Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Parkinson Disease: early-phase trial registry
135 of 298 indexed Parkinson Disease trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #31 of 28,707 conditions by registered trial count.
298 US clinical trials · 135 currently recruiting · #31 of 28,707 conditions by registered trial count
Parkinson Disease: 298 US clinical trials tracked, 135 recruiting.
Parkinson Disease is the subject of 298 registered US clinical trials on ClinicalTrials.gov, 135 of them currently open to new participants. 21 are in Phase 3-4 (later-stage) and 66 in Phase 1-2 (earlier-stage). The most active sponsor is University of Minnesota, running 10 of these trials.
Enrollment posture brief
Registry condition parkinson-disease
OPEN 135 | RECR 45% | LATE 21 | EARLY 66 | RANK #31 | SPON 10
Volume-matched condition peers
Nearest open-share peer: Gastric Cancer (45% recruiting · 159 trials)
Parkinson Disease lists 135 open slots (45% of 298 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Parkinson Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Parkinson Disease is recruiting above its size-band peers.
135 of 298 indexed trials (45.3%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Parkinson Disease trials is spread across many organizations.
University of Minnesota accounts for 10 of 298 trials (3.4%). 165 distinct sponsors appear on at least one study for this condition label.
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Most Parkinson Disease trials plan to enrol fewer than 100 people.
Median target enrolment is 55 among the 298 trials that report a genuine target (sentinel values excluded). 207 of those (69.5%) plan for fewer than 100 participants.
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Parkinson Disease research is mostly interventional.
226 interventional and 72 observational studies make up this index (75.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
298 total, page 5 of 6
Open-label, Long-term Safety Extension Study of AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias
Novartis Pharmaceuticals
NCT01491932
Study in Parkinson's Disease of Exercise
University of Colorado, Denver
NCT01506479
Randomized Study of the Effects of Glucose on Cognition in Healthy Young and Elderly People and Parkinson's Disease Patients
National Institute of Mental Health (NIMH)
NCT00004451
Fox BioNet Project: LRRK2-002
Michael J. Fox Foundation for Parkinson's Research
NCT03545425
Driving Performance of People With Parkinson's Using Autonomous In-Vehicle Technologies
University of Florida
NCT04660500
A Study to Investigate a New Treatment in Patients With Parkinson's Disease
Tools4Patient
NCT03407378
Movement-2-Music: Lakeshore Examination of Activity, Disability, and Exercise Response Study
University of Alabama at Birmingham
NCT03797378
Effects of Aerobic Exercise in Parkinson's Disease
US Department of Veterans Affairs
NCT00784563
The Benefits of Nature for Mood and Cognition in Persons With and Without Parkinson's Disease
Boston University Charles River Campus
NCT06483126
GM1 Ganglioside Effects on Parkinson's Disease
Thomas Jefferson University
NCT00037830
Biomarkers of Risk of Parkinson Disease
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00775853
Quantitative Mapping of Substantia Nigra Iron in Parkinson's Disease (Stages I-IV, REM Sleep Behavior Disorder) and Controls
Weill Medical College of Cornell University
NCT03675282
PROGENI (Parkinson's Research: The Organized Genetics Initiative) Family Study of LRRK2 (Leucine-rich Repeat Kinase 2)
Indiana University
NCT01536821
Transcranial Magnetic Stimulation in Parkinson's Disease
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00023062
A Study to Assess the Safety of GRF6021 Infusions in Subjects With Parkinson's Disease and Cognitive Impairment
Alkahest
NCT03713957
Behavioral or Solifenacin Therapy for Urinary Symptoms in Parkinson Disease
VA Office of Research and Development
NCT03149809
GentleCath™ for Men Intermittent Catheter With FeelClean™ Technology
ConvaTec
NCT05470751
Visual Spatial Exploration and Art Therapy Intervention in Patients Diagnosed With Parkinson's Disease
NYU Langone Health
NCT03178786
A Study of TAK-071 in People With Parkinson Disease
Takeda
NCT04334317
Brain Networks and Consciousness
University of Texas Southwestern Medical Center
NCT04502550
PD4PD:Partnered Dance for Parkinson Disease
Washington University School of Medicine
NCT01388556
Imaging and Genetic Biomarkers of Parkinson Disease (PD) Onset and Progression in High-risk Families
Institute for Neurodegenerative Disorders
NCT00273351
Safety and Tolerability Study of K0706 in Subjects With Parkinson's Disease
Sun Pharma Advanced Research Company Limited
NCT02970019
Clinical Trial for Parkinson's Disease Using Allogeneic HB-adMSCs (Early and Moderate PD)
Hope Biosciences Research Foundation
NCT04995081
Speech, Linguistic and Acoustic Markers in Parkinson's Disease
University of Massachusetts, Worcester
NCT04273672
Lu AF28996 in Participants With Parkinson's Disease (PD)
H. Lundbeck A/S
NCT04291859
FoxBioNet Pilot Project: SAVE (Synuclein Assay Validation Effort)
Michael J. Fox Foundation for Parkinson's Research
NCT03170063
Physiological Effects of Nutritional Support in Patients With Parkinson's Disease
Thomas Jefferson University
NCT02445651
Dual-task Augmented Reality Treatment for Parkinson's Disease
The Cleveland Clinic
NCT04634331
Pre-Active PD: Looking At Physical Activity Behavior Change in Parkinson's Disease
San Jose State University
NCT05308238
Naltrexone for Impulse Control Disorders in Parkinson's Disease
University of Pennsylvania
NCT01052831
Determining the Microbiota Composition of the Middle Meatus in Parkinson's
Rush University Medical Center
NCT03336697
Emotion Study/Substudy: Flexible Brain Study
University of Florida
NCT03872414
The Influence of Sensory Stimuli on Gait Imagery in Patients With Freezing of Gait
National Institute of Neurological Disorders and Stroke (NINDS)
NCT01071590
Strength Training and Medication Effects in Parkinson Disease Effects on Hypokinesia in Parkinson Disease
University of Utah
NCT00665184
Cognitive Disparities in Parkinson's Disease
Duke University
NCT07262658
Levetiracetam Treatment of L-dopa Induced Dyskinesias
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00076674
Embryonic Dopamine Cell Implants for Parkinson's Disease
University of Colorado, Denver
NCT00038116
Transcutaneous Afferent Patterned Stimulation (TAPS) for Reduction of Parkinson's Disease (PD) Related Action Tremor
Cala Health
NCT05012579
A Study to Assess Pharmacokinetic Profiles of LY03003 and Neupro
Luye Pharma Group
NCT03733561
Investigation of Effects of Delayed Feedback on Non-motor Symptoms in Individuals With Parkinson's Disease
Kessler Foundation
NCT06217484
Unlocking Dystonia From Parkinson's Disease With Directional DBS Technology
University of Alabama at Birmingham
NCT03409120
Golf Instruction Versus Tai Chi for People With Parkinson's Disease
Massachusetts General Hospital
NCT03563807
Protective Step Training in Parkinson's Disease
Arizona State University
NCT03895814
Training and Parkinson's
University of Miami
NCT03434327
Effect of Osteopathic Manipulative Medicine on Parkinson Disease
New York Institute of Technology
NCT02107638
Preparing Patient-Caregiver Dyads with Parkinson's Disease for Future Decision Making
Purdue University
NCT05084209
Treadmill Training in People With Parkinson's Disease
Georgia State University
NCT05239026
Tai Chi for Enhancing Motor and Cognitive Function in Parkinson's Disease
Harvard University Faculty of Medicine
NCT02418780
Intranasal Insulin in Parkinson's Disease
HealthPartners Institute
NCT04251585
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 31 |
| Phase 2 | 35 |
| Phase 3 | 8 |
| Phase 4 | 13 |
Top Sponsors
Named interventions
Most-linked intervention names on Parkinson Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Parkinson Disease trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Parkinson Disease page
298 registered trials, 135 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 135 Parkinson Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Minnesota sponsors the most Parkinson Disease trials on record, review their full trial history before evaluating a specific study. See University of Minnesota's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Parkinson Disease condition card totals 298 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.