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NCT06159543 · ClinicalTrials.gov registry record · NA
The Effects of Fresh Mango Consumption on Cardiometabolic Outcomes in Free-living Individuals With Prediabetes
A NA study of Inflammation and Insulin Resistance, sponsored by Loma Linda University.
- Active
- Registry status
- NA
- Development phase
- 31
- Enrollment target
- 1
- Study location
NCT06159543: Active NA study of Inflammation and Insulin Resistance, sponsored by Loma Linda University.
NCT06159543 is a NA study of Inflammation and Insulin Resistance that is active but no longer recruiting, run by Loma Linda University. The registered enrollment target is 31 participants, below the 288-participant average among 132 other Inflammation trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06159543, a NA study of Inflammation and Insulin Resistance, is active but no longer recruiting, sponsored by Loma Linda University.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 31 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to test the effect of 12 weeks of 1.5 cups per day of fresh mango on glucose control, insulin resistance, lipids, inflammation, oxidation and body composition in individuals with prediabetes. The main questions it aims to answer are: * What is the effect of 1.5 cups per day of fresh mango over 12 weeks on indicators of glycemic control including fasting glucose and HgbA1c? * What is the effect of 1.5 cups per day of fresh mango over 12 weeks on fasting blood insulin and insulin resistance (HOMA-IR)? * What is the effect of 1.5 cups per day of fresh mango over 12 weeks on lipids including LDL-cholesterol, total cholesterol, HDL-cholesterol and triglycerides? * What is the effect of 1.5 cups per day of fresh mango over 12 weeks on oxidative stress including oxidized LDL-cholesterol and 8-iso-PGF2-alpha? * What is the effect of 1.5 cups per day of fresh mango over 12 weeks on markers of inflammation including c-reactive protein, e-selectin, ICAM, VCAM, TNF-alpha and IL-beta? * What is the effect of 1.5 cups per day of fresh mango over 12 weeks on percent body fat, fat mass, and lean mass? Participants will be asked to: * Consume 1.5 cups of mango per day for 12 weeks, take a 4 to 8 week break, and then avoid consuming mangos for 12 weeks * Attend a prerandomization clinic prior to study * Attend three (3) clinics where blood will be drawn during weeks 0, and 12 of the first phase and last week of the second phase of the study * Attend eight (8) clinics where anthropometric measurements (height, weight, body composition) will be conducted and interaction with study clinicians will occur during weeks 0, 4, 8, 12 of each phase of the study * Complete questionnaires and surveys in person and remotely, including six (6) 24-hour dietary recalls. Researchers will compare the 12 weeks participants consume mango to the 12 weeks the participants are not consuming mango to see if there are differences in glycemic indicators, insulin resistan
Conditions Studied
Interventions
- BEHAVIORAL Mango
Study Locations (1)
California
- Nutrition Research Center, School of Public Health, Loma Linda University - Loma Linda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 31 participants |
| Start Date | 2024-07-30 |
| Est. Completion | 2026-07 |
| Phase | NA |
What the registry record for NCT06159543 still lists
NCT06159543 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 288-participant average among 132 other Inflammation trials with a reported enrollment target (89% lower).
The record links to 5 conditions, with Inflammation appearing as the primary indexed condition, and to 1 intervention - of which Mango is the first listed.
NCT06159543 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06159543 about?
NCT06159543 is a clinical study titled "The Effects of Fresh Mango Consumption on Cardiometabolic Outcomes in Free-living Individuals With Prediabetes". The goal of this clinical trial is to test the effect of 12 weeks of 1.5 cups per day of fresh mango on glucose control, insulin resistance, lipids, inflammation, oxidation and body composition in individuals with prediabetes. The main questions it aims to answer are: * What is the effect of 1.5 cu...
What is the current status of trial NCT06159543?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 31 participants. The study started on 2024-07-30. Estimated completion is 2026-07.
What conditions does trial NCT06159543 study?
This clinical trial studies the following conditions: Inflammation, Insulin Resistance, Hyperglycemia, Oxidative Stress, Dyslipidemias.
What interventions are being tested in trial NCT06159543?
The interventions under investigation include: Mango (BEHAVIORAL).
Who is sponsoring clinical trial NCT06159543?
This trial is sponsored by Loma Linda University, which has 237 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06159543 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Where NCT06159543's enrollment target sits among peer trials
31 97th of 132 higher than 36 of 132 other Inflammation trials
participants (enrollment target), bucketed by value
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