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NCT04452357 · ClinicalTrials.gov registry record · NA

Pulse-low-dose Rate (PLDR) Radiation in Pancreatic Cancer

A NA study of Pancreatic Cancer, sponsored by Fox Chase Cancer Center.

Active
Registry status
NA
Development phase
12
Enrollment target
1
Study location

NCT04452357: Active NA study of Pancreatic Cancer, sponsored by Fox Chase Cancer Center.

NCT04452357 is a NA study of Pancreatic Cancer that is active but no longer recruiting, run by Fox Chase Cancer Center. The registered enrollment target is 12 participants, below the 393-participant average among 278 other Pancreatic Cancer trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04452357, a NA study of Pancreatic Cancer, is active but no longer recruiting, sponsored by Fox Chase Cancer Center.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
12 participants
Enrollment target
1
Study location

Study Summary

Standard chemoradiation, followed by surgery are standard treatment plan for patients suffering from pancreatic adenocarcinoma. Due to damage to the surrounding healthy tissue caused by standard radiation, this study uses a new type of radiation plan- pulsed low-dose rate (PLDR) radiation , in combination with chemotherapeutic drug, gemcitabine, given weekly along with the radiation.

Primary Outcome

Number of participants with Grade 3 toxicity related to the treatment

Conditions Studied

Interventions

  • RADIATION PLDR

Study Locations (1)

Pennsylvania

  • Fox Chase Cancer Center - Philadelphia

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2020-01-13
Est. Completion 2025-12-01
Phase NA
Fox Chase Cancer Center

183 total trials

What the registry record for NCT04452357 still lists

NCT04452357 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 393-participant average among 278 other Pancreatic Cancer trials with a reported enrollment target (97% lower).

The record links to 1 condition, with Pancreatic Cancer appearing as the primary indexed condition, and to 1 intervention - of which PLDR is the first listed.

NCT04452357 reports a single indexed study location in Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT04452357 about?

NCT04452357 is a clinical study titled "Pulse-low-dose Rate (PLDR) Radiation in Pancreatic Cancer". Standard chemoradiation, followed by surgery are standard treatment plan for patients suffering from pancreatic adenocarcinoma. Due to damage to the surrounding healthy tissue caused by standard radiation, this study uses a new type of radiation plan- pulsed low-dose rate (PLDR) radiation , in combi...

What is the current status of trial NCT04452357?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 12 participants. The study started on 2020-01-13. Estimated completion is 2025-12-01.

What conditions does trial NCT04452357 study?

This clinical trial studies the following conditions: Pancreatic Cancer.

What interventions are being tested in trial NCT04452357?

The interventions under investigation include: PLDR (RADIATION).

Who is sponsoring clinical trial NCT04452357?

This trial is sponsored by Fox Chase Cancer Center, which has 183 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04452357 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Pancreatic Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04452357's enrollment target sits among peer trials

12 256th of 278 higher than 19 of 278 other Pancreatic Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Pancreatic Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04452357, the US trial registry maintained by the National Library of Medicine. NCT04452357 (small enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.