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NCT03336697 · ClinicalTrials.gov registry record
Determining the Microbiota Composition of the Middle Meatus in Parkinson's
A clinical trial of Parkinson Disease, sponsored by Rush University Medical Center.
- Completed
- Registry status
- 48
- Enrollment target
- 1
- Study location
NCT03336697: Completed study of Parkinson Disease, sponsored by Rush University Medical Center.
NCT03336697 is a study of Parkinson Disease that has completed, run by Rush University Medical Center. The registered enrollment target is 48 participants, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03336697, a study of Parkinson Disease, has completed, sponsored by Rush University Medical Center.
- COMPLETED
- Registry status
- 48 participants
- Enrollment target
- 1
- Study location
Study Summary
The exact cause of PD remains unknown, but current theories suggest that it results from a combination of hereditary or genetic factors (i.e. family traits ) and exposure to unknown substances in the environment. The purpose of this study is to investigate whether toxins produced by bacteria that live within the nasal canal (nose) and the intestines of people with PD might have a role in causing the disease. The investigators in this study would like to look at the types of bacteria that live in the nasal canals and intestines of PD subjects and compare them with those of subjects who do not have PD.
Primary Outcome
For microbiome analysis, in silico community functional predictions will be performed using PICRUSt (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) and significant differences in Kyoto Encyclopedia of Genes and Genomes (KEGG) ortholog (KO) abundances between groups will be identified. "proinflammatory" and "anti-inflammatory" bacteria taxa will be classified and differences in inflammatory metabolite abundance will be compared.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Nasal swab
Study Locations (1)
Illinois
- Rush University Medical Center - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2017-07-01 |
| Est. Completion | 2019-09-10 |
What the finished NCT03336697 record still lists
NCT03336697 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Parkinson Disease appearing as the primary indexed condition, and to 1 intervention - of which Nasal swab is the first listed.
NCT03336697 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT03336697 about?
NCT03336697 is a clinical study titled "Determining the Microbiota Composition of the Middle Meatus in Parkinson's". The exact cause of PD remains unknown, but current theories suggest that it results from a combination of hereditary or genetic factors (i.e. family traits ) and exposure to unknown substances in the environment. The purpose of this study is to investigate whether toxins produced by bacteria that li...
What is the current status of trial NCT03336697?
This trial is currently completed. The enrollment target is 48 participants. The study started on 2017-07-01. Estimated completion is 2019-09-10.
What conditions does trial NCT03336697 study?
This clinical trial studies the following conditions: Parkinson Disease.
What interventions are being tested in trial NCT03336697?
The interventions under investigation include: Nasal swab (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT03336697?
This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03336697 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Parkinson Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03336697's enrollment target sits among peer trials
48 164th of 297 higher than 134 of 297 other Parkinson Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Parkinson Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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