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Low-Dose Ibuprofen in Improving Cognitive Impairment in Patients With Cancer
NCT03186638 · View on ClinicalTrials.gov ↗
Study Summary
This randomized phase II trial studies how well low-dose ibuprofen in improving cognitive impairment in patients with cancer. Anti-inflammatory agents, such as ibuprofen, may slow the decline of cognitive processes and diseases involving the brain.
Conditions Studied
Interventions
- OTHER Placebo
- OTHER Questionnaire Administration
- DRUG Ibuprofen
Study Locations (20)
Delaware
- Beebe Medical Center — Lewes
- Delaware Clinical and Laboratory Physicians PA — Newark
- Helen F Graham Cancer Center — Newark
- Medical Oncology Hematology Consultants PA — Newark
- Regional Hematology and Oncology PA — Newark
- Christiana Care Health System-Christiana Hospital — Newark
- Beebe Health Campus — Rehoboth Beach
- Nanticoke Memorial Hospital — Seaford
- Christiana Care Health System-Wilmington Hospital — Wilmington
Idaho
- Saint Luke's Mountain States Tumor Institute — Boise
- Saint Luke's Mountain States Tumor Institute - Fruitland — Fruitland
- Saint Luke's Mountain States Tumor Institute - Meridian — Meridian
- Saint Luke's Mountain States Tumor Institute - Nampa — Nampa
- Saint Luke's Mountain States Tumor Institute-Twin Falls — Twin Falls
Illinois
- Illinois CancerCare-Bloomington — Bloomington
- Illinois CancerCare-Canton — Canton
- Memorial Hospital of Carbondale — Carbondale
- SIH Cancer Institute — Carterville
- Illinois CancerCare-Carthage — Carthage
California
- Providence Saint Joseph Medical Center/Disney Family Cancer Center — Burbank
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 87 participants |
| Start Date | 2017-05-26 |
| Est. Completion | 2022-06-01 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03186638
The ClinicalTrials.gov registry entry for NCT03186638 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 87 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Rochester NCORP Research Base, which has 8 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Cognitive Impairment appearing as the primary indexed condition, and to 3 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT03186638 reports 20 study locations spanning 4 distinct geographic areas — top geographies include Delaware, Idaho, Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT03186638 about?
NCT03186638 is a clinical study titled "Low-Dose Ibuprofen in Improving Cognitive Impairment in Patients With Cancer". This randomized phase II trial studies how well low-dose ibuprofen in improving cognitive impairment in patients with cancer. Anti-inflammatory agents, such as ibuprofen, may slow the decline of cognitive processes and diseases involving the brain.
What is the current status of trial NCT03186638?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 87 participants. The study started on 2017-05-26. Estimated completion is 2022-06-01.
What conditions does trial NCT03186638 study?
This clinical trial studies the following conditions: Cognitive Impairment, Malignant Neoplasm. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT03186638?
The interventions under investigation include: Placebo (OTHER), Questionnaire Administration (OTHER), Ibuprofen (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT03186638?
This trial is sponsored by University of Rochester NCORP Research Base, which has 8 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT03186638 being conducted?
This trial has 20 study locations across California, Delaware, Idaho, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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