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NCT01172873 · ClinicalTrials.gov registry record · NA

D-Cycloserine Augmentation to CBT With Exposure and Response Prevention in Adults and Adolescents With OCD

A NA study of Obsessive - Compulsive Disorder, sponsored by New York State Psychiatric Institute.

Completed
Registry status
NA
Development phase
16
Enrollment target
1
Study location

NCT01172873: Completed NA study of Obsessive - Compulsive Disorder, sponsored by New York State Psychiatric Institute.

NCT01172873 is a NA study of Obsessive - Compulsive Disorder that has completed, run by New York State Psychiatric Institute. The registered enrollment target is 16 participants, below the 2,064-participant average among 84 other Obsessive - Compulsive Disorder trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01172873, a NA study of Obsessive - Compulsive Disorder, has completed, sponsored by New York State Psychiatric Institute.

COMPLETED
Registry status
NA
Development phase
16 participants
Enrollment target
1
Study location

Study Summary

This is a single site, open-label, feasibility study of cognitive behavioral therapy with exposure and response prevention (CBT/ERP) adding the augmentation of D-cycloserine (DCS) for adolescents ages 12-17 with Obsessive Compulsive Disorder (OCD) who are partial or non-responders to first line treatments of CBT or pharmacotherapy.

Primary Outcome

The CYBOCS is a semi-structured measure of Obsessive Compulsive Disorder (OCD) severity with excellent inter-rater reliability, internal consistency, and test-retest reliability. It is validated in those starting at age 7 and used in studies up to age 20.The CYBOCS differs from the adult Yale-Brown Obsessive Compulsive Scale (YBOCS) only in its use of simpler language. CYBOCS scores range from 0-40, with higher scores representing greater severity of symptoms. The CYBOCS will be administered by

Interventions

  • DRUG D-cycloserine
  • BEHAVIORAL Exposure and Response Prevention (EX/RP)

Study Locations (1)

New York

  • New York State Psychiatric Institute/Columbia University - New York

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2008-09
Est. Completion 2010-12
Phase NA

What the finished NCT01172873 record still lists

NCT01172873 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 2,064-participant average among 84 other Obsessive - Compulsive Disorder trials with a reported enrollment target (99% lower).

The record links to 1 condition, with Obsessive - Compulsive Disorder appearing as the primary indexed condition, and to 2 interventions - of which D-cycloserine is the first listed.

NCT01172873 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT01172873 about?

NCT01172873 is a clinical study titled "D-Cycloserine Augmentation to CBT With Exposure and Response Prevention in Adults and Adolescents With OCD". This is a single site, open-label, feasibility study of cognitive behavioral therapy with exposure and response prevention (CBT/ERP) adding the augmentation of D-cycloserine (DCS) for adolescents ages 12-17 with Obsessive Compulsive Disorder (OCD) who are partial or non-responders to first line trea...

What is the current status of trial NCT01172873?

This trial is currently completed. It is a NA study. The enrollment target is 16 participants. The study started on 2008-09. Estimated completion is 2010-12.

What conditions does trial NCT01172873 study?

This clinical trial studies the following conditions: Obsessive - Compulsive Disorder.

What interventions are being tested in trial NCT01172873?

The interventions under investigation include: D-cycloserine (DRUG), Exposure and Response Prevention (EX/RP) (BEHAVIORAL).

Who is sponsoring clinical trial NCT01172873?

This trial is sponsored by New York State Psychiatric Institute, which has 364 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01172873 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Obsessive - Compulsive Disorder

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01172873's enrollment target sits among peer trials

16 72nd of 84 higher than 12 of 84 other Obsessive - Compulsive Disorder trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Obsessive - Compulsive Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01172873, the US trial registry maintained by the National Library of Medicine. NCT01172873 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.