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ClinicalTrials.gov 101 recruiting now official registry

Pancreatic Cancer clinical trials

101 of 283 indexed Pancreatic Cancer trials are currently recruiting.

283 US clinical trials · 101 currently recruiting

Pancreatic Cancer is the subject of 283 registered US clinical trials on ClinicalTrials.gov, 101 of them currently open to new participants. 12 are in Phase 3-4 (later-stage) and 180 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 19 of these trials.

The research picture

Pancreatic Cancer has 283 registered US clinical trials, 101 of them open to new participants right now, about 36% of the total.

101
recruiting participants now
36%
of trials open to enrollment
12
in Phase 3–4 (later-stage)
19
top sponsor: Memorial Sloan Kettering Cancer Center
Phase 1114Phase 266Phase 310Phase 42

Active & Recent Trials

283 total, page 5 of 6

COMPLETED Phase 2 84 participants

Phase II Randomized Trial of mFOLFIRINOX +/- Ramucirumab in Advanced Pancreatic Cancer

Walid Shaib, MD

NCT02581215

COMPLETED Early Phase 1 75 participants

Preoperative Rehabilitation During Neoadjuvant Therapy for Pancreatic Cancer

M.D. Anderson Cancer Center

NCT02295956

COMPLETED Phase 2 75 participants

Study of Modified FOLFIRINOX in Advanced Pancreatic Cancer

Yale University

NCT01523457

COMPLETED Phase 1 73 participants

A Bioequivalence Study Between the Proposed and Current Talazoparib Capsule Formulation and Food Effect Study for the Proposed Talazoparib Capsule Formulation in Participants With Advanced Solid Tumors

Pfizer

NCT04672460

COMPLETED Phase 2 65 participants

Open-label Study of CS-1008 for Subjects With Untreated and Unresectable Pancreatic Cancer

Daiichi Sankyo

NCT00521404

COMPLETED Phase 1 65 participants

Immune Checkpoint Inhibition (Tremelimumab and/or MEDI4736) in Combination With Radiation Therapy in Patients With Unresectable Pancreatic Cancer

National Cancer Institute (NCI)

NCT02311361

COMPLETED Phase 2 60 participants

Vaccine Therapy Combined With Adjuvant Chemoradiotherapy in Treating Patients With Resected Stage I or Stage II Adenocarcinoma (Cancer) of the Pancreas

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT00084383

COMPLETED Phase 2 60 participants

Vaccine Therapy, Cyclophosphamide, and Cetuximab in Treating Patients With Metastatic or Locally Advanced Pancreatic Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT00305760

COMPLETED Phase 2 59 participants

Gemcitabine Plus Oxaliplatin in Treating Patients With Refractory Locally Advanced or Metastatic Pancreatic Cancer

Alliance for Clinical Trials in Oncology

NCT00004190

COMPLETED Phase 2 58 participants

Study With CY, Pembrolizumab, GVAX Pancreas Vaccine, and SBRT in Patients With Locally Advanced Pancreatic Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT02648282

COMPLETED Phase 2 52 participants

LY3214996 +/- HCQ in Pancreatic Cancer

Kimberly Perez, MD

NCT04386057

COMPLETED Phase 1 50 participants

Maytansinoid DM4-Conjugated Humanized Monoclonal Antibody huC242 in Treating Patients With Solid Tumors

ImmunoGen

NCT00352131

COMPLETED Phase 2 48 participants

Perioperative Therapy for Resectable and Borderline-Resectable Pancreatic Adenocarcinoma With Molecular Correlates

Academic Thoracic Oncology Medical Investigators Consortium

NCT02723331

COMPLETED Phase 2 48 participants

ChemoRT With Adjuvant Chemo in Pancreatic Cancer (TARCEVA)

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT00313560

COMPLETED Phase 1 48 participants

A Study of CDX-1307, in Patients With Incurable Breast, Colorectal, Pancreatic, Ovarian or Bladder Cancer (CDX 1307-01)

Celldex Therapeutics

NCT00709462

COMPLETED Phase 1 45 participants

Gemcitabine and Capecitabine to Treat Patients With Advanced Pancreatic and Biliary Cancers

University of California, San Francisco

NCT00626158

COMPLETED Phase 1 44 participants

LYT-200 Alone and in Combination With Chemotherapy or Tislelizumab in Patients With Locally Advanced or Metastatic Solid Tumors

PureTech

NCT04666688

COMPLETED Phase 2 43 participants

Paclitaxel in Treating Patients With Unresectable Locally Advanced or Metastatic Pancreatic Cancer

Theradex

NCT00111904

COMPLETED 40 participants

Clinical Registry of nCLE in Masses and Cystic Tumors of the Pancreas, Lymph Nodes, Submucosal Lesions of the GI Tract

Mauna Kea Technologies

NCT01770405

COMPLETED Phase 2 40 participants

R115777 in Treating Patients Who Have Metastatic Pancreatic Cancer

National Cancer Institute (NCI)

NCT00005843

COMPLETED Phase 2 40 participants

Cyclophosphamide Plus Vaccine Therapy in Treating Patients With Advanced Cancer

St. Vincent Medical Center - Los Angeles

NCT00002475

COMPLETED 40 participants

A Study to Collect Survival Data on Patients Previously Enrolled in Abraxane Pancreatic Cancer Study CA046.

Celgene

NCT02021500

COMPLETED Phase 2 40 participants

Efficacy and Safety Study of LE-DT to Treat Locally Advanced or Metastatic Pancreatic Cancer

INSYS Therapeutics

NCT01186731

COMPLETED Phase 2 39 participants

A Trial of Gemcitabine, Infusional 5-Fluorouracil and Cisplatin for Advanced Pancreatic and Biliary Cancers

University of Michigan Rogel Cancer Center

NCT01661114

COMPLETED Phase 2 37 participants

Sorafenib and Erlotinib in Treating Patients With Pancreatic Cancer That Cannot Be Removed by Surgery

Vanderbilt-Ingram Cancer Center

NCT00837876

COMPLETED Phase 1 36 participants

A Study of Romidepsin (Depsipeptide) in Combination With Gemcitabine in Patients With Pancreatic and Other Advanced Solid Tumors

Celgene

NCT00379639

COMPLETED Phase 2 36 participants

Bevacizumab and Erlotinib in Treating Patients With Metastatic Pancreatic Cancer That Did Not Respond to Previous Treatment With Gemcitabine

University of California, San Francisco

NCT00365144

COMPLETED Phase 2 34 participants

Preoperative Folfirinox, Radiation Therapy for Resectable Adenocarcinoma of the Pancreas

M.D. Anderson Cancer Center

NCT01560949

COMPLETED Phase 1 33 participants

Neoantigen Vaccines in Pancreatic Cancer in the Window Prior to Surgery

Washington University School of Medicine

NCT05111353

COMPLETED Phase 1 33 participants

Positron Emission Tomography Using [18F]-Labeled Substance P Antagonist Receptor Quantifier in Finding Disease in Patients With Pancreatic Cancer

National Institutes of Health Clinical Center (CC)

NCT00547612

COMPLETED Phase 2 32 participants

Gemcitabine, Bevacizumab and Erlotinib in Pancreatic Cancer

Massachusetts General Hospital

NCT00366457

COMPLETED Phase 2 32 participants

Tarceva and Capecitabine for Pancreatic Cancer

Dana-Farber Cancer Institute

NCT00125021

COMPLETED Phase 1 30 participants

Nab-Paclitaxel Plus Gemcitabine With Concurrent MR-Guided IMRT in Patients With Locally Advanced Pancreatic Cancer

Washington University School of Medicine

NCT02283372

COMPLETED Phase 2 30 participants

Combination Chemotherapy in Treating Patients With Stage III or Stage IV Pancreatic Cancer That Cannot Be Removed by Surgery

Barbara Ann Karmanos Cancer Institute

NCT00004003

COMPLETED Phase 1 30 participants

Administration as a Biological Adjuvant in Clinically-Staged, Resectable Pancreatic Adenocarcinoma

Edward Nelson

NCT00600002

COMPLETED 30 participants

Ablation of Unresectable Locally Advanced Pancreatic Cancer With Irreversible Electroporation (IRE) System

Holy Name Medical Center

NCT03614910

COMPLETED Phase 1 28 participants

Gemcitabine Hydrochloride, Oxaliplatin, and Erlotinib Hydrochloride in Treating Patients With Advanced Biliary Tract Cancer, Pancreatic Cancer, Duodenal Cancer, or Ampullary Cancer

Vanderbilt-Ingram Cancer Center

NCT00987766

COMPLETED Phase 2 28 participants

Gemcitabine and Celecoxib in Treating Patients With Metastatic Pancreatic Cancer

M.D. Anderson Cancer Center

NCT00068432

COMPLETED NA 28 participants

Trial Comparing EUS-guided Radiofrequency Ablation vs. EUS-guided Celiac Plexus Neurolysis

AdventHealth

NCT03152487

COMPLETED Phase 2 26 participants

Gemcitabine and Radiation Therapy in Treating Patients With Cancer of the Pancreas

Wake Forest University Health Sciences

NCT00010166

COMPLETED Phase 2 25 participants

BrUOG 295: Adjuvant FOLFOX-A For Resected Pancreatic Cancer: A Phase II Brown University Oncology Research Group Trial

Brown University

NCT02022033

COMPLETED Phase 2 25 participants

Calcitriol and Docetaxel in Treating Patients With Metastatic or Locally Advanced Pancreatic Cancer

OHSU Knight Cancer Institute

NCT00238199

COMPLETED Phase 1 25 participants

Vaccine Therapy in Treating Patients With Resected or Locally Advanced Unresectable Pancreatic Cancer

University of Pittsburgh

NCT00008099

COMPLETED Phase 3 24 participants

Endoscopic Biliary Co-axial Stent Placement Plus/Minus Use of Radiofrequency Ablation (RFA) for Clearance of Occluded Self Expandable Metal Stents (SEMS) in Patients With Distal Biliary Obstruction From Unresectable Biliary-pancreatic Malignancies

Memorial Sloan Kettering Cancer Center

NCT02340728

COMPLETED Phase 2 24 participants

Vaccine Therapy, Interleukin-2, and Sargramostim in Treating Patients With Advanced Tumors

Georgetown University

NCT00003125

COMPLETED NA 23 participants

Secretin-Stimulated Magnetic Resonance Cholangiopancreatography (S-MRCP) in Pancreatic Patients

Elizabeth Hecht

NCT01094561

COMPLETED Phase 1 23 participants

Gemcitabine/Capecitabine/ZD6474 in Advanced Solid Tumors

University of Colorado, Denver

NCT00551096

COMPLETED Phase 1 22 participants

Study of Irinotecan Administered as a Continuous Infusion and Radiation Therapy for Upper Gastrointestinal Cancers

University of Southern California

NCT00183846

COMPLETED Phase 2 20 participants

Abraxane Therapy in Patients With Pancreatic Cancer Who Failed First-Line Gemcitabine Therapy

University of Miami

NCT00691054

COMPLETED Early Phase 1 20 participants

Cancer Coaching and Remote Education for Self-Empowerment (CARES) Study

H. Lee Moffitt Cancer Center and Research Institute

NCT06323291

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Phase Distribution

PhaseTrial count
Phase 1 114
Phase 2 66
Phase 3 10
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Pancreatic Cancer Trial Landscape

283 indexed Pancreatic Cancer studies · 101 recruiting (36%).

Phase mix: 12 late (III/IV) vs 180 early (I/II).

Top sponsor: Memorial Sloan Kettering Cancer Center (19 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Pancreatic Cancer?

PlainTrial tracks 283 US clinical trials for Pancreatic Cancer, of which 101 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Pancreatic Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.