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NCT00318370 · ClinicalTrials.gov registry record · Phase 2

Effectiveness of MORAb-003 in Women With Ovarian Cancer Who Have Relapsed After Platinum-Based Chemotherapy

A Phase 2 study of Ovarian Cancer and Fallopian Tube Cancer, sponsored by Morphotek.

Completed
Registry status
Phase 2
Development phase
58
Enrollment target
20
Study locations

NCT00318370 is a Phase 2 study of Ovarian Cancer and Fallopian Tube Cancer that has completed, run by Morphotek. The registered enrollment target is 58 participants, below the 729-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (92% lower). The trial reports 20 study locations across 12 states.

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The verdict

NCT00318370, a Phase 2 study of Ovarian Cancer and Fallopian Tube Cancer, has completed, sponsored by Morphotek.

COMPLETED
Registry status
Phase 2
Development phase
58 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to determine if an investigational drug called MORAb-003 is useful by itself or when used with other approved cancer drugs in treating women with ovarian cancer. MORAb-003 is a monoclonal antibody directed against an antigen on most ovarian cancers.

Interventions

  • DRUG Farletuzumab
  • DRUG Chemo Plus Far

Study Locations (20)

Louisiana

  • Hematology and Oncology Specialists, LLC - Covington
  • Jayne Gurtler, M.D. - Metairie
  • Hematology and Oncology Specialists, LLC - Metarie

New Jersey

  • The Center for Cancer and Hematologic Disease - Cherry Hill
  • The Cancer Institute of New Jersey - New Brunswick
  • Cooper University Hospital - Voorhees Township

Texas

  • Mary Crowley Medical Research Center - Dallas
  • South Texas Oncology & Hematology - San Antonio
  • Tyler Cancer Center - Tyler

Virginia

  • Northern Virginia Pelvic Surgery Associates - Annandale
  • Peninsula Cancer Center - Newport News

Other

  • Krankenhaus Nordwest - Frankfurt
  • Nationales Centrum fur Tumorerkrankungen - Heidelberg

California

  • Sharp HealthCare - San Diego

Indiana

  • St. Vincent Gynecologic Oncology - Indianapolis

Maryland

  • Johns Hopkins University - Baltimore

Trial Details

FieldValue
Enrollment Target 58 participants
Start Date 2006-05
Est. Completion 2010-06
Phase Phase 2

Sponsor

Morphotek

20 total trials

What the Registry Record Tells You About NCT00318370

The ClinicalTrials.gov registry entry for NCT00318370 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 58 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 729-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (92% lower). The listed sponsor is Morphotek, which has 20 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Ovarian Cancer appearing as the primary indexed condition, and to 2 interventions - of which Farletuzumab is the first listed.

NCT00318370 reports 20 study locations spanning 12 distinct geographic areas - top geographies include Louisiana, New Jersey, Texas.

Frequently Asked Questions

What is clinical trial NCT00318370 about?

NCT00318370 is a clinical study titled "Effectiveness of MORAb-003 in Women With Ovarian Cancer Who Have Relapsed After Platinum-Based Chemotherapy". The purpose of this study is to determine if an investigational drug called MORAb-003 is useful by itself or when used with other approved cancer drugs in treating women with ovarian cancer. MORAb-003 is a monoclonal antibody directed against an antigen on most ovarian cancers.

What is the current status of trial NCT00318370?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 58 participants. The study started on 2006-05. Estimated completion is 2010-06.

What conditions does trial NCT00318370 study?

This clinical trial studies the following conditions: Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Neoplasms.

What interventions are being tested in trial NCT00318370?

The interventions under investigation include: Farletuzumab (DRUG), Chemo Plus Far (DRUG).

Who is sponsoring clinical trial NCT00318370?

This trial is sponsored by Morphotek, which has 20 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00318370 being conducted?

This trial has 20 study locations across California, Indiana, Louisiana, Maryland, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.