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Effectiveness of MORAb-003 in Women With Ovarian Cancer Who Have Relapsed After Platinum-Based Chemotherapy
NCT00318370 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to determine if an investigational drug called MORAb-003 is useful by itself or when used with other approved cancer drugs in treating women with ovarian cancer. MORAb-003 is a monoclonal antibody directed against an antigen on most ovarian cancers.
Conditions Studied
Interventions
- DRUG Farletuzumab
- DRUG Chemo Plus Far
Study Locations (20)
Louisiana
- Hematology and Oncology Specialists, LLC — Covington
- Jayne Gurtler, M.D. — Metairie
- Hematology and Oncology Specialists, LLC — Metarie
New Jersey
- The Center for Cancer and Hematologic Disease — Cherry Hill
- The Cancer Institute of New Jersey — New Brunswick
- Cooper University Hospital — Voorhees Township
Texas
- Mary Crowley Medical Research Center — Dallas
- South Texas Oncology & Hematology — San Antonio
- Tyler Cancer Center — Tyler
Virginia
- Northern Virginia Pelvic Surgery Associates — Annandale
- Peninsula Cancer Center — Newport News
Other
- Krankenhaus Nordwest — Frankfurt
- Nationales Centrum fur Tumorerkrankungen — Heidelberg
California
- Sharp HealthCare — San Diego
Indiana
- St. Vincent Gynecologic Oncology — Indianapolis
Maryland
- Johns Hopkins University — Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 58 participants |
| Start Date | 2006-05 |
| Est. Completion | 2010-06 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00318370
The ClinicalTrials.gov registry entry for NCT00318370 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 58 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Morphotek, which has 6 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 3 conditions, with Ovarian Cancer appearing as the primary indexed condition, and to 2 interventions — of which Farletuzumab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00318370 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Louisiana, New Jersey, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00318370 about?
NCT00318370 is a clinical study titled "Effectiveness of MORAb-003 in Women With Ovarian Cancer Who Have Relapsed After Platinum-Based Chemotherapy". The purpose of this study is to determine if an investigational drug called MORAb-003 is useful by itself or when used with other approved cancer drugs in treating women with ovarian cancer. MORAb-003 is a monoclonal antibody directed against an antigen on most ovarian cancers.
What is the current status of trial NCT00318370?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 58 participants. The study started on 2006-05. Estimated completion is 2010-06.
What conditions does trial NCT00318370 study?
This clinical trial studies the following conditions: Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Neoplasms. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00318370?
The interventions under investigation include: Farletuzumab (DRUG), Chemo Plus Far (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00318370?
This trial is sponsored by Morphotek, which has 6 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00318370 being conducted?
This trial has 20 study locations across California, Indiana, Louisiana, Maryland, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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