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ClinicalTrials.gov 3 recruiting now early-phase tilt small index

Acute-graft-versus-host Disease: early-phase trial registry

3 of 8 indexed Acute-graft-versus-host Disease trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #2,176 of 28,707 conditions by registered trial count.

8 US clinical trials · 3 currently recruiting · #2,176 of 28,707 conditions by registered trial count

Acute-graft-versus-host Disease: 8 US clinical trials tracked, 3 recruiting.

Acute-graft-versus-host Disease is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Regimmune Corporation, running 1 of these trials.

Enrollment posture brief

Registry condition acute-graft-versus-host-disease

OPEN 3 | RECR 38% | LATE 1 | EARLY 5 | RANK #2176 | SPON 1

Nearest open-share peer: Acute Lymphoid Leukemia (38% recruiting · 8 trials)

Activity, Motor75%Achalasia50%Acute-graft-versus-host (th…38%Abdominal Cancer25%Acne Scars - Mixed Atrophic 25%
Open-enrollment share among volume-matched conditions near Acute-graft-versus-host Disease

Acute-graft-versus-host Disease lists 3 open slots (38% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Acute-graft-versus-host Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Acute-graft-versus-host Disease is recruiting below its size-band peers.

    3 of 8 indexed trials (37.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Acute-graft-versus-host Disease trials is spread across many organizations.

    Regimmune Corporation accounts for 1 of 8 trials (12.5%). 8 distinct sponsors appear on at least one study for this condition label.

  3. Most Acute-graft-versus-host Disease trials plan to enrol fewer than 100 people.

    Median target enrolment is 98 among the 8 trials that report a genuine target (sentinel values excluded). 5 of those (62.5%) plan for fewer than 100 participants.

  4. Acute-graft-versus-host Disease research is mostly interventional.

    7 interventional and 1 observational studies make up this index (87.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 24Phase 31

Open and recent trials

8 total, page 1 of 1

RECRUITING Phase 2 98 participants

MAGIC Ruxolitinib for aGVHD

John Levine

NCT06936566

RECRUITING NA 36 participants

Impact of Exercise on the Complications of Corticosteroids in Patients With GVHD: the RESTART Trial

Dana-Farber Cancer Institute

NCT05236062

RECRUITING Phase 1 18 participants

Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Donor Stem Cell Transplant for Hematologic Malignancies

City of Hope Medical Center

NCT05443425

ACTIVE NOT RECRUITING Phase 2 222 participants

The Safety and Efficacy of Alpha-1 Antitrypsin (AAT) for the Prevention of Graft-versus-host Disease (GVHD) in Patients Receiving Hematopoietic Cell Transplant

CSL Behring

NCT03805789

ACTIVE NOT RECRUITING Phase 3 173 participants

Lactobacillus Plantarum in Preventing Acute Graft Versus Host Disease in Children Undergoing Donor Stem Cell Transplant

Children's Oncology Group

NCT03057054

ACTIVE NOT RECRUITING Phase 2 138 participants

Fecal Microbiota Transplantation for the Prevention of Acute Graft Versus Host Disease in Adults Undergoing Allogeneic Hematopoietic Cell Transplantation

Fred Hutchinson Cancer Center

NCT06026371

ACTIVE NOT RECRUITING 22 participants

Dendritic Cells in Patients With Acute or Chronic Skin Graft Versus Host Disease

Washington University School of Medicine

NCT02611180

COMPLETED Phase 2 49 participants

RGI-2001 for the Prevention of Acute Graft-vs-Host Disease in Subjects Following Allogeneic Hematopoietic Stem Cell Transplantation

Regimmune Corporation

NCT04014790

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 4
Phase 3 1

Named interventions

Most-linked intervention names on Acute-graft-versus-host Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

RGI-2001 Drug
1 trials
AAT Biological
1 trials
Lactobacillus plantarum strain 299v Biological
1 trials
Lactobacillus plantarum strain 299 Biological
1 trials
Skin punch biopsy Procedure
1 trials
Placebo Administration Other
1 trials
Peripheral blood draw Procedure
1 trials
Fecal Microbiota Transplantation Capsule Drug
1 trials

US sites by state

Facility locations filed on Acute-graft-versus-host Disease trials. A trial with sites in several states counts in each.

Massachusetts 5 trials
Florida 4 trials
California 4 trials
Washington 3 trials
Ohio 3 trials
Michigan 3 trials
Texas 2 trials
New York 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Acute-graft-versus-host Disease page

8 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 3 Acute-graft-versus-host Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Regimmune Corporation sponsors the most Acute-graft-versus-host Disease trials on record, review their full trial history before evaluating a specific study. See Regimmune Corporation's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Acute-graft-versus-host Disease condition card totals 8 registered trials; most-linked intervention RGI-2001; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.