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NCT00002734 · ClinicalTrials.gov registry record · Phase 1

Radiolabeled Monoclonal Antibody, Paclitaxel, and Interferon Alfa in Treating Patients With Recurrent Ovarian Cancer

A Phase 1 study of Ovarian Cancer and Primary Peritoneal Cavity Cancer, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 1
Development phase
30
Enrollment target
1
Study location

NCT00002734 is a Phase 1 study of Ovarian Cancer and Primary Peritoneal Cavity Cancer that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 30 participants, below the 729-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00002734, a Phase 1 study of Ovarian Cancer and Primary Peritoneal Cavity Cancer, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 1
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

Phase I trial to study the effectiveness of radiolabeled monoclonal antibody, paclitaxel, and interferon alfa in treating patients who have ovarian cancer. Radiolabeled monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Interferon may interfere with the growth of cancer cells. Combining monoclonal antibody, chemotherapy, and interferon alfa may kill more tumor cells.

Interventions

  • DRUG paclitaxel
  • DRUG chemotherapy
  • DRUG topotecan hydrochloride
  • BIOLOGICAL recombinant interferon alfa
  • RADIATION lutetium Lu 177 monoclonal antibody CC49

Study Locations (1)

Alabama

  • University of Alabama Comprehensive Cancer Center - Birmingham

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 1996-03
Phase Phase 1

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT00002734

The ClinicalTrials.gov registry entry for NCT00002734 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 729-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (96% lower). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Ovarian Cancer appearing as the primary indexed condition, and to 5 interventions - of which paclitaxel is the first listed.

NCT00002734 reports 1 study location spanning 1 distinct geographic area - top geographies include Alabama.

Frequently Asked Questions

What is clinical trial NCT00002734 about?

NCT00002734 is a clinical study titled "Radiolabeled Monoclonal Antibody, Paclitaxel, and Interferon Alfa in Treating Patients With Recurrent Ovarian Cancer". Phase I trial to study the effectiveness of radiolabeled monoclonal antibody, paclitaxel, and interferon alfa in treating patients who have ovarian cancer. Radiolabeled monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming norma...

What is the current status of trial NCT00002734?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 1996-03.

What conditions does trial NCT00002734 study?

This clinical trial studies the following conditions: Ovarian Cancer, Primary Peritoneal Cavity Cancer.

What interventions are being tested in trial NCT00002734?

The interventions under investigation include: paclitaxel (DRUG), chemotherapy (DRUG), topotecan hydrochloride (DRUG), recombinant interferon alfa (BIOLOGICAL), lutetium Lu 177 monoclonal antibody CC49 (RADIATION).

Who is sponsoring clinical trial NCT00002734?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00002734 being conducted?

This trial has 1 study location across Alabama. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.