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NCT00849147 · ClinicalTrials.gov registry record · Phase 2

Bone Marrow Transplant From Partially Matched Donors and Nonmyeloablative Conditioning for Blood Cancers (BMT CTN 0603)

A Phase 2 study of Lymphoma, B-Cell and Leukemia, Myeloid, Acute, sponsored by Medical College of Wisconsin.

Completed
Registry status
Phase 2
Development phase
55
Enrollment target
17
Study locations

NCT00849147 is a Phase 2 study of Lymphoma, B-Cell and Leukemia, Myeloid, Acute that has completed, run by Medical College of Wisconsin. The registered enrollment target is 55 participants, below the 200-participant average among 31 other Lymphoma, B-Cell trials with a reported enrollment target (72% lower). The trial reports 17 study locations across 14 states.

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The verdict

NCT00849147, a Phase 2 study of Lymphoma, B-Cell and Leukemia, Myeloid, Acute, has completed, sponsored by Medical College of Wisconsin.

COMPLETED
Registry status
Phase 2
Development phase
55 participants
Enrollment target
17
Study locations

Study Summary

Bone marrow transplants are one treatment option for people with leukemia or lymphoma. Family members or unrelated donors with a similar type of bone marrow usually donate their bone marrow to the transplant patients. This study will evaluate the effectiveness of a new type of bone marrow transplant-one that uses lower doses of chemotherapy and bone marrow donated from family members with only partially matched bone marrow-in people with leukemia or lymphoma.

Interventions

  • BIOLOGICAL Haploidentical Bone Marrow Transplantation
  • BIOLOGICAL GVHD prophylaxis

Study Locations (17)

California

  • City of Hope National Medical Center - Duarte
  • University of California San Diego Medical Center - La Jolla

Maryland

  • University of Maryland, Greenbaum Cancer Center - Baltimore
  • Johns Hopkins University/Sidney Kimmel Comprehensive Cancer Center (SKCCC) - Baltimore

Texas

  • Baylor University Medical Center - Dallas
  • Texas Transplant Institute - San Antonio

Florida

  • University of Florida College of Medicine (Shands) - Gainesville

Georgia

  • Bone Marrow Transplant Group of Georgia, Northside Hospital - Atlanta

Hawaii

  • Kapi'olani Medical Center for Women and Children, University of Hawaii - Honolulu

Massachusetts

  • DFCI, Massachusetts General Hospital - Boston

Michigan

  • Karmanos Cancer Institute, Children's Hospital of Michigan - Detroit

Trial Details

FieldValue
Enrollment Target 55 participants
Start Date 2008-10
Est. Completion 2013-11
Phase Phase 2

Sponsor

Medical College of Wisconsin

447 total trials

What the Registry Record Tells You About NCT00849147

The ClinicalTrials.gov registry entry for NCT00849147 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 55 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 200-participant average among 31 other Lymphoma, B-Cell trials with a reported enrollment target (72% lower). The listed sponsor is Medical College of Wisconsin, which has 447 total studies on file at ClinicalTrials.gov.

The record links to 6 conditions, with Lymphoma, B-Cell appearing as the primary indexed condition, and to 2 interventions - of which Haploidentical Bone Marrow Transplantation is the first listed.

NCT00849147 reports 17 study locations spanning 14 distinct geographic areas - top geographies include California, Maryland, Texas.

Frequently Asked Questions

What is clinical trial NCT00849147 about?

NCT00849147 is a clinical study titled "Bone Marrow Transplant From Partially Matched Donors and Nonmyeloablative Conditioning for Blood Cancers (BMT CTN 0603)". Bone marrow transplants are one treatment option for people with leukemia or lymphoma. Family members or unrelated donors with a similar type of bone marrow usually donate their bone marrow to the transplant patients. This study will evaluate the effectiveness of a new type of bone marrow transplant...

What is the current status of trial NCT00849147?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 55 participants. The study started on 2008-10. Estimated completion is 2013-11.

What conditions does trial NCT00849147 study?

This clinical trial studies the following conditions: Lymphoma, B-Cell, Leukemia, Myeloid, Acute, Burkitt Lymphoma, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Follicular.

What interventions are being tested in trial NCT00849147?

The interventions under investigation include: Haploidentical Bone Marrow Transplantation (BIOLOGICAL), GVHD prophylaxis (BIOLOGICAL).

Who is sponsoring clinical trial NCT00849147?

This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00849147 being conducted?

This trial has 17 study locations across California, Florida, Georgia, Hawaii, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.