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NCT03056833 · ClinicalTrials.gov registry record · Phase 1

Ribociclib (Ribociclib (LEE-011)) With Platinum-based Chemotherapy in Recurrent Platinum Sensitive Ovarian Cancer

A Phase 1 study of Ovarian Cancer and Fallopian Tube Cancer, sponsored by Ronald Buckanovich.

Completed
Registry status
Phase 1
Development phase
35
Enrollment target
8
Study locations

NCT03056833 is a Phase 1 study of Ovarian Cancer and Fallopian Tube Cancer that has completed, run by Ronald Buckanovich. The registered enrollment target is 35 participants, below the 729-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (95% lower). The trial reports 8 study locations across 2 states.

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The verdict

NCT03056833, a Phase 1 study of Ovarian Cancer and Fallopian Tube Cancer, has completed, sponsored by Ronald Buckanovich.

COMPLETED
Registry status
Phase 1
Development phase
35 participants
Enrollment target
8
Study locations

Study Summary

Investigators hypothesize that concurrent ribociclib treatment and chemotherapy will enhance the response to platinum-based therapy and maintenance therapy will slow ovarian cancer tumor growth leading to prolongation in progression free survival.

Interventions

  • DRUG Carboplatin
  • DRUG Paclitaxel
  • DRUG ribociclib

Study Locations (8)

Pennsylvania

  • UPMC Hillman Cancer Center Upper St. Clair - Bethel Park
  • UPMC Hillman Cancer Center Arnold Palmer at Mountain View - Greensburg
  • UPMC Hillman Cancer Center Arnold Palmer Medical at Norwin - Irwin
  • UPMC Hillman Cancer Center Arnold Palmer at Mt Pleasant - Mount Pleasant
  • University of Pittsburgh Medical Center - Pittsburgh
  • UPMC Hillman Cancer Center Passavant (OHA) - Pittsburgh
  • UPMC Hillman Cancer Center Washington - Washington

Michigan

  • University of Michigan Comprehensive Cancer Center - Ann Arbor

Trial Details

FieldValue
Enrollment Target 35 participants
Start Date 2017-06-10
Est. Completion 2022-08-01
Phase Phase 1

Sponsor

Ronald Buckanovich

2 total trials

What the Registry Record Tells You About NCT03056833

The ClinicalTrials.gov registry entry for NCT03056833 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 35 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 729-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (95% lower). The listed sponsor is Ronald Buckanovich, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Ovarian Cancer appearing as the primary indexed condition, and to 3 interventions - of which Carboplatin is the first listed.

NCT03056833 reports 8 study locations spanning 2 distinct geographic areas - top geographies include Pennsylvania, Michigan.

Frequently Asked Questions

What is clinical trial NCT03056833 about?

NCT03056833 is a clinical study titled "Ribociclib (Ribociclib (LEE-011)) With Platinum-based Chemotherapy in Recurrent Platinum Sensitive Ovarian Cancer". Investigators hypothesize that concurrent ribociclib treatment and chemotherapy will enhance the response to platinum-based therapy and maintenance therapy will slow ovarian cancer tumor growth leading to prolongation in progression free survival.

What is the current status of trial NCT03056833?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 35 participants. The study started on 2017-06-10. Estimated completion is 2022-08-01.

What conditions does trial NCT03056833 study?

This clinical trial studies the following conditions: Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Carcinoma.

What interventions are being tested in trial NCT03056833?

The interventions under investigation include: Carboplatin (DRUG), Paclitaxel (DRUG), ribociclib (DRUG).

Who is sponsoring clinical trial NCT03056833?

This trial is sponsored by Ronald Buckanovich, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03056833 being conducted?

This trial has 8 study locations across Michigan, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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