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A Study to Evaluate the Safety and Efficacy of MK-3120 in Participants With Advanced Solid Tumors (MK-3120-002)
NCT06818643 · View on ClinicalTrials.gov ↗
Study Summary
Researchers are looking for new ways to treat people with certain advanced solid tumors. Advanced means the cancer has spread to other parts of the body and cannot be removed with surgery. Solid tumors are cancers mostly in body organs and tissues, not in the blood or other body liquids. The main goal of this study is to learn about the safety of MK-3120 and if people tolerate it.
Conditions Studied
Interventions
- BIOLOGICAL MK-3120
Study Locations (20)
Region M. de Santiago
- Centro de Estudios Clínicos SAGA ( Site 0033) — Santiago
- FALP ( Site 0031) — Santiago
- Pontificia Universidad Catolica de Chile ( Site 0032) — Santiago
- Bradford Hill Centro de Investigaciones Clinicas ( Site 0030) — Santiago
Other
- Rambam Health Care Campus ( Site 0082) — Haifa
- Rabin Medical Center ( Site 0081) — Petah Tikva
- Sheba Medical Center ( Site 0080) — Ramat Gan
Alabama
- The University of Alabama at Birmingham ( Site 1005) — Birmingham
Florida
- University of Miami Hospital and Clinics, Sylvester Cancer Center ( Site 1003) — Miami
New Jersey
- John Theurer Cancer Center at Hackensack University Medical Center ( Site 1009) — Hackensack
Virginia
- Virginia Commonwealth University ( Site 1008) — Richmond
Beijing Municipality
- Peking University First Hospital ( Site 0180) — Beijing
Chongqing Municipality
- Chongqing Cancer Hospital ( Site 0186) — Chongqing
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 270 participants |
| Start Date | 2025-03-25 |
| Est. Completion | 2031-03-25 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06818643
The ClinicalTrials.gov registry entry for NCT06818643 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 270 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Merck Sharp & Dohme, which has 741 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Advanced Solid Tumors appearing as the primary indexed condition, and to 1 intervention — of which MK-3120 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06818643 reports 20 study locations spanning 15 distinct geographic areas — top geographies include Region M. de Santiago, Other, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06818643 about?
NCT06818643 is a clinical study titled "A Study to Evaluate the Safety and Efficacy of MK-3120 in Participants With Advanced Solid Tumors (MK-3120-002)". Researchers are looking for new ways to treat people with certain advanced solid tumors. Advanced means the cancer has spread to other parts of the body and cannot be removed with surgery. Solid tumors are cancers mostly in body organs and tissues, not in the blood or other body liquids. The main go...
What is the current status of trial NCT06818643?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 270 participants. The study started on 2025-03-25. Estimated completion is 2031-03-25.
What conditions does trial NCT06818643 study?
This clinical trial studies the following conditions: Advanced Solid Tumors, Malignant Neoplasm. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06818643?
The interventions under investigation include: MK-3120 (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06818643?
This trial is sponsored by Merck Sharp & Dohme, which has 741 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06818643 being conducted?
This trial has 20 study locations across Alabama, Florida, New Jersey, Virginia, Region M. de Santiago. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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