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Malignant Neoplasm: early-phase trial registry
21 of 61 indexed Malignant Neoplasm trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #232 of 28,707 conditions by registered trial count.
61 US clinical trials · 21 currently recruiting · #232 of 28,707 conditions by registered trial count
Malignant Neoplasm: 61 US clinical trials tracked, 21 recruiting.
Malignant Neoplasm is the subject of 61 registered US clinical trials on ClinicalTrials.gov, 21 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 18 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 14 of these trials.
Enrollment posture brief
Registry condition malignant-neoplasm
OPEN 21 | RECR 34% | LATE 4 | EARLY 18 | RANK #232 | SPON 14
Volume-matched condition peers
Nearest open-share peer: Chronic Lymphocytic Leukemia (34% recruiting · 189 trials)
Malignant Neoplasm lists 21 open slots (34% of 61 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Malignant Neoplasm on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Malignant Neoplasm is recruiting below its size-band peers.
21 of 61 indexed trials (34.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Malignant Neoplasm research.
M.D. Anderson Cancer Center accounts for 14 of 61 trials (23%). 27 distinct sponsors appear on at least one study for this condition label.
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Typical Malignant Neoplasm enrolment sits around 118 participants.
Median target enrolment is 118 among the 60 trials that report a genuine target (sentinel values excluded). 25 of those (41.7%) plan for fewer than 100 participants.
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Malignant Neoplasm research is mostly interventional.
48 interventional and 13 observational studies make up this index (78.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
61 total, page 1 of 2
Molecular Genetics Studies of Cancer Patients and Their Relatives
City of Hope Medical Center
NCT04185935
Norris ORIEN Total Cancer Care
University of Southern California
NCT02970045
New Assessment System in Measuring Symptom Distress in Cancer Patients
M.D. Anderson Cancer Center
NCT00505245
Germ-Line Mutations in Blood and Saliva Samples From Patients With Cancer
Jonsson Comprehensive Cancer Center
NCT02280161
Targeted Genomic Analysis of Blood and Tissue Samples From Patients With Cancer
Rutgers, The State University of New Jersey
NCT02688517
Engagement of American Indians of Southwestern Tribal Nations in Cancer Genome Sequencing
New Mexico Cancer Research Alliance
NCT06207864
Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"
M.D. Anderson Cancer Center
NCT01365169
Collection of Immunology Specimens From Patients With Cancer or Blood Disorders, and Healthy Volunteers
University of Southern California
NCT03207854
A Study of TSN1611 Treating Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation
Tyligand Pharmaceuticals (Suzhou) Limited
NCT06385925
A Study to Evaluate the Safety and Efficacy of MK-3120 in Participants With Advanced Solid Tumors (MK-3120-002)
Merck Sharp & Dohme
NCT06818643
A Clinical Study of MK-4716 in People With Certain Solid Tumors (MK-4716-001)
Merck Sharp & Dohme
NCT07247110
A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)
Merck Sharp & Dohme
NCT06979596
Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain Metastases
M.D. Anderson Cancer Center
NCT03741673
Novel Outreach Methods to Increase Enrollment to Early Phase Clinical Trials
University of Chicago
NCT05886764
A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents
OncoResponse
NCT06090266
KEYMAKER-U01 Substudy 01J: A Study of Pembrolizumab Plus MK-1084 in Participants With Non-Small Cell Lung Cancer (NSCLC) With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) G12C Mutations (MK-3475-01J/KEYMAKER-U01J)
Merck Sharp & Dohme
NCT07252739
Cytotoxic T Lymphocytes in Treating Patients With Malignancies With BK and/or JC Virus
M.D. Anderson Cancer Center
NCT02479698
Intraoperative Tumor Margin Identification With ICG Dye Imaging
Massachusetts General Hospital
NCT04752137
Decreasing Chemotherapy Induced Distress Using Immersive Virtual Reality in Patients With Cancer
Case Comprehensive Cancer Center
NCT06446115
A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)
Merck Sharp & Dohme
NCT06941272
A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant
Jonsson Comprehensive Cancer Center
NCT04453072
Reproductive Health Program in Patients With Cancer
ECOG-ACRIN Cancer Research Group
NCT01806129
Use of a Pre-Surgical Toolkit in Improving Surgical Care and Outcomes in Older Participants With Cancer
Alliance for Clinical Trials in Oncology
NCT03857620
Molecular Profiling in Tissue Samples From Patients With Cancer Who Are Exceptional Responders to Treatment
National Cancer Institute (NCI)
NCT02243592
Novel Single Wave Assessment in Measuring Cardiac Dysfunction and Metabolic Syndrome in Patients With Cancer
City of Hope Medical Center
NCT04014231
Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease
M.D. Anderson Cancer Center
NCT01552434
Dexamethasone in Controlling Dyspnea in Patients With Cancer
M.D. Anderson Cancer Center
NCT03367156
Blood Samples to Identify Biomarkers in Patients Treated With Cyclophosphamide After Donor Stem Cell Transplant
City of Hope Medical Center
NCT04160390
rTMS in Improving Neuropathy in Patients With Stage I-IV Cancer Who Have Received Oxaliplatin Chemotherapy
M.D. Anderson Cancer Center
NCT03219502
Meditation Therapy in Improving Anxiety and Depression in Cancer Patients With Psychosocial Distress
M.D. Anderson Cancer Center
NCT02988271
Measuring Changes in Body Composition and Physical Function in Patients With Childhood Cancers
UNC Lineberger Comprehensive Cancer Center
NCT05823740
HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases
City of Hope Medical Center
NCT03696030
Web-Based Family Outreach Program for Cancer Prevention in High-Risk Families
M.D. Anderson Cancer Center
NCT02337452
Gene and Vaccine Therapy in Treating Patients With Advanced Malignancies
Jonsson Comprehensive Cancer Center
NCT01697527
Music in Reducing Distress in Participants with Cancer During Chemotherapy Treatment
Barbara Ann Karmanos Cancer Institute
NCT03683420
Yoga, Survivorship Health Education, and Cognitive Behavioral Therapy in Reducing Insomnia in Cancer Survivors
University of Rochester NCORP Research Base
NCT02613364
Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic Chemotherapy
Alliance for Clinical Trials in Oncology
NCT03578081
Multimedia Psychoeducation or Print Education in Preparing Cancer Patients for Decision Making About Clinical Trials
Gary Morrow
NCT02054715
Evidence-Based Tobacco Cessation Strategies in Patients With Cancer
Wake Forest University Health Sciences
NCT02211196
Apixaban or Dalteparin in Reducing Blood Clots in Patients With Cancer Related Venous Thromboembolism
Academic and Community Cancer Research United
NCT02585713
Videos and Questionnaires in Assessing Patient Perception of Physician's Compassion, Communication Skills, and Professionalism During Clinic Visits
M.D. Anderson Cancer Center
NCT03856060
Music Therapy Video Development in Improving Communication, Emotional Distress, and Recovery in Adolescents/Young Adults Undergoing Treatment for High-Risk Cancer and Their Parents
Children's Oncology Group
NCT01556256
Music Therapy or Book Discussion in Improving Quality of Life in Young Patients Undergoing Stem Cell Transplant
Children's Oncology Group
NCT00305851
A Survey of Parent/Caregiver Practices on the Storage, Use, and Disposal of Opioids in a Comprehensive Cancer Center
M.D. Anderson Cancer Center
NCT03390283
Palliative Radiation Therapy in Reducing Pain in Patients With Bone Metastasis
Wake Forest University Health Sciences
NCT02699697
Communication Effectiveness in Cancer Treatment
Wake Forest University Health Sciences
NCT02197091
Tailoring Patient Education to Perceived Risk for Falls in Hospitalized Oncology Patients
Case Comprehensive Cancer Center
NCT02081794
Low-Dose Ibuprofen in Improving Cognitive Impairment in Patients With Cancer
University of Rochester NCORP Research Base
NCT03186638
Factors Affecting Patient Participation in AIDS Malignancy Clinical Trials Consortium Clinical Trials
AIDS Malignancy Consortium
NCT01946217
Evaluation of Food Effect on Pharmacokinetics of Vismodegib
National Cancer Institute (NCI)
NCT01174264
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 8 |
| Phase 3 | 4 |
Top Sponsors
Named interventions
Most-linked intervention names on Malignant Neoplasm records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Malignant Neoplasm trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Malignant Neoplasm page
61 registered trials, 21 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 21 Malignant Neoplasm trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- M.D. Anderson Cancer Center sponsors the most Malignant Neoplasm trials on record, review their full trial history before evaluating a specific study. See M.D. Anderson Cancer Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Malignant Neoplasm condition card totals 61 registered trials; most-linked intervention Questionnaire Administration; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.