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2026 data Public-data reference. official source

Myocardial Infarction

Open-data reference.

66 US clinical trials · 16 currently recruiting

Active & Recent Trials

RECRUITING 15,000 participants

Vascular Events In Patients Undergoing Same-day Noncardiac Surgery (VALIANCE) Study

Centre hospitalier de l'Université de Montréal (CHUM)

NCT04973397

RECRUITING 4,000 participants

Identification of Genomic Predictors of Adverse Events After Cardiac Surgery

Brigham and Women's Hospital

NCT01258231

RECRUITING 1,500 participants

AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor

Peerbridge Health

NCT06699056

RECRUITING NA 1,000 participants

Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II

AliveCor

NCT06271577

RECRUITING 550 participants

Circulating Markers for Ischemic Heart Disease

UConn Health

NCT00762333

RECRUITING NA 546 participants

Reducing Blood Pressure in Patients With High Cardiovascular Risk

University of Southern California

NCT05937685

RECRUITING NA 516 participants

MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation

University of California, San Francis

NCT05933083

RECRUITING 500 participants

Integration of Telemedicine and Home-Based Cardiac Rehabilitation: Feasibility, Efficacy, and Adherence

ROM Technologies

NCT05972070

RECRUITING 350 participants

Heart Attack Research Program: Platelet Sub-Study (HARP)

NYU Langone Health

NCT03022552

RECRUITING Phase 2 320 participants

Improving Cardiac Rehabilitation Exercise Using Target Heart Rate Trial

Baystate Medical Center

NCT05925634

RECRUITING 300 participants

Study of Circulating Monocytes in Patients With Ischemic Vascular Disease

UConn Health

NCT04321512

RECRUITING NA 200 participants

Women's Heart Attack Research Program: Stress Ancillary Study

NYU Langone Health

NCT02914483

RECRUITING Early Phase 1 160 participants

Diffusion MRI in Heart Failure

Massachusetts General Hospital

NCT02973633

RECRUITING NA 120 participants

Influence of Pulse Electromagnetic Field Therapy on Myocardial Ischemia

Mayo Clinic

NCT05111288

RECRUITING NA 100 participants

Examination of the Impact of CalmiGo's Stress Management Device on Vascular Heath and Cardiovascular Disease Risk.

Mayo Clinic

NCT04521699

RECRUITING NA 24 participants

Cardiac Radioablation for VT

Corewell Health East

NCT06593418

ACTIVE NOT RECRUITING 15,000 participants

Genomic Investigation of Cardiovascular Diseases

Scripps Translational Science Institute

NCT00722748

ACTIVE NOT RECRUITING Phase 4 6,019 participants

EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction

Amgen

NCT05284747

ACTIVE NOT RECRUITING 5,050 participants

Cangrelor in Acute Myocardial Infarction: Effectiveness and Outcomes Registry

Chiesi USA

NCT04076813

ACTIVE NOT RECRUITING 1,599 participants

Ventricular Remodeling and Heart Failure After Myocardial Infarction: A Community Study

Mayo Clinic

NCT02047396

ACTIVE NOT RECRUITING 450 participants

Heart Attack Research Program- Imaging Study

NYU Langone Health

NCT02905357

ACTIVE NOT RECRUITING 62 participants

Acute Kidney Injury Genomics and Biomarkers in TAVR Study

University of Texas Southwestern Medical Center

NCT02791880

ACTIVE NOT RECRUITING NA 15 participants

Research on Infarction With Open Arteries Using OCT and CMR

NYU Langone Health

NCT02270359

ACTIVE NOT RECRUITING Phase 1 6 participants

Neuroinflammation After Myocardial Infarction - Imaging Substudy

University of Alabama at Birmingham

NCT03968445

COMPLETED 173,464 participants

Type 2 Diabetes With Antiplatelet Drugs

Tabula Rasa HealthCare

NCT05053828

COMPLETED Phase 3 15,526 participants

An Efficacy and Safety Study for Rivaroxaban in Patients With Acute Coronary Syndrome

Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

NCT00809965

COMPLETED NA 10,800 participants

Testing a Community Intervention to Increase Aspirin Use

University of Minnesota

NCT02607917

COMPLETED Phase 3 8,000 participants

SYNERGY: Open Study of Enoxaparin Versus Unfractionated Heparin in Patients With Acute Coronary Syndromes

Sanofi

NCT00043784

COMPLETED 7,057 participants

The PACE-MI Registry Study - Outcomes of Beta-blocker Therapy After Myocardial Infarction (OBTAIN)

Northwestern University

NCT00430612

COMPLETED Phase 3 7,001 participants

Home Use of Automatic External Defibrillators to Treat Sudden Cardiac Arrest

National Heart, Lung, and Blood Institute (NHLBI)

NCT00047411

COMPLETED 6,000 participants

ECG Methods for the Prompt Identification of Coronary Events

University of Pittsburgh

NCT04237688

COMPLETED Phase 4 5,388 participants

INfluenza Vaccine to Effectively Stop Cardio Thoracic Events and Decompensated Heart Failure

Brigham and Women's Hospital

NCT02787044

COMPLETED Phase 3 2,201 participants

Occluded Artery Trial (OAT)

NYU Langone Health

NCT00004562

COMPLETED 2,067 participants

An Observational Study of Cholesterol in Coronary Arteries

Infraredx

NCT00831116

COMPLETED 940 participants

Safety of Nitroglycerin for Field Treatment of STEMI

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

NCT02407002

COMPLETED Phase 3 911 participants

IMMEDIATE Trial - Out of Hospital Administration of Glucose, Insulin and Potassium.

Tufts Medical Center

NCT00091507

COMPLETED 715 participants

Heart Rate Variability and Sudden Cardiac Death

Columbia University

NCT00005235

COMPLETED Phase 3 700 participants

Efficacy of Implantable Defibrillator Therapy After a Myocardial Infarction

University of Calgary

NCT00673842

COMPLETED Phase 4 634 participants

A Trial Evaluating Vitamin D Normalization on Major Adverse Cardiovascular-Related Events Among Myocardial Infarction Patients

Intermountain Health Care

NCT02996721

COMPLETED NA 431 participants

Disrupt CAD III With the Shockwave Coronary IVL System

Shockwave Medical

NCT03595176

COMPLETED Phase 2 414 participants

MCC-135 as Adjunct Therapy to Primary Percutaneous Coronary Intervention in ST-Segment Elevation Acute Myocardial Infarction Patients

Tanabe Pharma Corporation

NCT00078013

COMPLETED Phase 4 390 participants

Pre-hospital Administration of Thrombolytic Therapy With Urgent Culprit Artery Revascularization

The University of Texas Health Science Center, Houston

NCT00178620

COMPLETED 368 participants

Rule Out Myocardial Infarction by Computer Assisted Tomography

Massachusetts General Hospital

NCT00990262

COMPLETED Phase 2 360 participants

MRI Evaluation of Chest Pain

National Heart, Lung, and Blood Institute (NHLBI)

NCT00001961

COMPLETED Phase 3 358 participants

Effect of High Dose Fish Oil Supplementation After Recent Heart Attack Using Magnetic Resonance Imaging

Brigham and Women's Hospital

NCT00729430

COMPLETED 324 participants

Plaque Inflammation and Dysfunctional HDL in AIM-HIGH

University of Washington

NCT00880178

COMPLETED Phase 2 305 participants

At-Home Automated External Defibrillator (AED) Training Study

Public Health - Seattle and King County

NCT00219674

COMPLETED 250 participants

Diagnostic Utility of Contrast Echocardiography for Detection of LV Thrombi Post ST Elevation Myocardial Infarction

Weill Medical College of Cornell University

NCT00539045

COMPLETED Phase 4 248 participants

Bupropion for Hospitalized Smokers With Acute Cardiovascular Disease

Massachusetts General Hospital

NCT00181818

COMPLETED 190 participants

The Relationship Between the Response to Mental Stress and Vascular Endothelial Function

Mayo Clinic

NCT00975559

COMPLETED NA 145 participants

Shockwave C2+ 2Hz Coronary IVL Catheter in Calcified Coronary Arteries (Disrupt CAD DUO)

Shockwave Medical

NCT05966662

COMPLETED 130 participants

Identify Clinical Conditions That Increase Circulating DNA Levels

University of Florida

NCT01815996

COMPLETED 120 participants

Comparison of Asymptomatic Carotid Atherosclerosis Between Frequent and Infrequent Blood Donors

National Institutes of Health Clinical Center (CC)

NCT00001589

COMPLETED 117 participants

Genetic Variation in Platelet Aggregation

Vanderbilt University

NCT01576536

COMPLETED 110 participants

Heart Function and Exercise Capacity in Patients With Hypertrophic Cardiomyopathy

National Heart, Lung, and Blood Institute (NHLBI)

NCT00354328

COMPLETED Phase 3 110 participants

Myocardial Ischemia and Transfusion Pilot

Rutgers, The State University of New Jersey

NCT01167582

COMPLETED 101 participants

Magnetocardiography Using a Novel Analysis System (Cardioflux) in the Evaluation of Emergency Department Observation Unit Chest Pain Patients

Genetesis

NCT03255772

COMPLETED NA 65 participants

Differences in Epicardial Plaque and Microvascular Function in Women With an Acute Myocardial Infarction

Mayo Clinic

NCT00587002

COMPLETED Phase 1 60 participants

Safety Study of Adult Mesenchymal Stem Cells (MSC) to Treat Acute Myocardial Infarction

Mesoblast

NCT00114452

COMPLETED NA 55 participants

Mechanisms of Action of Acetaminophen

University of Pennsylvania

NCT00646906

COMPLETED NA 48 participants

Exercise Prescription in Cardiac Rehabilitation

Baystate Medical Center

NCT03925493

COMPLETED NA 47 participants

Mindfulness & Stress Management Study for Cardiac Patients

University of Minnesota

NCT02722213

COMPLETED 40 participants

Platelet Sub-study of the TWILIGHT Trial

Juan Badimon

NCT04001374

COMPLETED NA 39 participants

Clinical Evaluation of Cardiac Output Estimation Based on Pulse Wave Transit Time

University of California, San Francis

NCT01877941

COMPLETED NA 14 participants

HeartHome: A Nurse-Driven, Home-Based Cardiac Rehabilitation Program

University of North Carolina, Chapel Hill

NCT04131816

COMPLETED Phase 3

Vitamin Therapy for Prevention of Stroke

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00004734

Phase Distribution

PhaseTrial count
Early Phase 1 3
Phase 2 4
Phase 3 9
Phase 4 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Myocardial Infarction Trial Landscape

ClinicalTrials.gov lists 66 US studies indexed under Myocardial Infarction, and 16 of those are currently open to recruitment — roughly 24% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Myocardial Infarction shows 14 late-stage studies (Phase 3 and Phase 4 combined) alongside 7 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Myocardial Infarction is led by NYU Langone Health with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 66 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Myocardial Infarction?

PlainTrial tracks 66 US clinical trials for Myocardial Infarction, of which 16 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Myocardial Infarction?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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