and Electrical Stimulation
North Carolina State University
NCT05308368
Wearable Movement Sensors for Assessing Motor Impairments and Dyskinesias in Parkinson Disease
University of Rochester
NCT01648803
Effects of Nordic Walking Exercise on Gait, Motor/Non-motor Symptoms, and Exercise Biomarkers in Parkinson's Disease
Grand Valley State University
NCT04237025
Osteopathic Manual Treatment Parkinson's Disease and Truncal Dystonia
New York Institute of Technology
NCT03307161
Bracing for Walking in Parkinson's Disease
University of Texas Southwestern Medical Center
NCT03192046
A Comparison of an Implanted Neuroprosthesis With Sensory Training for Improving Airway Protection in Chronic Dysphagia
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00376506
Emotional Prosody Treatment in Parkinson's
VA Office of Research and Development
NCT01956266
BIG for Life: a Pilot Study
State University of New York - Upstate Medical University
NCT04090476
FitMi PD Home Therapy for Parkinson's Disease
Flint Rehabilitation Devices
NCT05655377
Effect of GOCOVRI (Amantadine, Extended Release Capsules) on Gait in Parkinson's Disease
Oregon Health and Science University
NCT04387773
Scalar Closed Loop Intraoperative Study
Dennis Turner, M.D.
NCT03270657
Convection Enhanced Delivery of CSF in DBS for Parkinson's
Jeff Elias, MD
NCT03540134
Priming Through Timing. Using Opposing Strategies to Enhance Motor Learning for Individuals With Parkinson's Disease
University of North Carolina, Chapel Hill
NCT03660605
Research Involving Subjects With Parkinson's Disease, Alzheimer Disease and Healthy Controls
Institute for Neurodegenerative Disorders
NCT01461109
Impact of Exercise in Parkinson's Disease
University of Alabama at Birmingham
NCT03495193
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 31 |
| Phase 2 | 35 |
| Phase 3 | 8 |
| Phase 4 | 13 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Parkinson Disease Trial Landscape
298 indexed Parkinson Disease studies · 135 recruiting (45%).
Phase mix: 21 late (III/IV) vs 66 early (I/II).
Top sponsor: University of Minnesota (10 trials), 9 others listed. 48 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Parkinson Disease?
PlainTrial tracks 298 US clinical trials for Parkinson Disease, of which 135 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Parkinson Disease?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.