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ClinicalTrials.gov 12 recruiting now early-phase tilt

Lymphoma, B-Cell: early-phase trial registry

12 of 32 indexed Lymphoma, B-Cell trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #477 of 28,707 conditions by registered trial count.

32 US clinical trials · 12 currently recruiting · #477 of 28,707 conditions by registered trial count

Lymphoma, B-Cell: 32 US clinical trials tracked, 12 recruiting.

Lymphoma, B-Cell is the subject of 32 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 24 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 3 of these trials.

Enrollment posture brief

Registry condition lymphoma-b-cell

OPEN 12 | RECR 38% | LATE 2 | EARLY 24 | RANK #477 | SPON 3

Nearest open-share peer: Acute-graft-versus-host Disease (38% recruiting · 8 trials)

Acute Respiratory Distress S43.8%Lymphoma, B-Cell (this)38%Cardiac Arrest37.5%Astigmatism28.1%Cardiovascular Risk Factor21.9%
Open-enrollment share among volume-matched conditions near Lymphoma, B-Cell

Lymphoma, B-Cell lists 12 open slots (38% of 32 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Lymphoma, B-Cell on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Lymphoma, B-Cell is recruiting below its size-band peers.

    12 of 32 indexed trials (37.5%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Lymphoma, B-Cell trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 3 of 32 trials (9.4%). 28 distinct sponsors appear on at least one study for this condition label.

  3. Most Lymphoma, B-Cell trials plan to enrol fewer than 100 people.

    Median target enrolment is 54 among the 32 trials that report a genuine target (sentinel values excluded). 20 of those (62.5%) plan for fewer than 100 participants.

  4. Lymphoma, B-Cell research is mostly interventional.

    30 interventional and 2 observational studies make up this index (93.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 118Phase 26Phase 31Phase 41

Open and recent trials

32 total, page 1 of 1

RECRUITING 3,000 participants

Family Study of Lymphoproliferative Disorders

Mayo Clinic

NCT00626496

RECRUITING Phase 1 439 participants

A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma

Janssen Research & Development

NCT05421663

RECRUITING Phase 3 400 participants

A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

Lyell Immunopharma

NCT07188558

RECRUITING Phase 1 180 participants

A Phase 1/2 Study of STP938 for Adult Subjects With Relapsed/Refractory B-Cell and T-Cell Lymphomas

Step Pharma, SAS

NCT05463263

RECRUITING Phase 1 174 participants

Study of Safety and Efficacy of Iberdomide (CC-220) and CC-99282 Combined With R-CHOP to Treat Lymphoma

Celgene

NCT04884035

RECRUITING 154 participants

Study of CAR-T Therapy in Older Patients

Memorial Sloan Kettering Cancer Center

NCT04300998

RECRUITING Phase 1 106 participants

A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies

Umoja Biopharma

NCT06528301

RECRUITING Phase 1 54 participants

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

Therapeutic Advances in Childhood Leukemia Consortium

NCT05476770

RECRUITING NA 48 participants

Study of a Communication Training Intervention for Large B-Cell Lymphoma Providers

Memorial Sloan Kettering Cancer Center

NCT05940272

RECRUITING NA 40 participants

ctDNA-guided Therapy Optimization in Newly Diagnosed DLBCL

Hua-Jay J Cherng, MD

NCT06693830

RECRUITING Phase 2 30 participants

Defining ctDNA Metrics in Posttransplant Lymphoproliferative Disorder (PTLD)

Jennifer Amengual

NCT06954805

RECRUITING Phase 1 24 participants

Phase 1 Trial of BTM-3566 in Relapsed/Refractory Mature B Cell Lymphomas

Bantam Pharmaceuticals

NCT06792734

ACTIVE NOT RECRUITING Phase 4 297 participants

Extended Treatment Protocol for Subjects Continuing to Benefit From Ibrutinib.

Pharmacyclics Switzerland

NCT03229200

ACTIVE NOT RECRUITING Phase 1 190 participants

A Study of Nemtabrutinib (MK-1026) in Participants With Relapsed or Refractory Hematologic Malignancies (ARQ 531-101/MK-1026-001)

ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA)

NCT03162536

ACTIVE NOT RECRUITING Phase 1 58 participants

Trial of Anti-CD19 and Anti-CD20 Bicistronic Chimeric Antigen Receptor T Cells for Treating B-Cell Malignancies

National Cancer Institute (NCI)

NCT05797233

ACTIVE NOT RECRUITING Phase 1 54 participants

FT819 in Subjects With B-cell Malignancies

Fate Therapeutics

NCT04629729

ACTIVE NOT RECRUITING Phase 2 51 participants

Pembrolizumab in Combination With Chemotherapy for Patients With Untreated B Cell Lymphoma

University of Chicago

NCT03995147

ACTIVE NOT RECRUITING Phase 1 39 participants

A Study of Melphalan in People With Lymphoma Getting an Autologous Hematopoietic Cell Transplant

Memorial Sloan Kettering Cancer Center

NCT05540340

ACTIVE NOT RECRUITING Phase 2 39 participants

A Study of Polatuzumab Vedotin, Rituximab and Dose Attenuated CHP in Older Patients With DLBCL

University of Rochester

NCT04594798

ACTIVE NOT RECRUITING Phase 1 19 participants

Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma

UNC Lineberger Comprehensive Cancer Center

NCT03696784

COMPLETED Phase 2 279 participants

Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)

National Heart, Lung, and Blood Institute (NHLBI)

NCT02208037

COMPLETED Phase 1 137 participants

Study to Evaluate the Safety and Efficacy of a Combination of Favezelimab (MK-4280) and Pembrolizumab (MK-3475) in Participants With Hematologic Malignancies (MK-4280-003)

Merck Sharp & Dohme

NCT03598608

COMPLETED Phase 1 103 participants

Study Evaluating Chemotherapy in Combination With Inotuzumab Ozogamicin In Subjects With Non-Hodgkin's Lymphoma

Pfizer

NCT01055496

COMPLETED Phase 2 64 participants

Study Evaluating Inotuzumab Ozogamicin (CMC-544) Plus Rituximab In Diffuse Large B-Cell Non-Hodgkin's Lymphoma

Pfizer

NCT00867087

COMPLETED Phase 2 55 participants

Bone Marrow Transplant From Partially Matched Donors and Nonmyeloablative Conditioning for Blood Cancers (BMT CTN 0603)

Medical College of Wisconsin

NCT00849147

COMPLETED NA 45 participants

Evaluating the Feasibility of a Digital Health Coaching Program for Individuals Following CAR T Therapy

Pack Health

NCT05064787

COMPLETED Phase 1 37 participants

A Phase I/II Trial of VR-CHOP in Lymphoma Patients

Emory University

NCT00634179

COMPLETED Phase 1 33 participants

Clofarabine for Relapsed or Refractory T-Cell or B-Cell Non-Hodgkin Lymphoma (NHL)

Oncology Specialists, S.C.

NCT00156013

COMPLETED Phase 1 32 participants

Study of TRPH-222 in Patients With Relapsed and/or Refractory B-Cell Lymphoma

Triphase Research and Development III

NCT03682796

COMPLETED Phase 1 27 participants

T Cells Expressing a Fully-human AntiCD19 Chimeric Antigen Receptor for Treating B-cell Malignancies

National Cancer Institute (NCI)

NCT02659943

COMPLETED Phase 1 23 participants

The Safety, Pharmacokinetic and Pharmacodynamic Effect of KA2237 (PI3 Kinase p110β/δ Inhibitor) In B Cell Lymphoma

Karus Therapeutics Limited

NCT02679196

COMPLETED NA 10 participants

Adaptive Bridging RT in R/R B-cell Lymphoma (Pre-CAR T)

Massachusetts General Hospital

NCT06004167

Phase Distribution

PhaseTrial count
Phase 1 18
Phase 2 6
Phase 3 1
Phase 4 1

Named interventions

Most-linked intervention names on Lymphoma, B-Cell records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Cyclophosphamide Drug
8 trials
Fludarabine Drug
5 trials
Vincristine Drug
4 trials
Rituximab Drug
3 trials
Doxorubicin Drug
3 trials
Bendamustine Drug
2 trials
Prednisone Drug
2 trials
Favezelimab Biological
1 trials

US sites by state

Facility locations filed on Lymphoma, B-Cell trials. A trial with sites in several states counts in each.

New York 14 trials
California 12 trials
Texas 11 trials
Illinois 8 trials
Florida 8 trials
North Carolina 7 trials
Massachusetts 7 trials
Pennsylvania 6 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Lymphoma, B-Cell page

32 registered trials, 12 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Lymphoma, B-Cell condition card totals 32 registered trials; most-linked intervention Cyclophosphamide; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.