Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Mental Disorder: early-phase trial registry
9 of 22 indexed Mental Disorder trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #756 of 28,707 conditions by registered trial count.
22 US clinical trials · 9 currently recruiting · #756 of 28,707 conditions by registered trial count
Mental Disorder: 22 US clinical trials tracked, 9 recruiting.
Mental Disorder is the subject of 22 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Otsuka Pharmaceutical Development & Commercialization, running 3 of these trials.
Enrollment posture brief
Registry condition mental-disorder
OPEN 9 | RECR 41% | LATE 2 | EARLY 5 | RANK #756 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Brain Injuries, Traumatic (41% recruiting · 22 trials)
Mental Disorder lists 9 open slots (41% of 22 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Mental Disorder on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Mental Disorder recruits in line with its size-band peers.
9 of 22 indexed trials (40.9%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Mental Disorder trials is spread across many organizations.
Otsuka Pharmaceutical Development & Commercialization accounts for 3 of 22 trials (13.6%). 16 distinct sponsors appear on at least one study for this condition label.
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Typical Mental Disorder enrolment sits around 150 participants.
Median target enrolment is 150 among the 22 trials that report a genuine target (sentinel values excluded). 9 of those (40.9%) plan for fewer than 100 participants.
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Mental Disorder research is mostly interventional.
18 interventional and 4 observational studies make up this index (81.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
22 total, page 1 of 1
GLP-1R Agonist Treatment for Opioid Use Disorder
Milton S. Hershey Medical Center
NCT06548490
Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness
Brigham and Women's Hospital
NCT06376734
Transdiagnostic Behavior Therapy Vs TAU for Adjustment Disorder Following Traumatic Event Exposure
The University of Texas Health Science Center, Houston
NCT06433271
Enhancing Immune Health Randomized Controlled Trial
University of Illinois at Chicago
NCT05639881
Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use
Massachusetts General Hospital
NCT06878859
Healthy ReStart Intervention to Improve Health and Functioning
University of Illinois at Chicago
NCT05544344
Brain Stimulation to the Hippocampus in Schizophrenia
Stanford University
NCT07010614
Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside
Mclean Hospital
NCT05245903
ACT for HIV-Positive Men
University of Alabama at Birmingham
NCT06625437
FCT Study: Reducing the Need for Out-of-Home Placements
Duke University
NCT03641664
Individualized Functional Connectivity Targeting in aiTBS for Depression
Brigham and Women's Hospital
NCT05680727
Psilocybin for the Treatment of Veterans With Post-Traumatic Stress Disorder
Ohio State University
NCT05554094
Testing a Transdiagnostic TMS Treatment Target
Brigham and Women's Hospital
NCT06282146
Mapping Personality Traits to Genes
National Institute of Mental Health (NIMH)
NCT00001414
Systems Aligning for Equity (SAFE) Spaces
New York University
NCT05658068
Safety Follow-up Study for Subjects With Agitation Associated With Dementia of the Alzheimer's Type Who Previously Participated in a Double-blind Trial of Brexpiprazole or Placebo
Otsuka Pharmaceutical Development & Commercialization
NCT02192554
A Phase 3, 12-week, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy, Safety, and Tolerability of 2 Fixed Doses of Brexpiprazole in the Treatment of Alzheimer's Agitation
Otsuka Pharmaceutical Development & Commercialization
NCT01862640
Safety and Tolerability Study of Flexible Dosing of Brexpiprazole in the Treatment of Subjects With Agitation Associated With Dementia of the Alzheimer's Type
Otsuka Pharmaceutical Development & Commercialization
NCT01922258
Peer Navigators to Address Obesity-Related Concerns for African Americans With Serious Mental Illness
Illinois Institute of Technology
NCT03382782
Neuropsychiatric Effects of Interferon-Alpha and Ribavirin
National Institute of Mental Health (NIMH)
NCT00001547
HIV/STI Prevention Among Black Adolescents With Mental Illnesses (Project GOLD)
University of Pennsylvania
NCT03348813
Family Promoting Positive Emotions Pilot Study
Vanderbilt University
NCT05223842
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 4 |
| Phase 3 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Mental Disorder records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Mental Disorder trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Mental Disorder page
22 registered trials, 9 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 9 Mental Disorder trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Otsuka Pharmaceutical Development & Commercialization sponsors the most Mental Disorder trials on record, review their full trial history before evaluating a specific study. See Otsuka Pharmaceutical Development & Commercialization's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Mental Disorder condition card totals 22 registered trials; most-linked intervention Brexpiprazole, OPC-34712; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.