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Malignant Neoplasm clinical trials
Every US clinical trial registered for Malignant Neoplasm — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
61 US clinical trials · 21 currently recruiting
The research picture
Malignant Neoplasm has 61 registered US clinical trials, 21 of them open to new participants right now — about 34% of the total.
- 21
- recruiting participants now
- 34%
- of trials open to enrollment
- 4
- in Phase 3–4 (later-stage)
- 14
- top sponsor: M.D. Anderson Cancer Center
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Molecular Genetics Studies of Cancer Patients and Their Relatives
City of Hope Medical Center
NCT04185935
Norris ORIEN Total Cancer Care
University of Southern California
NCT02970045
New Assessment System in Measuring Symptom Distress in Cancer Patients
M.D. Anderson Cancer Center
NCT00505245
Germ-Line Mutations in Blood and Saliva Samples From Patients With Cancer
Jonsson Comprehensive Cancer Center
NCT02280161
Targeted Genomic Analysis of Blood and Tissue Samples From Patients With Cancer
Rutgers, The State University of New Jersey
NCT02688517
Engagement of American Indians of Southwestern Tribal Nations in Cancer Genome Sequencing
New Mexico Cancer Research Alliance
NCT06207864
Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"
M.D. Anderson Cancer Center
NCT01365169
Collection of Immunology Specimens From Patients With Cancer or Blood Disorders, and Healthy Volunteers
University of Southern California
NCT03207854
A Study of TSN1611 Treating Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation
Tyligand Pharmaceuticals (Suzhou) Limited
NCT06385925
A Study to Evaluate the Safety and Efficacy of MK-3120 in Participants With Advanced Solid Tumors (MK-3120-002)
Merck Sharp & Dohme
NCT06818643
A Clinical Study of MK-4716 in People With Certain Solid Tumors (MK-4716-001)
Merck Sharp & Dohme
NCT07247110
A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)
Merck Sharp & Dohme
NCT06979596
Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain Metastases
M.D. Anderson Cancer Center
NCT03741673
Novel Outreach Methods to Increase Enrollment to Early Phase Clinical Trials
University of Chicago
NCT05886764
A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents
OncoResponse
NCT06090266
KEYMAKER-U01 Substudy 01J: A Study of Pembrolizumab Plus MK-1084 in Participants With Non-Small Cell Lung Cancer (NSCLC) With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) G12C Mutations (MK-3475-01J/KEYMAKER-U01J)
Merck Sharp & Dohme
NCT07252739
Cytotoxic T Lymphocytes in Treating Patients With Malignancies With BK and/or JC Virus
M.D. Anderson Cancer Center
NCT02479698
Intraoperative Tumor Margin Identification With ICG Dye Imaging
Massachusetts General Hospital
NCT04752137
Decreasing Chemotherapy Induced Distress Using Immersive Virtual Reality in Patients With Cancer
Case Comprehensive Cancer Center
NCT06446115
A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)
Merck Sharp & Dohme
NCT06941272
A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant
Jonsson Comprehensive Cancer Center
NCT04453072
Reproductive Health Program in Patients With Cancer
ECOG-ACRIN Cancer Research Group
NCT01806129
Use of a Pre-Surgical Toolkit in Improving Surgical Care and Outcomes in Older Participants With Cancer
Alliance for Clinical Trials in Oncology
NCT03857620
Molecular Profiling in Tissue Samples From Patients With Cancer Who Are Exceptional Responders to Treatment
National Cancer Institute (NCI)
NCT02243592
Novel Single Wave Assessment in Measuring Cardiac Dysfunction and Metabolic Syndrome in Patients With Cancer
City of Hope Medical Center
NCT04014231
Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease
M.D. Anderson Cancer Center
NCT01552434
Dexamethasone in Controlling Dyspnea in Patients With Cancer
M.D. Anderson Cancer Center
NCT03367156
Blood Samples to Identify Biomarkers in Patients Treated With Cyclophosphamide After Donor Stem Cell Transplant
City of Hope Medical Center
NCT04160390
rTMS in Improving Neuropathy in Patients With Stage I-IV Cancer Who Have Received Oxaliplatin Chemotherapy
M.D. Anderson Cancer Center
NCT03219502
Meditation Therapy in Improving Anxiety and Depression in Cancer Patients With Psychosocial Distress
M.D. Anderson Cancer Center
NCT02988271
Measuring Changes in Body Composition and Physical Function in Patients With Childhood Cancers
UNC Lineberger Comprehensive Cancer Center
NCT05823740
HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases
City of Hope Medical Center
NCT03696030
Web-Based Family Outreach Program for Cancer Prevention in High-Risk Families
M.D. Anderson Cancer Center
NCT02337452
Gene and Vaccine Therapy in Treating Patients With Advanced Malignancies
Jonsson Comprehensive Cancer Center
NCT01697527
Music in Reducing Distress in Participants with Cancer During Chemotherapy Treatment
Barbara Ann Karmanos Cancer Institute
NCT03683420
Yoga, Survivorship Health Education, and Cognitive Behavioral Therapy in Reducing Insomnia in Cancer Survivors
University of Rochester NCORP Research Base
NCT02613364
Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic Chemotherapy
Alliance for Clinical Trials in Oncology
NCT03578081
Multimedia Psychoeducation or Print Education in Preparing Cancer Patients for Decision Making About Clinical Trials
Gary Morrow
NCT02054715
Evidence-Based Tobacco Cessation Strategies in Patients With Cancer
Wake Forest University Health Sciences
NCT02211196
Apixaban or Dalteparin in Reducing Blood Clots in Patients With Cancer Related Venous Thromboembolism
Academic and Community Cancer Research United
NCT02585713
Videos and Questionnaires in Assessing Patient Perception of Physician's Compassion, Communication Skills, and Professionalism During Clinic Visits
M.D. Anderson Cancer Center
NCT03856060
Music Therapy Video Development in Improving Communication, Emotional Distress, and Recovery in Adolescents/Young Adults Undergoing Treatment for High-Risk Cancer and Their Parents
Children's Oncology Group
NCT01556256
Music Therapy or Book Discussion in Improving Quality of Life in Young Patients Undergoing Stem Cell Transplant
Children's Oncology Group
NCT00305851
A Survey of Parent/Caregiver Practices on the Storage, Use, and Disposal of Opioids in a Comprehensive Cancer Center
M.D. Anderson Cancer Center
NCT03390283
Palliative Radiation Therapy in Reducing Pain in Patients With Bone Metastasis
Wake Forest University Health Sciences
NCT02699697
Communication Effectiveness in Cancer Treatment
Wake Forest University Health Sciences
NCT02197091
Tailoring Patient Education to Perceived Risk for Falls in Hospitalized Oncology Patients
Case Comprehensive Cancer Center
NCT02081794
Low-Dose Ibuprofen in Improving Cognitive Impairment in Patients With Cancer
University of Rochester NCORP Research Base
NCT03186638
Factors Affecting Patient Participation in AIDS Malignancy Clinical Trials Consortium Clinical Trials
AIDS Malignancy Consortium
NCT01946217
Evaluation of Food Effect on Pharmacokinetics of Vismodegib
National Cancer Institute (NCI)
NCT01174264
Netupitant and Palonosetron Hydrochloride in Preventing Chronic Nausea and Vomiting in Patients With Cancer
M.D. Anderson Cancer Center
NCT03040726
Meditative Slow Breathing or Isha Kriya Meditation in Improving Cancer-Related Symptoms in Hospitalized Participants With Cancer
M.D. Anderson Cancer Center
NCT03445572
Sensory Evaluation of Oral Nutrition Supplements in Patients at Risk for Mucositis Undergoing Cancer Treatment
Rutgers, The State University of New Jersey
NCT03228147
Psycho-Educational Program in Increasing Knowledge and Satisfaction and Decreasing Distress in Younger Patients With Cancer Receiving Treatment
City of Hope Medical Center
NCT01817335
A Computer-Based System for Symptom Reporting in Patients With Cancer Undergoing Treatment
Thomas Jefferson University
NCT03979846
Scrambler Therapy for the Reduction of Chemotherapy-Induced Neuropathic Pain
M.D. Anderson Cancer Center
NCT04239976
Extended Use of Sodium Bicarbonate in Patients With Cancer
University of Arizona
NCT02531919
Bovine Lactoferrin Supplement in Improving Taste in Patients With Cancer Receiving Chemotherapy
Wake Forest University Health Sciences
NCT01941810
Short-Term Fasting Before Chemotherapy in Treating Patients With Cancer
Mayo Clinic
NCT01175837
SPECT/CT in Measuring Lung Function in Patients With Cancer Undergoing Radiation Therapy
University of Washington
NCT01982123
Curcumin and Piperine in Reducing Inflammation for Ureteral Stent-Induced Symptoms in Patients With Cancer
Mayo Clinic
NCT02598726
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 8 |
| Phase 3 | 4 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Malignant Neoplasm Trial Landscape
ClinicalTrials.gov lists 61 US studies indexed under Malignant Neoplasm, and 21 of those are currently open to recruitment — roughly 34% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Malignant Neoplasm shows 4 late-stage studies (Phase 3 and Phase 4 combined) alongside 18 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Malignant Neoplasm is led by M.D. Anderson Cancer Center with 14 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 61 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Malignant Neoplasm?
PlainTrial tracks 61 US clinical trials for Malignant Neoplasm, of which 21 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Malignant Neoplasm?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.