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NCT04580043 · ClinicalTrials.gov registry record · NA
Theta Burst Stimulation Plus Habit Override Training for Compulsive Behaviors
A NA study of Obsessive - Compulsive Disorder and Compulsive Behavior, sponsored by Rebecca Price.
- Completed
- Registry status
- NA
- Development phase
- 203
- Enrollment target
- 1
- Study location
NCT04580043: Completed NA study of Obsessive - Compulsive Disorder and Compulsive Behavior, sponsored by Rebecca Price.
NCT04580043 is a NA study of Obsessive - Compulsive Disorder and Compulsive Behavior that has completed, run by Rebecca Price. The registered enrollment target is 203 participants, below the 2,062-participant average among 84 other Obsessive - Compulsive Disorder trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04580043, a NA study of Obsessive - Compulsive Disorder and Compulsive Behavior, has completed, sponsored by Rebecca Price.
- COMPLETED
- Registry status
- NA
- Development phase
- 203 participants
- Enrollment target
- 1
- Study location
Study Summary
This project seeks to identify causal neural mechanisms underlying unwanted, repetitive behaviors (compulsions). Using non-invasive brain stimulation coupled with practice in a computer task, we will modulate activity in a target brain region and measure effects on compulsive behaviors and related measures. This work could ultimately lead to the ability to treat compulsions more effectively by targeting the regions of the brain that can help or hinder attempts to overcome compulsions.
Primary Outcome
Mean Cerebral Blood Flow (CBF) in orbitofrontal cortex collected via functional Magnetic Resonance Imaging (fMRI)
Conditions Studied
Interventions
- DEVICE Transcranial Magnetic Stimulation
- BEHAVIORAL Sham Training
- DEVICE Sham Transcranial Magnetic Stimulation
- BEHAVIORAL Habit Override Practice
Study Locations (1)
Pennsylvania
- Western Psychiatric Institute and Clinic - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 203 participants |
| Start Date | 2020-12-28 |
| Est. Completion | 2025-12-15 |
| Phase | NA |
What the finished NCT04580043 record still lists
NCT04580043 is an interventional study that assigns participants to a tested intervention. The registered 203 participants enrollment target is mid-sized for trials with a published cap, below the 2,062-participant average among 84 other Obsessive - Compulsive Disorder trials with a reported enrollment target (90% lower).
The record links to 2 conditions, with Obsessive - Compulsive Disorder appearing as the primary indexed condition, and to 4 interventions - of which Transcranial Magnetic Stimulation is the first listed.
NCT04580043 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT04580043 about?
NCT04580043 is a clinical study titled "Theta Burst Stimulation Plus Habit Override Training for Compulsive Behaviors". This project seeks to identify causal neural mechanisms underlying unwanted, repetitive behaviors (compulsions). Using non-invasive brain stimulation coupled with practice in a computer task, we will modulate activity in a target brain region and measure effects on compulsive behaviors and related m...
What is the current status of trial NCT04580043?
This trial is currently completed. It is a NA study. The enrollment target is 203 participants. The study started on 2020-12-28. Estimated completion is 2025-12-15.
What conditions does trial NCT04580043 study?
This clinical trial studies the following conditions: Obsessive - Compulsive Disorder, Compulsive Behavior.
What interventions are being tested in trial NCT04580043?
The interventions under investigation include: Transcranial Magnetic Stimulation (DEVICE), Sham Training (BEHAVIORAL), Sham Transcranial Magnetic Stimulation (DEVICE), Habit Override Practice (BEHAVIORAL).
Who is sponsoring clinical trial NCT04580043?
This trial is sponsored by Rebecca Price, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04580043 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04580043's enrollment target sits among peer trials
203 17th of 84 higher than 68 of 84 other Obsessive - Compulsive Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obsessive - Compulsive Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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