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NCT03448185 · ClinicalTrials.gov registry record · NA
Improving Metabolic Health in Patients With Diastolic Dysfunction
A NA study of Obesity and Metabolic Syndrome, sponsored by University of Texas Southwestern Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT03448185: Completed NA study of Obesity and Metabolic Syndrome, sponsored by University of Texas Southwestern Medical Center.
NCT03448185 is a NA study of Obesity and Metabolic Syndrome that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 80 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03448185, a NA study of Obesity and Metabolic Syndrome, has completed, sponsored by University of Texas Southwestern Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to determine whether 1 year of supervised exercise training in obese individuals at high risk for developing HF, incorporating high intensity interval training (HIIT) two to three times per week in conjunction with daily oral administration of omega-3 poly-unsaturated fatty acids will lead to reduction in visceral adiposity, regression of myocardial triglyceride levels and improvements in cardiac diastolic and vascular function.
Primary Outcome
Myocardial triglyceride (lipid) content will be measured using cardiac nuclear magnetic resonance spectroscopy. We quantified the total myocardial triglyceride (TG) resonance from water-suppressed spectra. Myocardial TG content relative to water (%) as well as relative amounts of myocardial TG was calculated from the available data.
Conditions Studied
Interventions
- BEHAVIORAL Yoga
- DIETARY_SUPPLEMENT Omega-3 fish oil
- BEHAVIORAL High intensity exercise
- DIETARY_SUPPLEMENT olive oil capsules
Study Locations (1)
Texas
- The Institute for Exercise and Environmental Medicine - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2015-06-01 |
| Est. Completion | 2019-07-01 |
| Phase | NA |
What the finished NCT03448185 record still lists
NCT03448185 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (90% lower).
The record links to 3 conditions, with Obesity appearing as the primary indexed condition, and to 4 interventions - of which Yoga is the first listed.
NCT03448185 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT03448185 about?
NCT03448185 is a clinical study titled "Improving Metabolic Health in Patients With Diastolic Dysfunction". The purpose of this study is to determine whether 1 year of supervised exercise training in obese individuals at high risk for developing HF, incorporating high intensity interval training (HIIT) two to three times per week in conjunction with daily oral administration of omega-3 poly-unsaturated fa...
What is the current status of trial NCT03448185?
This trial is currently completed. It is a NA study. The enrollment target is 80 participants. The study started on 2015-06-01. Estimated completion is 2019-07-01.
What conditions does trial NCT03448185 study?
This clinical trial studies the following conditions: Obesity, Metabolic Syndrome, Heart Failure, Diastolic.
What interventions are being tested in trial NCT03448185?
The interventions under investigation include: Yoga (BEHAVIORAL), Omega-3 fish oil (DIETARY_SUPPLEMENT), High intensity exercise (BEHAVIORAL), olive oil capsules (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT03448185?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03448185 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03448185's enrollment target sits among peer trials
80 546th of 1053 higher than 498 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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