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Parkinson Disease clinical trials
135 of 298 indexed Parkinson Disease trials are currently recruiting.
298 US clinical trials · 135 currently recruiting
Parkinson Disease is the subject of 298 registered US clinical trials on ClinicalTrials.gov, 135 of them currently open to new participants. 21 are in Phase 3-4 (later-stage) and 66 in Phase 1-2 (earlier-stage). The most active sponsor is University of Minnesota, running 10 of these trials.
The research picture
Parkinson Disease has 298 registered US clinical trials, 135 of them open to new participants right now, about 45% of the total.
- 135
- recruiting participants now
- 45%
- of trials open to enrollment
- 21
- in Phase 3–4 (later-stage)
- 10
- top sponsor: University of Minnesota
Active & Recent Trials
298 total, page 5 of 6
Open-label, Long-term Safety Extension Study of AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias
Novartis Pharmaceuticals
NCT01491932
Study in Parkinson's Disease of Exercise
University of Colorado, Denver
NCT01506479
Randomized Study of the Effects of Glucose on Cognition in Healthy Young and Elderly People and Parkinson's Disease Patients
National Institute of Mental Health (NIMH)
NCT00004451
Fox BioNet Project: LRRK2-002
Michael J. Fox Foundation for Parkinson's Research
NCT03545425
Driving Performance of People With Parkinson's Using Autonomous In-Vehicle Technologies
University of Florida
NCT04660500
A Study to Investigate a New Treatment in Patients With Parkinson's Disease
Tools4Patient
NCT03407378
Movement-2-Music: Lakeshore Examination of Activity, Disability, and Exercise Response Study
University of Alabama at Birmingham
NCT03797378
Effects of Aerobic Exercise in Parkinson's Disease
US Department of Veterans Affairs
NCT00784563
The Benefits of Nature for Mood and Cognition in Persons With and Without Parkinson's Disease
Boston University Charles River Campus
NCT06483126
GM1 Ganglioside Effects on Parkinson's Disease
Thomas Jefferson University
NCT00037830
Biomarkers of Risk of Parkinson Disease
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00775853
Quantitative Mapping of Substantia Nigra Iron in Parkinson's Disease (Stages I-IV, REM Sleep Behavior Disorder) and Controls
Weill Medical College of Cornell University
NCT03675282
PROGENI (Parkinson's Research: The Organized Genetics Initiative) Family Study of LRRK2 (Leucine-rich Repeat Kinase 2)
Indiana University
NCT01536821
Transcranial Magnetic Stimulation in Parkinson's Disease
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00023062
A Study to Assess the Safety of GRF6021 Infusions in Subjects With Parkinson's Disease and Cognitive Impairment
Alkahest
NCT03713957
Behavioral or Solifenacin Therapy for Urinary Symptoms in Parkinson Disease
VA Office of Research and Development
NCT03149809
GentleCath™ for Men Intermittent Catheter With FeelClean™ Technology
ConvaTec
NCT05470751
Visual Spatial Exploration and Art Therapy Intervention in Patients Diagnosed With Parkinson's Disease
NYU Langone Health
NCT03178786
A Study of TAK-071 in People With Parkinson Disease
Takeda
NCT04334317
Brain Networks and Consciousness
University of Texas Southwestern Medical Center
NCT04502550
PD4PD:Partnered Dance for Parkinson Disease
Washington University School of Medicine
NCT01388556
Imaging and Genetic Biomarkers of Parkinson Disease (PD) Onset and Progression in High-risk Families
Institute for Neurodegenerative Disorders
NCT00273351
Safety and Tolerability Study of K0706 in Subjects With Parkinson's Disease
Sun Pharma Advanced Research Company Limited
NCT02970019
Clinical Trial for Parkinson's Disease Using Allogeneic HB-adMSCs (Early and Moderate PD)
Hope Biosciences Research Foundation
NCT04995081
Speech, Linguistic and Acoustic Markers in Parkinson's Disease
University of Massachusetts, Worcester
NCT04273672
Lu AF28996 in Participants With Parkinson's Disease (PD)
H. Lundbeck A/S
NCT04291859
FoxBioNet Pilot Project: SAVE (Synuclein Assay Validation Effort)
Michael J. Fox Foundation for Parkinson's Research
NCT03170063
Physiological Effects of Nutritional Support in Patients With Parkinson's Disease
Thomas Jefferson University
NCT02445651
Dual-task Augmented Reality Treatment for Parkinson's Disease
The Cleveland Clinic
NCT04634331
Pre-Active PD: Looking At Physical Activity Behavior Change in Parkinson's Disease
San Jose State University
NCT05308238
Naltrexone for Impulse Control Disorders in Parkinson's Disease
University of Pennsylvania
NCT01052831
Determining the Microbiota Composition of the Middle Meatus in Parkinson's
Rush University Medical Center
NCT03336697
Emotion Study/Substudy: Flexible Brain Study
University of Florida
NCT03872414
The Influence of Sensory Stimuli on Gait Imagery in Patients With Freezing of Gait
National Institute of Neurological Disorders and Stroke (NINDS)
NCT01071590
Strength Training and Medication Effects in Parkinson Disease Effects on Hypokinesia in Parkinson Disease
University of Utah
NCT00665184
Cognitive Disparities in Parkinson's Disease
Duke University
NCT07262658
Levetiracetam Treatment of L-dopa Induced Dyskinesias
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00076674
Embryonic Dopamine Cell Implants for Parkinson's Disease
University of Colorado, Denver
NCT00038116
Transcutaneous Afferent Patterned Stimulation (TAPS) for Reduction of Parkinson's Disease (PD) Related Action Tremor
Cala Health
NCT05012579
A Study to Assess Pharmacokinetic Profiles of LY03003 and Neupro
Luye Pharma Group
NCT03733561
Investigation of Effects of Delayed Feedback on Non-motor Symptoms in Individuals With Parkinson's Disease
Kessler Foundation
NCT06217484
Unlocking Dystonia From Parkinson's Disease With Directional DBS Technology
University of Alabama at Birmingham
NCT03409120
Golf Instruction Versus Tai Chi for People With Parkinson's Disease
Massachusetts General Hospital
NCT03563807
Protective Step Training in Parkinson's Disease
Arizona State University
NCT03895814
Training and Parkinson's
University of Miami
NCT03434327
Effect of Osteopathic Manipulative Medicine on Parkinson Disease
New York Institute of Technology
NCT02107638
Preparing Patient-Caregiver Dyads with Parkinson's Disease for Future Decision Making
Purdue University
NCT05084209
Treadmill Training in People With Parkinson's Disease
Georgia State University
NCT05239026
Tai Chi for Enhancing Motor and Cognitive Function in Parkinson's Disease
Harvard University Faculty of Medicine
NCT02418780
Intranasal Insulin in Parkinson's Disease
HealthPartners Institute
NCT04251585
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 31 |
| Phase 2 | 35 |
| Phase 3 | 8 |
| Phase 4 | 13 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Parkinson Disease Trial Landscape
298 indexed Parkinson Disease studies · 135 recruiting (45%).
Phase mix: 21 late (III/IV) vs 66 early (I/II).
Top sponsor: University of Minnesota (10 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Parkinson Disease?
PlainTrial tracks 298 US clinical trials for Parkinson Disease, of which 135 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Parkinson Disease?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.