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NCT05205772 · ClinicalTrials.gov registry record · NA

Investigating Central Neurophysiologic Correlates of Non-Motor Symptoms of Parkinson's Disease

A NA study of Depression and Parkinson Disease, sponsored by University of North Carolina, Chapel Hill.

Completed
Registry status
NA
Development phase
30
Enrollment target
1
Study location

NCT05205772 is a NA study of Depression and Parkinson Disease that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 30 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05205772, a NA study of Depression and Parkinson Disease, has completed, sponsored by University of North Carolina, Chapel Hill.

COMPLETED
Registry status
NA
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

This is a randomized, single-blinded, triple crossover study focused on determining the feasibility of using transcranial magnetic stimulation (TMS) for treatment of Parkinson's disease related autonomic dysfunction and depression. Participants will undergo TMS to three brain regions: medial prefrontal cortex (mPFC) (experimental site), dorsolateral prefrontal cortex (DLPFC) (alternative experimental site), or primary sensory cortex (S1) (control site) in a triple crossover design. Participants will complete symptom questionnaires, neurologic examination and cognitive assessments, and orthostatic vital signs recording before and after each brain stimulation session.

Interventions

  • DEVICE transcranial magnetic stimulation

Study Locations (1)

North Carolina

  • University of North Carolina School of Medicine - Chapel Hill

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2022-02-01
Est. Completion 2024-07-30
Phase NA

What the Registry Record Tells You About NCT05205772

The ClinicalTrials.gov registry entry for NCT05205772 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 786-participant average among 679 other Depression trials with a reported enrollment target (96% lower). The listed sponsor is University of North Carolina, Chapel Hill, which has 1,109 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Depression appearing as the primary indexed condition, and to 1 intervention - of which transcranial magnetic stimulation is the first listed.

NCT05205772 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.

Frequently Asked Questions

What is clinical trial NCT05205772 about?

NCT05205772 is a clinical study titled "Investigating Central Neurophysiologic Correlates of Non-Motor Symptoms of Parkinson's Disease". This is a randomized, single-blinded, triple crossover study focused on determining the feasibility of using transcranial magnetic stimulation (TMS) for treatment of Parkinson's disease related autonomic dysfunction and depression. Participants will undergo TMS to three brain regions: medial prefron...

What is the current status of trial NCT05205772?

This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2022-02-01. Estimated completion is 2024-07-30.

What conditions does trial NCT05205772 study?

This clinical trial studies the following conditions: Depression, Parkinson Disease, Autonomic Dysfunction.

What interventions are being tested in trial NCT05205772?

The interventions under investigation include: transcranial magnetic stimulation (DEVICE).

Who is sponsoring clinical trial NCT05205772?

This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05205772 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.