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Parkinson Disease: early-phase trial registry
135 of 298 indexed Parkinson Disease trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #31 of 28,707 conditions by registered trial count.
298 US clinical trials · 135 currently recruiting · #31 of 28,707 conditions by registered trial count
Parkinson Disease: 298 US clinical trials tracked, 135 recruiting.
Parkinson Disease is the subject of 298 registered US clinical trials on ClinicalTrials.gov, 135 of them currently open to new participants. 21 are in Phase 3-4 (later-stage) and 66 in Phase 1-2 (earlier-stage). The most active sponsor is University of Minnesota, running 10 of these trials.
Enrollment posture brief
Registry condition parkinson-disease
OPEN 135 | RECR 45% | LATE 21 | EARLY 66 | RANK #31 | SPON 10
Volume-matched condition peers
Nearest open-share peer: Gastric Cancer (45% recruiting · 159 trials)
Parkinson Disease lists 135 open slots (45% of 298 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Parkinson Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Parkinson Disease is recruiting above its size-band peers.
135 of 298 indexed trials (45.3%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Parkinson Disease trials is spread across many organizations.
University of Minnesota accounts for 10 of 298 trials (3.4%). 165 distinct sponsors appear on at least one study for this condition label.
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Most Parkinson Disease trials plan to enrol fewer than 100 people.
Median target enrolment is 55 among the 298 trials that report a genuine target (sentinel values excluded). 207 of those (69.5%) plan for fewer than 100 participants.
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Parkinson Disease research is mostly interventional.
226 interventional and 72 observational studies make up this index (75.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
298 total, page 6 of 6
Continuous Wearable Monitor for the Detection and Release of Freezing of Gait.
HealthPartners Institute
NCT06385392
Responders to Rhythmic Auditory Cueing in Parkinson Disease
Boston University Charles River Campus
NCT05733819
JP-1730 to Treat Parkinson's Disease
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00040209
High-Speed Yoga and Executive Function
University of Miami
NCT04215900
Investigating Central Neurophysiologic Correlates of Non-Motor Symptoms of Parkinson's Disease
University of North Carolina, Chapel Hill
NCT05205772
BUrst vs. Spaced Physical Therapy for Parkinson's Disease: The BUS PT Timing Trial
University of Florida
NCT05180747
Donepezil to Treat Dementia in Parkinson's Disease
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00030979
Transcranial Magnetic Stimulation to Treat Parkinson's Disease
Mark Hallett
NCT00753519
Istradefylline Effect Protocol on Parkinson's Disease Tremor
Georgetown University
NCT05885360
The Impact of Standard Medical Care (Dopamine) and Practice on Postural Motor Learning in Parkinson's Disease
University of Utah
NCT02593812
Evaluation of 123-I Iodobenzovesamicol (IBVM) and SPECT Imaging of Healthy Subjects and Patients With Alzheimer Disease
Institute for Neurodegenerative Disorders
NCT00480701
A Home Program Using Multimodal Sensory Feedback for People With Parkinson Disease
Regis University
NCT04223245
Combining VNS With PT Interventions for Individuals With PD
University of Alabama at Birmingham
NCT05871151
The Efficacy of a Remote Cognitive Remediation Therapy (CRT) Program on Parkinson's Disease
New York Institute of Technology
NCT04955275
Multiple-dose Trial to Determine the Clinical Bioequivalence Between Tavapadon Tablets in Participants With Parkinson's Disease
Cerevel Therapeutics
NCT05610189
Treatment of REM Sleep Behavior Disorder (RBD) With Sodium Oxybate
Stanford University
NCT04006925
Moving Mindfully for Freezing of Gait
Washington University School of Medicine
NCT05923229
BTRX-246040 Study in Participants With Parkinson's Disease With Motor Fluctuations
BlackThorn Therapeutics
NCT03608371
Randomized, Double-Blind Clinical Trial for Parkinson's Disease (Early and Moderate)
Hope Biosciences Research Foundation
NCT04928287
Buspirone in Parkinson's Disease
University of Rochester
NCT02803749
The Effects of Auditory Cues on Gait Mechanics in Parkinson's Disease
University of North Carolina, Chapel Hill
NCT03253965
Community Exercise for Fall Risk in PD
Idaho State University
NCT05940077
Proprioception and Meditation
University of Miami
NCT03079817
In Vivo Imaging of Therapeutic Electric Current Flow
University of Florida
NCT02453763
Brain Perfusion & Oxygenation in Parkinson's Disease With NOH
William Ondo, MD
NCT03229174
Evaluation of [18F]MK-9470 as a Brain Tracer of Cannabinoid-1 Receptor in Parkinson's Disease and Healthy Subjects
Institute for Neurodegenerative Disorders
NCT01462708
Yoga for Anxiety in Adults
Rutgers, The State University of New Jersey
NCT04240899
Prospective Memory Training in Parkinson Disease
Washington University School of Medicine
NCT03582670
Treatment Protocol for PD Fatigue Management With CBT
New York Institute of Technology
NCT03747848
In-home Cycling for Individuals With PD: Effectiveness
University of Wisconsin, Madison
NCT06616948
A Pilot Study of Terazosin for Parkinson's Disease
Jordan Schultz
NCT03905811
Physiology, Imaging and Modeling of Essential Tremor
University of Florida
NCT03811405
Effects of Protective Step Training on Proactive and Reactive Motor Adaptations in Parkinson's Disease Patients
Arizona State University
NCT07399613
Analysis and Suppression of Tremor During Grasp Using Ultrasound Imaging and Electrical Stimulation
North Carolina State University
NCT05308368
Wearable Movement Sensors for Assessing Motor Impairments and Dyskinesias in Parkinson Disease
University of Rochester
NCT01648803
Effects of Nordic Walking Exercise on Gait, Motor/Non-motor Symptoms, and Exercise Biomarkers in Parkinson's Disease
Grand Valley State University
NCT04237025
Osteopathic Manual Treatment Parkinson's Disease and Truncal Dystonia
New York Institute of Technology
NCT03307161
Bracing for Walking in Parkinson's Disease
University of Texas Southwestern Medical Center
NCT03192046
A Comparison of an Implanted Neuroprosthesis With Sensory Training for Improving Airway Protection in Chronic Dysphagia
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00376506
Emotional Prosody Treatment in Parkinson's
VA Office of Research and Development
NCT01956266
BIG for Life: a Pilot Study
State University of New York - Upstate Medical University
NCT04090476
FitMi PD Home Therapy for Parkinson's Disease
Flint Rehabilitation Devices
NCT05655377
Effect of GOCOVRI (Amantadine, Extended Release Capsules) on Gait in Parkinson's Disease
Oregon Health and Science University
NCT04387773
Scalar Closed Loop Intraoperative Study
Dennis Turner, M.D.
NCT03270657
Convection Enhanced Delivery of CSF in DBS for Parkinson's
Jeff Elias, MD
NCT03540134
Priming Through Timing. Using Opposing Strategies to Enhance Motor Learning for Individuals With Parkinson's Disease
University of North Carolina, Chapel Hill
NCT03660605
Research Involving Subjects With Parkinson's Disease, Alzheimer Disease and Healthy Controls
Institute for Neurodegenerative Disorders
NCT01461109
Impact of Exercise in Parkinson's Disease
University of Alabama at Birmingham
NCT03495193
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 31 |
| Phase 2 | 35 |
| Phase 3 | 8 |
| Phase 4 | 13 |
Top Sponsors
Named interventions
Most-linked intervention names on Parkinson Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Parkinson Disease trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Parkinson Disease page
298 registered trials, 135 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 135 Parkinson Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Minnesota sponsors the most Parkinson Disease trials on record, review their full trial history before evaluating a specific study. See University of Minnesota's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Parkinson Disease condition card totals 298 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.