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NCT00000373 · ClinicalTrials.gov registry record · Phase 4
Treatment of Obsessive-Compulsive Disorder
A Phase 4 study of Obsessive - Compulsive Disorder, sponsored by University of Florida.
- Completed
- Registry status
- Phase 4
- Development phase
- 74
- Enrollment target
- 2
- Study locations
NCT00000373: Completed Phase 4 study of Obsessive - Compulsive Disorder, sponsored by University of Florida.
NCT00000373 is a Phase 4 study of Obsessive - Compulsive Disorder that has completed, run by University of Florida. The registered enrollment target is 74 participants, below the 2,064-participant average among 84 other Obsessive - Compulsive Disorder trials with a reported enrollment target (96% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00000373, a Phase 4 study of Obsessive - Compulsive Disorder, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 74 participants
- Enrollment target
- 2
- Study locations
Study Summary
The purpose of this study is to find the best treatment for Tourette's Syndrome (TS)-spectrum obsessive-compulsive disorder (OCD), which includes symptoms of TS, e.g., repeated and involuntary body movements (tics). There are 2 parts to this study: In Part 1, patients are placed into 1 of 2 groups based on type of OCD, determined by medical history and family member interviews. In Part 2, patients are treated with fluvoxamine (FVX) for 8 weeks. If patients do not respond to FVX alone, either haloperidol or an inactive placebo will be added to the FVX regimen; patients will take this drug combination for 4 weeks. Patients will be monitored throughout the trial.
Conditions Studied
Interventions
- DRUG olanzapine + fluoxetine
- DRUG placebo + fluoxetine
Study Locations (2)
Florida
- Psychiatric Specialty Clinic, Shands Hospital at the University of Florida - Gainesville
- University of Florida Behavioral Health Mandarin Clinic - Jacksonville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 74 participants |
| Start Date | 1992-09 |
| Est. Completion | 2003-07 |
| Phase | Phase 4 |
What the finished NCT00000373 record still lists
NCT00000373 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 74 participants, a relatively small participant target, below the 2,064-participant average among 84 other Obsessive - Compulsive Disorder trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Obsessive - Compulsive Disorder appearing as the primary indexed condition, and to 2 interventions - of which olanzapine + fluoxetine is the first listed.
NCT00000373 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT00000373 about?
NCT00000373 is a clinical study titled "Treatment of Obsessive-Compulsive Disorder". The purpose of this study is to find the best treatment for Tourette's Syndrome (TS)-spectrum obsessive-compulsive disorder (OCD), which includes symptoms of TS, e.g., repeated and involuntary body movements (tics). There are 2 parts to this study: In Part 1, patients are placed into 1 of 2 groups ...
What is the current status of trial NCT00000373?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 74 participants. The study started on 1992-09. Estimated completion is 2003-07.
What conditions does trial NCT00000373 study?
This clinical trial studies the following conditions: Obsessive - Compulsive Disorder.
What interventions are being tested in trial NCT00000373?
The interventions under investigation include: olanzapine + fluoxetine (DRUG), placebo + fluoxetine (DRUG).
Who is sponsoring clinical trial NCT00000373?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00000373 being conducted?
This trial has 2 study locations across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obsessive - Compulsive Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00000373's enrollment target sits among peer trials
74 35th of 84 higher than 50 of 84 other Obsessive - Compulsive Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obsessive - Compulsive Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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