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2026 data Public-data reference. official source

Mental Disorder

Open-data reference.

22 US clinical trials · 9 currently recruiting

Active & Recent Trials

RECRUITING Phase 2 200 participants

GLP-1R Agonist Treatment for Opioid Use Disorder

Milton S. Hershey Medical Center

NCT06548490

RECRUITING Phase 2 180 participants

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

Brigham and Women's Hospital

NCT06376734

RECRUITING NA 150 participants

Transdiagnostic Behavior Therapy Vs TAU for Adjustment Disorder Following Traumatic Event Exposure

The University of Texas Health Science Center, Houston

NCT06433271

RECRUITING NA 100 participants

Enhancing Immune Health Randomized Controlled Trial

University of Illinois at Chicago

NCT05639881

RECRUITING NA 80 participants

Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use

Massachusetts General Hospital

NCT06878859

RECRUITING NA 60 participants

Healthy ReStart Intervention to Improve Health and Functioning

University of Illinois at Chicago

NCT05544344

RECRUITING NA 60 participants

Brain Stimulation to the Hippocampus in Schizophrenia

Stanford University

NCT07010614

RECRUITING 40 participants

Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside

Mclean Hospital

NCT05245903

RECRUITING NA 24 participants

ACT for HIV-Positive Men

University of Alabama at Birmingham

NCT06625437

ACTIVE NOT RECRUITING NA 750 participants

FCT Study: Reducing the Need for Out-of-Home Placements

Duke University

NCT03641664

ACTIVE NOT RECRUITING Phase 2 40 participants

Individualized Functional Connectivity Targeting in aiTBS for Depression

Brigham and Women's Hospital

NCT05680727

ACTIVE NOT RECRUITING Phase 2 15 participants

Psilocybin for the Treatment of Veterans With Post-Traumatic Stress Disorder

Ohio State University

NCT05554094

ACTIVE NOT RECRUITING Early Phase 1 10 participants

Testing a Transdiagnostic TMS Treatment Target

Brigham and Women's Hospital

NCT06282146

COMPLETED 2,400 participants

Mapping Personality Traits to Genes

National Institute of Mental Health (NIMH)

NCT00001414

COMPLETED NA 1,000 participants

Systems Aligning for Equity (SAFE) Spaces

New York University

NCT05658068

COMPLETED 450 participants

Safety Follow-up Study for Subjects With Agitation Associated With Dementia of the Alzheimer's Type Who Previously Participated in a Double-blind Trial of Brexpiprazole or Placebo

Otsuka Pharmaceutical Development & Commercialization

NCT02192554

COMPLETED Phase 3 433 participants

A Phase 3, 12-week, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy, Safety, and Tolerability of 2 Fixed Doses of Brexpiprazole in the Treatment of Alzheimer's Agitation

Otsuka Pharmaceutical Development & Commercialization

NCT01862640

COMPLETED Phase 3 270 participants

Safety and Tolerability Study of Flexible Dosing of Brexpiprazole in the Treatment of Subjects With Agitation Associated With Dementia of the Alzheimer's Type

Otsuka Pharmaceutical Development & Commercialization

NCT01922258

COMPLETED NA 234 participants

Peer Navigators to Address Obesity-Related Concerns for African Americans With Serious Mental Illness

Illinois Institute of Technology

NCT03382782

COMPLETED 150 participants

Neuropsychiatric Effects of Interferon-Alpha and Ribavirin

National Institute of Mental Health (NIMH)

NCT00001547

COMPLETED NA 108 participants

HIV/STI Prevention Among Black Adolescents With Mental Illnesses (Project GOLD)

University of Pennsylvania

NCT03348813

COMPLETED NA 74 participants

Family Promoting Positive Emotions Pilot Study

Vanderbilt University

NCT05223842

Phase Distribution

PhaseTrial count
Early Phase 1 1
Phase 2 4
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Mental Disorder Trial Landscape

ClinicalTrials.gov lists 22 US studies indexed under Mental Disorder, and 9 of those are currently open to recruitment — roughly 41% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Mental Disorder shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 5 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Mental Disorder is led by Otsuka Pharmaceutical Development & Commercialization with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 22 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Mental Disorder?

PlainTrial tracks 22 US clinical trials for Mental Disorder, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Mental Disorder?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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