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ClinicalTrials.gov 19 recruiting now full pipeline

Prostatic Neoplasms: full-pipeline trial registry

19 of 66 indexed Prostatic Neoplasms trials are currently recruiting.

Corpus placement: #211 of 28,707 conditions by registered trial count.

66 US clinical trials · 19 currently recruiting · #211 of 28,707 conditions by registered trial count

Prostatic Neoplasms: 66 US clinical trials tracked, 19 recruiting.

Prostatic Neoplasms is the subject of 66 registered US clinical trials on ClinicalTrials.gov, 19 of them currently open to new participants. 22 are in Phase 3-4 (later-stage) and 32 in Phase 1-2 (earlier-stage). The most active sponsor is Janssen Research & Development, running 8 of these trials.

Enrollment posture brief

Registry condition prostatic-neoplasms

OPEN 19 | RECR 29% | LATE 22 | EARLY 32 | RANK #211 | SPON 8

Nearest open-share peer: Cystic Fibrosis (29% recruiting · 170 trials)

Amputation57.6%Health Behavior33.3%Prostatic Neoplasms (this)29%Myocardial Infarction24.2%Alcoholism16.4%
Open-enrollment share among volume-matched conditions near Prostatic Neoplasms

Prostatic Neoplasms lists 19 open slots (29% of 66 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Prostatic Neoplasms on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Prostatic Neoplasms is recruiting below its size-band peers.

    19 of 66 indexed trials (28.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Prostatic Neoplasms trials is spread across many organizations.

    Janssen Research & Development accounts for 8 of 66 trials (12.1%). 39 distinct sponsors appear on at least one study for this condition label.

  3. Typical Prostatic Neoplasms enrolment sits around 144 participants.

    Median target enrolment is 144 among the 66 trials that report a genuine target (sentinel values excluded). 25 of those (37.9%) plan for fewer than 100 participants.

  4. Prostatic Neoplasms research is mostly interventional.

    57 interventional and 9 observational studies make up this index (86.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 118Phase 214Phase 321Phase 41

Open and recent trials

66 total, page 1 of 2

RECRUITING 3,000 participants

Prostate Active Surveillance Study

University of Washington

NCT00756665

RECRUITING Phase 3 1,440 participants

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

Merck Sharp & Dohme

NCT06925737

RECRUITING 1,400 participants

A Study to Learn About Real-world Utilization and Outcomes of Darolutamide and Other Androgen Receptor Pathway Inhibitors (ARPIs) for Newly Diagnosed Metastatic Hormone-sensitive Prostate Cancer (de Novo mHSPC) in US Urology Clinics

Bayer

NCT07406282

RECRUITING Phase 3 1,314 participants

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

Merck Sharp & Dohme

NCT06136650

RECRUITING 1,000 participants

Collection of Blood From Patients With Prostate Cancer

National Cancer Institute (NCI)

NCT00923221

RECRUITING 500 participants

Men at High Genetic Risk for Prostate Cancer

National Cancer Institute (NCI)

NCT03805919

RECRUITING Phase 3 383 participants

Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

Clarity Pharmaceuticals

NCT06056830

RECRUITING 300 participants

Imaging Studies to Check the Local Response of Prostate Cancer to Radiation Therapy

National Cancer Institute (NCI)

NCT01834001

RECRUITING Phase 1 252 participants

Open-Label Study of Pocenbrodib Alone and in Combination With Abiraterone Acetate, Olaparib, or 177Lu-PSMA-617

Pathos AI

NCT06785636

RECRUITING Phase 1 160 participants

A Study of DM002 in Patients With Advanced Solid Tumors

Xadcera Biopharmaceutical (Suzhou) Co.

NCT06751329

RECRUITING Phase 1 140 participants

A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer

Janssen Research & Development

NCT07082920

RECRUITING Phase 2 120 participants

Diagnostic Utility of rhPSMA-7.3 (18F) PET/CT in Men With Prostate Cancer on Active Surveillance

Icahn School of Medicine at Mount Sinai

NCT07285057

RECRUITING Phase 2 110 participants

RecoverPC: Relugolix vs GnRH Agonist in Quality of Life

Dana-Farber Cancer Institute

NCT05765500

RECRUITING Phase 1 82 participants

Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection

Blue Earth Therapeutics

NCT05413850

RECRUITING Phase 2 42 participants

Focal Therapy With Stereotactic Body Radiation Therapy (SBRT) for Patients With a Single Prostate Tumor

National Cancer Institute (NCI)

NCT05616650

RECRUITING Phase 1 40 participants

A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer

Janssen Research & Development

NCT07319871

RECRUITING Phase 1 25 participants

HSV-tk + Valacyclovir Therapy in Combination With Brachytherapy for Recurrent Prostate Cancer

The Methodist Hospital Research Institute

NCT01913106

RECRUITING NA 24 participants

Men With Prostate Cancer: Optimizing Wellness by Enhanced Relief From Hot Flashes With Acupuncture

Inova Health Care Services

NCT07335224

RECRUITING Phase 4 15 participants

18F-Fluciclovine PET/CT Impact on Predicting Clinical Outcome of 177Lu-PSMA-617 Therapy in Patients With Prostate Cancer

VA Greater Los Angeles Healthcare System

NCT06706921

ACTIVE NOT RECRUITING Phase 3 2,517 participants

A Study of Apalutamide in Participants With High-Risk, Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy

Janssen Research & Development

NCT03767244

ACTIVE NOT RECRUITING Phase 3 1,503 participants

An Efficacy and Safety Study of JNJ-56021927 (Apalutamide) in High-risk Prostate Cancer Subjects Receiving Primary Radiation Therapy: ATLAS

Aragon Pharmaceuticals

NCT02531516

ACTIVE NOT RECRUITING Phase 3 1,244 participants

Study of Pembrolizumab (MK-3475) Plus Enzalutamide Versus Placebo Plus Enzalutamide in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-641/KEYNOTE-641)

Merck Sharp & Dohme

NCT03834493

ACTIVE NOT RECRUITING Phase 3 1,207 participants

A Study of Apalutamide (ARN-509) in Men With Non-Metastatic Castration-Resistant Prostate Cancer

Aragon Pharmaceuticals

NCT01946204

ACTIVE NOT RECRUITING Phase 3 1,145 participants

An International Prospective Open-label, Randomized, Phase III Study Comparing 177Lu-PSMA-617 in Combination With Standard of Care (SoC), Versus SoC Alone, in Adult Male Patients With Metastatic Hormone Sensitive Prostate Cancer (mHSPC)

Novartis Pharmaceuticals

NCT04720157

ACTIVE NOT RECRUITING Phase 3 1,125 participants

Enzalutamide in First Line Androgen Deprivation Therapy for Metastatic Prostate Cancer

University of Sydney

NCT02446405

ACTIVE NOT RECRUITING 992 participants

Ascertainment of Peripheral Blood or Saliva Samples for Genetic Epidemiology Studies of Familial Cancers

Memorial Sloan Kettering Cancer Center

NCT00579163

ACTIVE NOT RECRUITING Phase 3 982 participants

An Efficacy and Safety Study of Apalutamide (JNJ-56021927) in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone in Participants With Chemotherapy-naive Metastatic Castration-resistant Prostate Cancer (mCRPC)

Aragon Pharmaceuticals

NCT02257736

ACTIVE NOT RECRUITING Phase 3 925 participants

A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer)

Eli Lilly and Company

NCT05288166

ACTIVE NOT RECRUITING Phase 3 802 participants

Enzalutamide in Androgen Deprivation Therapy With Radiation Therapy for High Risk, Clinically Localised, Prostate Cancer

University of Sydney

NCT02446444

ACTIVE NOT RECRUITING Phase 3 693 participants

A Study of Adding Apalutamide to Radiotherapy and LHRH Agonist in High-Risk Patients With Hormone-Sensitive Prostate Cancer

Janssen Pharmaceutica N.V., Belgium

NCT04557059

ACTIVE NOT RECRUITING Phase 3 469 participants

177Lu-PSMA-617 vs. Androgen Receptor-Directed Therapy in the Treatment of Progressive Metastatic Castrate Resistant Prostate Cancer

Novartis Pharmaceuticals

NCT04689828

ACTIVE NOT RECRUITING Phase 1 216 participants

A Study of JNJ-78278343, a T-Cell-Redirecting Agent Targeting Human Kallikrein 2 (KLK2), for Advanced Prostate Cancer

Janssen Research & Development

NCT04898634

ACTIVE NOT RECRUITING Phase 1 144 participants

A Study of JNJ-69086420, an Actinium-225-Labeled Antibody Targeting Human Kallikrein-2 (hK2) for Advanced Prostate Cancer

Janssen Research & Development

NCT04644770

ACTIVE NOT RECRUITING Phase 1 136 participants

A Study of Comparative Formulations of Niraparib and Abiraterone Acetate (AA) in Men With Prostate Cancer

Janssen Research & Development

NCT04577833

ACTIVE NOT RECRUITING Phase 2 129 participants

18F-DCFPyL Positron Emission Tomography (PET)/Computed Tomography (CT) in Men With Prostate Cancer

Columbia University

NCT03824275

ACTIVE NOT RECRUITING 118 participants

Evaluation of Atherosclerotic Plaques in Abdominal CT Studies

National Institutes of Health Clinical Center (CC)

NCT04652973

ACTIVE NOT RECRUITING Phase 2 109 participants

A Study Evaluating the Safety, Pharmacokinetics, and Clinical Effects of Intravenously Administered PT-112 Injection in Subjects With Advanced Solid Tumors and Subsequent Dose Expansion Cohorts

Promontory Therapeutics

NCT02266745

ACTIVE NOT RECRUITING Phase 2 96 participants

18F-DCFPyL PSMA- Versus 18F-NaF-PET Imaging for Detection of Metastatic Prostate Cancer

National Cancer Institute (NCI)

NCT03173924

ACTIVE NOT RECRUITING NA 68 participants

Exercise for Tumor Suppressive Impact in Black Men With Prostate Cancer on Active Surveillance: The REMOVE Trial

Dana-Farber Cancer Institute

NCT05918263

ACTIVE NOT RECRUITING Phase 1 57 participants

A Study of JNJ-56021927 (ARN-509) and Abiraterone Acetate in Participants With Metastatic Castration-Resistant Prostate Cancer

Aragon Pharmaceuticals

NCT02123758

ACTIVE NOT RECRUITING Phase 1 15 participants

A Study of JNJ-75229414 for Metastatic Castration-resistant Prostate Cancer Participants

Janssen Research & Development

NCT05022849

COMPLETED Phase 3 1,224 participants

Aflibercept in Combination With Docetaxel in Metastatic Androgen Independent Prostate Cancer

Sanofi

NCT00519285

COMPLETED Phase 3 1,195 participants

Abiraterone Acetate in Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy

Cougar Biotechnology

NCT00638690

COMPLETED Phase 3 1,030 participants

Study of Pembrolizumab (MK-3475) Plus Docetaxel Versus Placebo Plus Docetaxel in Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-921/KEYNOTE-921)

Merck Sharp & Dohme

NCT03834506

COMPLETED Phase 3 1,028 participants

Study of Cabozantinib (XL184) Versus Prednisone in Men With Metastatic Castration-resistant Prostate Cancer Previously Treated With Docetaxel and Abiraterone or MDV3100

Exelixis

NCT01605227

COMPLETED Phase 3 806 participants

Radium-223 Dichloride and Abiraterone Acetate Compared to Placebo and Abiraterone Acetate for Men With Cancer of the Prostate When Medical or Surgical Castration Does Not Work and When the Cancer Has Spread to the Bone, Has Not Been Treated With Chemotherapy and is Causing no or Only Mild Symptoms

Bayer

NCT02043678

COMPLETED Phase 3 793 participants

Study of Pembrolizumab (MK-3475) Plus Olaparib Versus Abiraterone Acetate or Enzalutamide in Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-7339-010/KEYLYNK-010)

Merck Sharp & Dohme

NCT03834519

COMPLETED Phase 3 755 participants

XRP6258 Plus Prednisone Compared to Mitoxantrone Plus Prednisone in Hormone Refractory Metastatic Prostate Cancer

Sanofi

NCT00417079

COMPLETED 714 participants

Retrospective Observational Study Investigating Fluciclovine (18F) (FACBC)

Blue Earth Diagnostics

NCT02443571

COMPLETED NA 307 participants

CyberKnife Radiosurgery For Low & Intermediate Risk Prostate Cancer: Emulating HDR Brachytherapy Dosimetry

Accuray Incorporated

NCT00643617

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Phase Distribution

PhaseTrial count
Phase 1 18
Phase 2 14
Phase 3 21
Phase 4 1

Named interventions

Most-linked intervention names on Prostatic Neoplasms records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Prednisone Drug
9 trials
Apalutamide Drug
7 trials
Abiraterone acetate Drug
6 trials
Enzalutamide Drug
6 trials
Placebo Drug
6 trials
JNJ-78278343 Drug
3 trials
Abiraterone Acetate Drug
3 trials
Docetaxel Drug
3 trials

US sites by state

Facility locations filed on Prostatic Neoplasms trials. A trial with sites in several states counts in each.

California 31 trials
Florida 23 trials
New York 19 trials
Colorado 19 trials
Arizona 15 trials
Georgia 14 trials
Texas 13 trials
Massachusetts 13 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Prostatic Neoplasms page

66 registered trials, 19 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Prostatic Neoplasms condition card totals 66 registered trials; most-linked intervention Prednisone; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.