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NCT03377543 · ClinicalTrials.gov registry record · Early Phase 1
Sleep and Inflammatory Resolution Pathway
A Early Phase 1 study of Sleep and Inflammation, sponsored by Beth Israel Deaconess Medical Center.
- Active
- Registry status
- Early Phase 1
- Development phase
- 66
- Enrollment target
- 1
- Study location
NCT03377543: Active Early Phase 1 study of Sleep and Inflammation, sponsored by Beth Israel Deaconess Medical Center.
NCT03377543 is a Early Phase 1 study of Sleep and Inflammation that is active but no longer recruiting, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 66 participants, below the 4,166-participant average among 151 other Sleep trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03377543, a Early Phase 1 study of Sleep and Inflammation, is active but no longer recruiting, sponsored by Beth Israel Deaconess Medical Center.
- ACTIVE NOT RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 66 participants
- Enrollment target
- 1
- Study location
Study Summary
Goal of this project is to investigate whether increases in inflammation that result from common patterns of restricting sleep on week nights and catching up on sleep over the weekend are caused by disruption in the newly discovered inflammatory resolution pathways. These pathways are crucial in the active termination of the inflammatory response, and their disruption may contribute to ongoing unresolved inflammation, which has been observed not only during periods of sleep restriction, but also after recovery sleep has been obtained. If the hypothesis is true, it is possible that increasing the body's natural production of endogenous, inflammatory resolution mediators may provide a non-behavioral strategy to limit the inflammatory consequences in those undergoing periods of sleep restriction with intermittent recovery sleep.
Primary Outcome
Resolvins
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Aspirin
Study Locations (1)
Massachusetts
- Beth Israel Deaconess Medical Center - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 66 participants |
| Start Date | 2018-06-06 |
| Est. Completion | 2025-12-30 |
| Phase | Early Phase 1 |
What the registry record for NCT03377543 still lists
NCT03377543 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 66 participants, a relatively small participant target, below the 4,166-participant average among 151 other Sleep trials with a reported enrollment target (98% lower).
The record links to 4 conditions, with Sleep appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT03377543 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT03377543 about?
NCT03377543 is a clinical study titled "Sleep and Inflammatory Resolution Pathway". Goal of this project is to investigate whether increases in inflammation that result from common patterns of restricting sleep on week nights and catching up on sleep over the weekend are caused by disruption in the newly discovered inflammatory resolution pathways. These pathways are crucial in the...
What is the current status of trial NCT03377543?
This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 66 participants. The study started on 2018-06-06. Estimated completion is 2025-12-30.
What conditions does trial NCT03377543 study?
This clinical trial studies the following conditions: Sleep, Inflammation, Inflammatory Response, Sleep Restriction.
What interventions are being tested in trial NCT03377543?
The interventions under investigation include: Placebo (DRUG), Aspirin (DRUG).
Who is sponsoring clinical trial NCT03377543?
This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03377543 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sleep
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03377543's enrollment target sits among peer trials
66 85th of 151 higher than 65 of 151 other Sleep trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sleep trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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