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ClinicalTrials.gov 12 recruiting now official registry

Lymphoma, B-Cell clinical trials

12 of 32 indexed Lymphoma, B-Cell trials are currently recruiting.

32 US clinical trials · 12 currently recruiting

Lymphoma, B-Cell is the subject of 32 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 24 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 3 of these trials.

The research picture

Lymphoma, B-Cell has 32 registered US clinical trials, 12 of them open to new participants right now, about 38% of the total.

12
recruiting participants now
38%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
3
top sponsor: Memorial Sloan Kettering Cancer Center
Phase 118Phase 26Phase 31Phase 41

Active & Recent Trials

32 total, page 1 of 1

RECRUITING 3,000 participants

Family Study of Lymphoproliferative Disorders

Mayo Clinic

NCT00626496

RECRUITING Phase 1 439 participants

A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma

Janssen Research & Development

NCT05421663

RECRUITING Phase 3 400 participants

A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

Lyell Immunopharma

NCT07188558

RECRUITING Phase 1 180 participants

A Phase 1/2 Study of STP938 for Adult Subjects With Relapsed/Refractory B-Cell and T-Cell Lymphomas

Step Pharma, SAS

NCT05463263

RECRUITING Phase 1 174 participants

Study of Safety and Efficacy of Iberdomide (CC-220) and CC-99282 Combined With R-CHOP to Treat Lymphoma

Celgene

NCT04884035

RECRUITING 154 participants

Study of CAR-T Therapy in Older Patients

Memorial Sloan Kettering Cancer Center

NCT04300998

RECRUITING Phase 1 106 participants

A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies

Umoja Biopharma

NCT06528301

RECRUITING Phase 1 54 participants

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

Therapeutic Advances in Childhood Leukemia Consortium

NCT05476770

RECRUITING NA 48 participants

Study of a Communication Training Intervention for Large B-Cell Lymphoma Providers

Memorial Sloan Kettering Cancer Center

NCT05940272

RECRUITING NA 40 participants

ctDNA-guided Therapy Optimization in Newly Diagnosed DLBCL

Hua-Jay J Cherng, MD

NCT06693830

RECRUITING Phase 2 30 participants

Defining ctDNA Metrics in Posttransplant Lymphoproliferative Disorder (PTLD)

Jennifer Amengual

NCT06954805

RECRUITING Phase 1 24 participants

Phase 1 Trial of BTM-3566 in Relapsed/Refractory Mature B Cell Lymphomas

Bantam Pharmaceuticals

NCT06792734

ACTIVE NOT RECRUITING Phase 4 297 participants

Extended Treatment Protocol for Subjects Continuing to Benefit From Ibrutinib.

Pharmacyclics Switzerland

NCT03229200

ACTIVE NOT RECRUITING Phase 1 190 participants

A Study of Nemtabrutinib (MK-1026) in Participants With Relapsed or Refractory Hematologic Malignancies (ARQ 531-101/MK-1026-001)

ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA)

NCT03162536

ACTIVE NOT RECRUITING Phase 1 58 participants

Trial of Anti-CD19 and Anti-CD20 Bicistronic Chimeric Antigen Receptor T Cells for Treating B-Cell Malignancies

National Cancer Institute (NCI)

NCT05797233

ACTIVE NOT RECRUITING Phase 1 54 participants

FT819 in Subjects With B-cell Malignancies

Fate Therapeutics

NCT04629729

ACTIVE NOT RECRUITING Phase 2 51 participants

Pembrolizumab in Combination With Chemotherapy for Patients With Untreated B Cell Lymphoma

University of Chicago

NCT03995147

ACTIVE NOT RECRUITING Phase 1 39 participants

A Study of Melphalan in People With Lymphoma Getting an Autologous Hematopoietic Cell Transplant

Memorial Sloan Kettering Cancer Center

NCT05540340

ACTIVE NOT RECRUITING Phase 2 39 participants

A Study of Polatuzumab Vedotin, Rituximab and Dose Attenuated CHP in Older Patients With DLBCL

University of Rochester

NCT04594798

ACTIVE NOT RECRUITING Phase 1 19 participants

Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma

UNC Lineberger Comprehensive Cancer Center

NCT03696784

COMPLETED Phase 2 279 participants

Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)

National Heart, Lung, and Blood Institute (NHLBI)

NCT02208037

COMPLETED Phase 1 137 participants

Study to Evaluate the Safety and Efficacy of a Combination of Favezelimab (MK-4280) and Pembrolizumab (MK-3475) in Participants With Hematologic Malignancies (MK-4280-003)

Merck Sharp & Dohme

NCT03598608

COMPLETED Phase 1 103 participants

Study Evaluating Chemotherapy in Combination With Inotuzumab Ozogamicin In Subjects With Non-Hodgkin's Lymphoma

Pfizer

NCT01055496

COMPLETED Phase 2 64 participants

Study Evaluating Inotuzumab Ozogamicin (CMC-544) Plus Rituximab In Diffuse Large B-Cell Non-Hodgkin's Lymphoma

Pfizer

NCT00867087

COMPLETED Phase 2 55 participants

Bone Marrow Transplant From Partially Matched Donors and Nonmyeloablative Conditioning for Blood Cancers (BMT CTN 0603)

Medical College of Wisconsin

NCT00849147

COMPLETED NA 45 participants

Evaluating the Feasibility of a Digital Health Coaching Program for Individuals Following CAR T Therapy

Pack Health

NCT05064787

COMPLETED Phase 1 37 participants

A Phase I/II Trial of VR-CHOP in Lymphoma Patients

Emory University

NCT00634179

COMPLETED Phase 1 33 participants

Clofarabine for Relapsed or Refractory T-Cell or B-Cell Non-Hodgkin Lymphoma (NHL)

Oncology Specialists, S.C.

NCT00156013

COMPLETED Phase 1 32 participants

Study of TRPH-222 in Patients With Relapsed and/or Refractory B-Cell Lymphoma

Triphase Research and Development III

NCT03682796

COMPLETED Phase 1 27 participants

T Cells Expressing a Fully-human AntiCD19 Chimeric Antigen Receptor for Treating B-cell Malignancies

National Cancer Institute (NCI)

NCT02659943

COMPLETED Phase 1 23 participants

The Safety, Pharmacokinetic and Pharmacodynamic Effect of KA2237 (PI3 Kinase p110β/δ Inhibitor) In B Cell Lymphoma

Karus Therapeutics Limited

NCT02679196

COMPLETED NA 10 participants

Adaptive Bridging RT in R/R B-cell Lymphoma (Pre-CAR T)

Massachusetts General Hospital

NCT06004167

Phase Distribution

PhaseTrial count
Phase 1 18
Phase 2 6
Phase 3 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Lymphoma, B-Cell Trial Landscape

32 indexed Lymphoma, B-Cell studies · 12 recruiting (38%).

Phase mix: 2 late (III/IV) vs 24 early (I/II).

Top sponsor: Memorial Sloan Kettering Cancer Center (3 trials), 9 others listed. 32 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Lymphoma, B-Cell?

PlainTrial tracks 32 US clinical trials for Lymphoma, B-Cell, of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Lymphoma, B-Cell?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.