Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 135 recruiting now official registry

Parkinson Disease clinical trials

135 of 298 indexed Parkinson Disease trials are currently recruiting.

298 US clinical trials · 135 currently recruiting

Parkinson Disease is the subject of 298 registered US clinical trials on ClinicalTrials.gov, 135 of them currently open to new participants. 21 are in Phase 3-4 (later-stage) and 66 in Phase 1-2 (earlier-stage). The most active sponsor is University of Minnesota, running 10 of these trials.

The research picture

Parkinson Disease has 298 registered US clinical trials, 135 of them open to new participants right now, about 45% of the total.

135
recruiting participants now
45%
of trials open to enrollment
21
in Phase 3–4 (later-stage)
10
top sponsor: University of Minnesota
Phase 131Phase 235Phase 38Phase 413

Active & Recent Trials

298 total, page 6 of 6

COMPLETED 31 participants

Continuous Wearable Monitor for the Detection and Release of Freezing of Gait.

HealthPartners Institute

NCT06385392

COMPLETED Phase 1 31 participants

Responders to Rhythmic Auditory Cueing in Parkinson Disease

Boston University Charles River Campus

NCT05733819

COMPLETED Phase 2 30 participants

JP-1730 to Treat Parkinson's Disease

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00040209

COMPLETED NA 30 participants

High-Speed Yoga and Executive Function

University of Miami

NCT04215900

COMPLETED NA 30 participants

Investigating Central Neurophysiologic Correlates of Non-Motor Symptoms of Parkinson's Disease

University of North Carolina, Chapel Hill

NCT05205772

COMPLETED NA 30 participants

BUrst vs. Spaced Physical Therapy for Parkinson's Disease: The BUS PT Timing Trial

University of Florida

NCT05180747

COMPLETED Phase 4 28 participants

Donepezil to Treat Dementia in Parkinson's Disease

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00030979

COMPLETED Phase 1 28 participants

Transcranial Magnetic Stimulation to Treat Parkinson's Disease

Mark Hallett

NCT00753519

COMPLETED Phase 4 27 participants

Istradefylline Effect Protocol on Parkinson's Disease Tremor

Georgetown University

NCT05885360

COMPLETED NA 27 participants

The Impact of Standard Medical Care (Dopamine) and Practice on Postural Motor Learning in Parkinson's Disease

University of Utah

NCT02593812

COMPLETED Phase 2 26 participants

Evaluation of 123-I Iodobenzovesamicol (IBVM) and SPECT Imaging of Healthy Subjects and Patients With Alzheimer Disease

Institute for Neurodegenerative Disorders

NCT00480701

COMPLETED NA 26 participants

A Home Program Using Multimodal Sensory Feedback for People With Parkinson Disease

Regis University

NCT04223245

COMPLETED NA 25 participants

Combining VNS With PT Interventions for Individuals With PD

University of Alabama at Birmingham

NCT05871151

COMPLETED NA 25 participants

The Efficacy of a Remote Cognitive Remediation Therapy (CRT) Program on Parkinson's Disease

New York Institute of Technology

NCT04955275

COMPLETED Phase 1 25 participants

Multiple-dose Trial to Determine the Clinical Bioequivalence Between Tavapadon Tablets in Participants With Parkinson's Disease

Cerevel Therapeutics

NCT05610189

COMPLETED Phase 4 24 participants

Treatment of REM Sleep Behavior Disorder (RBD) With Sodium Oxybate

Stanford University

NCT04006925

COMPLETED NA 24 participants

Moving Mindfully for Freezing of Gait

Washington University School of Medicine

NCT05923229

COMPLETED Phase 2 24 participants

BTRX-246040 Study in Participants With Parkinson's Disease With Motor Fluctuations

BlackThorn Therapeutics

NCT03608371

COMPLETED Phase 2 24 participants

Randomized, Double-Blind Clinical Trial for Parkinson's Disease (Early and Moderate)

Hope Biosciences Research Foundation

NCT04928287

COMPLETED Phase 2 21 participants

Buspirone in Parkinson's Disease

University of Rochester

NCT02803749

COMPLETED NA 21 participants

The Effects of Auditory Cues on Gait Mechanics in Parkinson's Disease

University of North Carolina, Chapel Hill

NCT03253965

COMPLETED NA 20 participants

Community Exercise for Fall Risk in PD

Idaho State University

NCT05940077

COMPLETED NA 20 participants

Proprioception and Meditation

University of Miami

NCT03079817

COMPLETED 17 participants

In Vivo Imaging of Therapeutic Electric Current Flow

University of Florida

NCT02453763

COMPLETED Phase 4 17 participants

Brain Perfusion & Oxygenation in Parkinson's Disease With NOH

William Ondo, MD

NCT03229174

COMPLETED Phase 1 16 participants

Evaluation of [18F]MK-9470 as a Brain Tracer of Cannabinoid-1 Receptor in Parkinson's Disease and Healthy Subjects

Institute for Neurodegenerative Disorders

NCT01462708

COMPLETED NA 16 participants

Yoga for Anxiety in Adults

Rutgers, The State University of New Jersey

NCT04240899

COMPLETED NA 15 participants

Prospective Memory Training in Parkinson Disease

Washington University School of Medicine

NCT03582670

COMPLETED NA 14 participants

Treatment Protocol for PD Fatigue Management With CBT

New York Institute of Technology

NCT03747848

COMPLETED NA 14 participants

In-home Cycling for Individuals With PD: Effectiveness

University of Wisconsin, Madison

NCT06616948

COMPLETED Phase 1 13 participants

A Pilot Study of Terazosin for Parkinson's Disease

Jordan Schultz

NCT03905811

COMPLETED NA 12 participants

Physiology, Imaging and Modeling of Essential Tremor

University of Florida

NCT03811405

COMPLETED NA 12 participants

Effects of Protective Step Training on Proactive and Reactive Motor Adaptations in Parkinson's Disease Patients

Arizona State University

NCT07399613

COMPLETED NA 12 participants

Analysis and Suppression of Tremor During Grasp Using Ultrasound Imaging and Electrical Stimulation

North Carolina State University

NCT05308368

COMPLETED 12 participants

Wearable Movement Sensors for Assessing Motor Impairments and Dyskinesias in Parkinson Disease

University of Rochester

NCT01648803

COMPLETED NA 12 participants

Effects of Nordic Walking Exercise on Gait, Motor/Non-motor Symptoms, and Exercise Biomarkers in Parkinson's Disease

Grand Valley State University

NCT04237025

COMPLETED NA 10 participants

Osteopathic Manual Treatment Parkinson's Disease and Truncal Dystonia

New York Institute of Technology

NCT03307161

COMPLETED NA 10 participants

Bracing for Walking in Parkinson's Disease

University of Texas Southwestern Medical Center

NCT03192046

COMPLETED Phase 2 10 participants

A Comparison of an Implanted Neuroprosthesis With Sensory Training for Improving Airway Protection in Chronic Dysphagia

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00376506

COMPLETED NA 10 participants

Emotional Prosody Treatment in Parkinson's

VA Office of Research and Development

NCT01956266

COMPLETED NA 10 participants

BIG for Life: a Pilot Study

State University of New York - Upstate Medical University

NCT04090476

COMPLETED NA 9 participants

FitMi PD Home Therapy for Parkinson's Disease

Flint Rehabilitation Devices

NCT05655377

COMPLETED Phase 4 8 participants

Effect of GOCOVRI (Amantadine, Extended Release Capsules) on Gait in Parkinson's Disease

Oregon Health and Science University

NCT04387773

COMPLETED NA 5 participants

Scalar Closed Loop Intraoperative Study

Dennis Turner, M.D.

NCT03270657

COMPLETED NA 4 participants

Convection Enhanced Delivery of CSF in DBS for Parkinson's

Jeff Elias, MD

NCT03540134

COMPLETED NA 4 participants

Priming Through Timing. Using Opposing Strategies to Enhance Motor Learning for Individuals With Parkinson's Disease

University of North Carolina, Chapel Hill

NCT03660605

COMPLETED Phase 1 4 participants

Research Involving Subjects With Parkinson's Disease, Alzheimer Disease and Healthy Controls

Institute for Neurodegenerative Disorders

NCT01461109

COMPLETED NA 4 participants

Impact of Exercise in Parkinson's Disease

University of Alabama at Birmingham

NCT03495193

← Previous Page 6 of 6

Reading the Parkinson Disease Trial Landscape

298 indexed Parkinson Disease studies · 135 recruiting (45%).

Phase mix: 21 late (III/IV) vs 66 early (I/II).

Top sponsor: University of Minnesota (10 trials), 9 others listed. 48 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Parkinson Disease?

PlainTrial tracks 298 US clinical trials for Parkinson Disease, of which 135 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Parkinson Disease?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.