Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00002559 · ClinicalTrials.gov registry record · Phase 1

Combination Chemotherapy in Treating Patients With Germ Cell Tumors That Have Not Responded to Previous Cisplatin

A Phase 1 study of Ovarian Cancer and Testicular Germ Cell Tumor, sponsored by Memorial Sloan Kettering Cancer Center.

Completed
Registry status
Phase 1
Development phase
43
Enrollment target
1
Study location

NCT00002559: Completed Phase 1 study of Ovarian Cancer and Testicular Germ Cell Tumor, sponsored by Memorial Sloan Kettering Cancer Center.

NCT00002559 is a Phase 1 study of Ovarian Cancer and Testicular Germ Cell Tumor that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 43 participants, below the 729-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00002559, a Phase 1 study of Ovarian Cancer and Testicular Germ Cell Tumor, has completed, sponsored by Memorial Sloan Kettering Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
43 participants
Enrollment target
1
Study location

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase I/II trial to study the effectiveness of combination chemotherapy consisting of paclitaxel, cisplatin, and ifosfamide in treating patients who have ovarian or testicular germ cell tumors that are refractory to platinum-containing chemotherapy.

Interventions

  • DRUG cisplatin
  • DRUG paclitaxel
  • DRUG ifosfamide
  • BIOLOGICAL filgrastim

Study Locations (1)

New York

  • Memorial Sloan-Kettering Cancer Center - New York

Trial Details

FieldValue
Enrollment Target 43 participants
Start Date 1994-01
Est. Completion 2003-01
Phase Phase 1
Memorial Sloan Kettering Cancer Center

1,884 total trials

What the finished NCT00002559 record still lists

NCT00002559 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 43 participants, a relatively small participant target, below the 729-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (94% lower).

The record links to 2 conditions, with Ovarian Cancer appearing as the primary indexed condition, and to 4 interventions - of which cisplatin is the first listed.

NCT00002559 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT00002559 about?

NCT00002559 is a clinical study titled "Combination Chemotherapy in Treating Patients With Germ Cell Tumors That Have Not Responded to Previous Cisplatin". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase I/II trial to study the effectiveness of combination chemotherapy consisting of paclitaxel, cisplatin, and i...

What is the current status of trial NCT00002559?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 43 participants. The study started on 1994-01. Estimated completion is 2003-01.

What conditions does trial NCT00002559 study?

This clinical trial studies the following conditions: Ovarian Cancer, Testicular Germ Cell Tumor.

What interventions are being tested in trial NCT00002559?

The interventions under investigation include: cisplatin (DRUG), paclitaxel (DRUG), ifosfamide (DRUG), filgrastim (BIOLOGICAL).

Who is sponsoring clinical trial NCT00002559?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00002559 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Ovarian Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00002559's enrollment target sits among peer trials

43 222nd of 322 higher than 100 of 322 other Ovarian Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Ovarian Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03726359 · 43 participants · Phase 1

    Phase I Study of Fractionated Stereotactic Radiation Therapy

  • NCT03850418 · 43 participants · Phase 2

    Azacitidine and Chimerism in MDS or AML Patients After Allogeneic Stem Cell Transplant

  • NCT04144023 · 43 participants · Phase 1

    A Vaccine (H2NVAC) Before Surgery for the Treatment of HER2-Expressing Ductal Carcinoma In Situ

  • NCT04176718 · 43 participants · Phase 2

    Daratumumab, Carfilzomib, Pomalidomide, Dexamethasone In MM

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00002559, the US trial registry maintained by the National Library of Medicine. NCT00002559 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.