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NCT03229174 · ClinicalTrials.gov registry record · Phase 4

Brain Perfusion & Oxygenation in Parkinson's Disease With NOH

A Phase 4 study of Parkinson Disease and Neurogenic Orthostatic Hypotension, sponsored by William Ondo, MD.

Completed
Registry status
Phase 4
Development phase
17
Enrollment target
1
Study location

NCT03229174 is a Phase 4 study of Parkinson Disease and Neurogenic Orthostatic Hypotension that has completed, run by William Ondo, MD. The registered enrollment target is 17 participants, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03229174, a Phase 4 study of Parkinson Disease and Neurogenic Orthostatic Hypotension, has completed, sponsored by William Ondo, MD.

COMPLETED
Registry status
Phase 4
Development phase
17 participants
Enrollment target
1
Study location

Study Summary

This is a double blind placebo controlled trial in Parkinson's disease (PD) patients with neurogenic orthostatic hypotension (NOH). Investigators hypothesize that the study drug (droxidopa) may improve cerebral perfusion more robustly than systemic BP, possibly by direct action within the CNS vasculature. This study is designed to determine if droxidopa improves cerebral perfusion measures in PD patients with NOH, in addition to peripheral BP measures and subjective responses.

Conditions Studied

Parkinson Disease Neurogenic Orthostatic Hypotension

Interventions

  • DRUG Placebo
  • DRUG Droxidopa

Study Locations (1)

Texas

  • Houston Methodist Hospital - Houston

Trial Details

FieldValue
Enrollment Target 17 participants
Start Date 2018-08-23
Est. Completion 2022-02-02
Phase Phase 4

Sponsor

William Ondo, MD

2 total trials

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What the Registry Record Tells You About NCT03229174

The ClinicalTrials.gov registry entry for NCT03229174 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 17 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (100% lower). The listed sponsor is William Ondo, MD, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Parkinson Disease appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT03229174 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT03229174 about?

NCT03229174 is a clinical study titled "Brain Perfusion & Oxygenation in Parkinson's Disease With NOH". This is a double blind placebo controlled trial in Parkinson's disease (PD) patients with neurogenic orthostatic hypotension (NOH). Investigators hypothesize that the study drug (droxidopa) may improve cerebral perfusion more robustly than systemic BP, possibly by direct action within the CNS vascul...

What is the current status of trial NCT03229174?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 17 participants. The study started on 2018-08-23. Estimated completion is 2022-02-02.

What conditions does trial NCT03229174 study?

This clinical trial studies the following conditions: Parkinson Disease, Neurogenic Orthostatic Hypotension.

What interventions are being tested in trial NCT03229174?

The interventions under investigation include: Placebo (DRUG), Droxidopa (DRUG).

Who is sponsoring clinical trial NCT03229174?

This trial is sponsored by William Ondo, MD, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03229174 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.