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NCT05308368 · ClinicalTrials.gov registry record · NA
Analysis and Suppression of Tremor During Grasp Using Ultrasound Imaging and Electrical Stimulation
A NA study of Parkinson Disease and Essential Tremor, sponsored by North Carolina State University.
- Completed
- Registry status
- NA
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT05308368: Completed NA study of Parkinson Disease and Essential Tremor, sponsored by North Carolina State University.
NCT05308368 is a NA study of Parkinson Disease and Essential Tremor that has completed, run by North Carolina State University. The registered enrollment target is 12 participants, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05308368, a NA study of Parkinson Disease and Essential Tremor, has completed, sponsored by North Carolina State University.
- COMPLETED
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
Individuals experiencing tremors face difficulty performing activities of daily living caused by involuntary oscillation of the muscles in the hands and arms. Current solutions to help suppress tremors include medication, surgery, assistive devices and lifestyle change. However, each of these has a drawback of its own including cost and unwanted side effects. Aside from the solutions listed, it has been shown that functional electrical stimulation (FES) is a possible solution to help suppress tremor. Additionally, FES can be combined with different technologies including accelerometers, gyroscopes and motion capture to develop a closed loop system for tremor suppression. However, this has drawbacks including signal interference and the need for multiple sensor to fully classify the tremor. Ultrasound imaging solves some of these issues because it can provide a direct visualization of hand muscles that contribute to tremor. This study will focus on detecting characterizing and differentiating tremors from voluntary hand motion using ultrasound imaging. The results obtained from this study will help design FES-based tremor-suppression techniques in the future. This study will target both subjects with different tremor disorders and able bodied subjects.
Primary Outcome
The investigators will use ultrasound features collected on participants to develop novel models for tremor that can accurately predict the joint position. The joint position measured by the IMU will used as a benchmark and the root mean squared error (RMSE \[Deg.\]) between the model's predicted joint angle and the true angle will be used as a metric. A higher RMSE (in the scale of 0-100%) implies lower model accuracy.
Conditions Studied
Interventions
- DEVICE Ultrasound Imaging
- DEVICE Electromyography
- DEVICE Inertial Measurement Units (IMU)
- DEVICE Functional Electrical Stimulation (FES)
Study Locations (1)
North Carolina
- Engineering Building III - Raleigh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2021-04-11 |
| Est. Completion | 2025-07-31 |
| Phase | NA |
What the finished NCT05308368 record still lists
NCT05308368 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (100% lower).
The record links to 2 conditions, with Parkinson Disease appearing as the primary indexed condition, and to 4 interventions - of which Ultrasound Imaging is the first listed.
NCT05308368 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT05308368 about?
NCT05308368 is a clinical study titled "Analysis and Suppression of Tremor During Grasp Using Ultrasound Imaging and Electrical Stimulation". Individuals experiencing tremors face difficulty performing activities of daily living caused by involuntary oscillation of the muscles in the hands and arms. Current solutions to help suppress tremors include medication, surgery, assistive devices and lifestyle change. However, each of these has a ...
What is the current status of trial NCT05308368?
This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2021-04-11. Estimated completion is 2025-07-31.
What conditions does trial NCT05308368 study?
This clinical trial studies the following conditions: Parkinson Disease, Essential Tremor.
What interventions are being tested in trial NCT05308368?
The interventions under investigation include: Ultrasound Imaging (DEVICE), Electromyography (DEVICE), Inertial Measurement Units (IMU) (DEVICE), Functional Electrical Stimulation (FES) (DEVICE).
Who is sponsoring clinical trial NCT05308368?
This trial is sponsored by North Carolina State University, which has 19 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05308368 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Where NCT05308368's enrollment target sits among peer trials
12 268th of 297 higher than 24 of 297 other Parkinson Disease trials
participants (enrollment target), bucketed by value
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