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NCT03741673 · ClinicalTrials.gov registry record · Phase 3
Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain Metastases
A Phase 3 study of Malignant Neoplasm and Metastatic Malignant Neoplasm in the Brain, sponsored by M.D. Anderson Cancer Center.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 180
- Enrollment target
- 1
- Study location
NCT03741673: Recruiting Phase 3 study of Malignant Neoplasm and Metastatic Malignant Neoplasm in the Brain, sponsored by M.D. Anderson Cancer Center.
NCT03741673 is a Phase 3 study of Malignant Neoplasm and Metastatic Malignant Neoplasm in the Brain that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 180 participants, below the 510-participant average among 59 other Malignant Neoplasm trials with a reported enrollment target (65% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03741673, a Phase 3 study of Malignant Neoplasm and Metastatic Malignant Neoplasm in the Brain, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 180 participants
- Enrollment target
- 1
- Study location
Study Summary
This phase III trial studies stereotactic radiosurgery (SRS) before surgery to see how well it works compared with SRS after surgery in treating patients with cancer that has spread to the brain (brain metastases). SRS is the delivery of focused, high-dose radiation given in a single session to the tumors, with a minimal dose given to uninvolved areas of the brain.
Primary Outcome
Aalen-Johansen estimates will be used for LMD. Uni- and multi-variable analysis of time to LMD will be done using Fine-Gray proportional hazards regression. Model assumptions will be verified graphically by residual analyses.
Conditions Studied
Interventions
- OTHER Quality-of-Life Assessment
- OTHER Questionnaire Administration
- RADIATION Stereotactic Radiosurgery
Study Locations (1)
Texas
- M D Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2018-11-08 |
| Est. Completion | 2027-01-31 |
| Phase | Phase 3 |
What NCT03741673 shows while recruiting
NCT03741673 is an interventional study that assigns participants to a tested intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, below the 510-participant average among 59 other Malignant Neoplasm trials with a reported enrollment target (65% lower).
The record links to 2 conditions, with Malignant Neoplasm appearing as the primary indexed condition, and to 3 interventions - of which Quality-of-Life Assessment is the first listed.
NCT03741673 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT03741673 about?
NCT03741673 is a clinical study titled "Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain Metastases". This phase III trial studies stereotactic radiosurgery (SRS) before surgery to see how well it works compared with SRS after surgery in treating patients with cancer that has spread to the brain (brain metastases). SRS is the delivery of focused, high-dose radiation given in a single session to the ...
What is the current status of trial NCT03741673?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 180 participants. The study started on 2018-11-08. Estimated completion is 2027-01-31.
What conditions does trial NCT03741673 study?
This clinical trial studies the following conditions: Malignant Neoplasm, Metastatic Malignant Neoplasm in the Brain.
What interventions are being tested in trial NCT03741673?
The interventions under investigation include: Quality-of-Life Assessment (OTHER), Questionnaire Administration (OTHER), Stereotactic Radiosurgery (RADIATION).
Who is sponsoring clinical trial NCT03741673?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03741673 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Malignant Neoplasm
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03741673's enrollment target sits among peer trials
180 20th of 59 higher than 39 of 59 other Malignant Neoplasm trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Malignant Neoplasm trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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