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NCT03377543 · ClinicalTrials.gov registry record · Early Phase 1
Sleep and Inflammatory Resolution Pathway
A Early Phase 1 study of Sleep and Inflammation, sponsored by Beth Israel Deaconess Medical Center.
- Active
- Registry status
- Early Phase 1
- Development phase
- 66
- Enrollment target
- 1
- Study location
NCT03377543 is a Early Phase 1 study of Sleep and Inflammation that is active but no longer recruiting, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 66 participants, below the 4,166-participant average among 151 other Sleep trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.
The verdict
NCT03377543, a Early Phase 1 study of Sleep and Inflammation, is active but no longer recruiting, sponsored by Beth Israel Deaconess Medical Center.
- ACTIVE NOT RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 66 participants
- Enrollment target
- 1
- Study location
Study Summary
Goal of this project is to investigate whether increases in inflammation that result from common patterns of restricting sleep on week nights and catching up on sleep over the weekend are caused by disruption in the newly discovered inflammatory resolution pathways. These pathways are crucial in the active termination of the inflammatory response, and their disruption may contribute to ongoing unresolved inflammation, which has been observed not only during periods of sleep restriction, but also after recovery sleep has been obtained. If the hypothesis is true, it is possible that increasing the body's natural production of endogenous, inflammatory resolution mediators may provide a non-behavioral strategy to limit the inflammatory consequences in those undergoing periods of sleep restriction with intermittent recovery sleep.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Aspirin
Study Locations (1)
Massachusetts
- Beth Israel Deaconess Medical Center - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 66 participants |
| Start Date | 2018-06-06 |
| Est. Completion | 2025-12-30 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03377543
The ClinicalTrials.gov registry entry for NCT03377543 describes a study currently listed as active not recruiting, categorized as Early Phase 1. The registered enrollment target is 66 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,166-participant average among 151 other Sleep trials with a reported enrollment target (98% lower). The listed sponsor is Beth Israel Deaconess Medical Center, which has 488 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Sleep appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT03377543 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT03377543 about?
NCT03377543 is a clinical study titled "Sleep and Inflammatory Resolution Pathway". Goal of this project is to investigate whether increases in inflammation that result from common patterns of restricting sleep on week nights and catching up on sleep over the weekend are caused by disruption in the newly discovered inflammatory resolution pathways. These pathways are crucial in the...
What is the current status of trial NCT03377543?
This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 66 participants. The study started on 2018-06-06. Estimated completion is 2025-12-30.
What conditions does trial NCT03377543 study?
This clinical trial studies the following conditions: Sleep, Inflammation, Inflammatory Response, Sleep Restriction.
What interventions are being tested in trial NCT03377543?
The interventions under investigation include: Placebo (DRUG), Aspirin (DRUG).
Who is sponsoring clinical trial NCT03377543?
This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03377543 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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