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NCT00074815 · ClinicalTrials.gov registry record · Phase 3
Treatment of Obsessive Compulsive Disorder in Children
A Phase 3 study of Obsessive - Compulsive Disorder, sponsored by Duke University.
- Completed
- Registry status
- Phase 3
- Development phase
- 124
- Enrollment target
- 3
- Study locations
NCT00074815: Completed Phase 3 study of Obsessive - Compulsive Disorder, sponsored by Duke University.
NCT00074815 is a Phase 3 study of Obsessive - Compulsive Disorder that has completed, run by Duke University. The registered enrollment target is 124 participants, below the 2,063-participant average among 84 other Obsessive - Compulsive Disorder trials with a reported enrollment target (94% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00074815, a Phase 3 study of Obsessive - Compulsive Disorder, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 124 participants
- Enrollment target
- 3
- Study locations
Study Summary
This study will determine whether cognitive behavioral therapy delivered by either psychologists or psychiatrists can improve the effectiveness of serotonin reuptake inhibitor treatment in children with obsessive compulsive disorder.
Primary Outcome
OCD symptom severity was measured using the CY-BOCS, an interviewer-rated instrument that assess obsessions and compulsions separately on time consumed, distress, interference, degree of resistance, and control; it yields separate severity scores for obsessions and for compulsions (0 - 20), and a composite symptom severity score (0 to 40). Consistent with signal detection analyses examining the optimal criterion for treatment response, a CY-BOCS reduction of 30% or more from baseline to week 12
Conditions Studied
Interventions
- DRUG Serotonin reuptake inhibitors management
- BEHAVIORAL Cognitive behavioral therapy by a psychologist
- BEHAVIORAL Instructional cognitive behavioral therapy by a psychiatrist
Study Locations (3)
North Carolina
- Duke Child and Family Study Center - Durham
Pennsylvania
- University of Pennsylvania, The Center for the Treatment and Study of Anxiety - Philadelphia
Rhode Island
- Rhode Island Hospital - Providence
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 124 participants |
| Start Date | 2003-09 |
| Est. Completion | 2009-11 |
| Phase | Phase 3 |
What the finished NCT00074815 record still lists
NCT00074815 is an interventional study that assigns participants to a tested intervention. The registered 124 participants enrollment target is mid-sized for trials with a published cap, below the 2,063-participant average among 84 other Obsessive - Compulsive Disorder trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Obsessive - Compulsive Disorder appearing as the primary indexed condition, and to 3 interventions - of which Serotonin reuptake inhibitors management is the first listed.
NCT00074815 reports a single indexed study location in North Carolina, Pennsylvania, Rhode Island.
Frequently Asked Questions
What is clinical trial NCT00074815 about?
NCT00074815 is a clinical study titled "Treatment of Obsessive Compulsive Disorder in Children". This study will determine whether cognitive behavioral therapy delivered by either psychologists or psychiatrists can improve the effectiveness of serotonin reuptake inhibitor treatment in children with obsessive compulsive disorder.
What is the current status of trial NCT00074815?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 124 participants. The study started on 2003-09. Estimated completion is 2009-11.
What conditions does trial NCT00074815 study?
This clinical trial studies the following conditions: Obsessive - Compulsive Disorder.
What interventions are being tested in trial NCT00074815?
The interventions under investigation include: Serotonin reuptake inhibitors management (DRUG), Cognitive behavioral therapy by a psychologist (BEHAVIORAL), Instructional cognitive behavioral therapy by a psychiatrist (BEHAVIORAL).
Who is sponsoring clinical trial NCT00074815?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00074815 being conducted?
This trial has 3 study locations across North Carolina, Pennsylvania, Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obsessive - Compulsive Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00074815's enrollment target sits among peer trials
124 25th of 84 higher than 60 of 84 other Obsessive - Compulsive Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obsessive - Compulsive Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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