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Hypertension: full-pipeline trial registry
152 of 472 indexed Hypertension trials are currently recruiting.
Corpus placement: #8 of 28,707 conditions by registered trial count.
472 US clinical trials · 152 currently recruiting · #8 of 28,707 conditions by registered trial count
Hypertension: 472 US clinical trials tracked, 152 recruiting.
Hypertension is the subject of 472 registered US clinical trials on ClinicalTrials.gov, 152 of them currently open to new participants. 65 are in Phase 3-4 (later-stage) and 64 in Phase 1-2 (earlier-stage). The most active sponsor is Johns Hopkins University, running 15 of these trials.
Enrollment posture brief
Registry condition hypertension
OPEN 152 | RECR 32% | LATE 65 | EARLY 64 | RANK #8 | SPON 15
Volume-matched condition peers
Nearest open-share peer: Leukemia, Myeloid, Acute (32% recruiting · 31 trials)
Hypertension lists 152 open slots (32% of 472 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Hypertension on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Hypertension is recruiting below its size-band peers.
152 of 472 indexed trials (32.2%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Hypertension trials is spread across many organizations.
Johns Hopkins University accounts for 15 of 472 trials (3.2%). 195 distinct sponsors appear on at least one study for this condition label.
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Typical Hypertension enrolment sits around 168 participants.
Median target enrolment is 168 among the 471 trials that report a genuine target (sentinel values excluded). 170 of those (36.1%) plan for fewer than 100 participants.
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Hypertension research is mostly interventional.
407 interventional and 65 observational studies make up this index (86.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
472 total, page 9 of 10
The Effect of CS-3150 Exposure on Corrected QT (QTc) Interval Duration in Healthy Volunteers
Daiichi Sankyo
NCT04019652
A Study Investigating the Bioequivalence of the Fixed Dose Combination of COREG CR to COREG CR and ZESTRIL.
GlaxoSmithKline
NCT00552708
The Antihypertensives and Vascular, Endothelial and Cognitive Function Trial
University of Southern California
NCT00605072
24-Hour Ambulatory Blood Pressure Monitoring in Community Pharmacies
Virginia Commonwealth University
NCT03920956
Heart Inflammation and Mental Stress Study
University of Miami
NCT03695146
Grocery Prescription Program for Medicaid Adults With Hypertension or Type 2 Diabetes
Alison Gustafson
NCT06033664
Effectiveness of Prazosin on the Urinary Sodium Excretion Response to Mental Stress
Augusta University
NCT02431936
Study to Demonstrate the Bioequivalence of the Fixed Dose Combination of COREG CR™ and Lisinopril to Its Components
GlaxoSmithKline
NCT00556920
Effects of Use of a Connected Pillbox On Medication Adherence
University of Pennsylvania
NCT02593032
Mechanisms of Intradialytic Hypertension
Emory University
NCT01947673
Febuxostat, Blood Pressure and the Intrarenal Renin-Angiotensin System (RAS)
Paul N. Hopkins
NCT01328769
Sodium Nitroprusside for Blood Pressure Reduction in the ICU (SNP2)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00621816
Nebivolol and Endothelial Regulation of Fibrinolysis (NERF)
University of Colorado, Boulder
NCT01595516
Conditioned Pharmacotherapeutic Effects in Hypertension
University of Rochester
NCT02056626
Developing an Adaptive Lifestyle Intervention Program in Family Medicine Clinics
University of Alabama at Birmingham
NCT04392284
A Pilot Study of Changing Medication Adherence In Hypertensive African-American Patients
Weill Medical College of Cornell University
NCT00248937
Effect of Electrical Stimulation at Acupoints on Blood Pressure
Logan College of Chiropractic
NCT00459758
Nutraceutical Supplement in the Management of Hypertension
Thorne HealthTech
NCT02663479
Bioequivalency Study of Amlodipine Tablets Under Fasting Conditions
Roxane Laboratories
NCT00602017
Examining the Individual Response to a Restricted Sodium Diet in Hypertensive Patients
The University of Texas Health Science Center at San Antonio
NCT04764253
A Study to Evaluate the Safety/Tolerability and Pharmacokinetics of Aliskiren in Hypertensive Pediatric and Adolescent Patients 6-17 Years of Age
Novartis
NCT00834041
Bioequivalency Study of Ramipril 10 mg Capsules Under Fed Conditions
Roxane Laboratories
NCT00702260
Brain Connections and Blood Pressure
Ohio State University
NCT03736434
Medication Adherence in Hypertensive Individuals With Bipolar Disorder
Case Western Reserve University
NCT02983877
Nebivolol Versus Metoprolol: Comparative Effects on Fatigue and Quality of Life
Weill Medical College of Cornell University
NCT00999102
Clevidipine in the Treatment of Patients With Acute Hypertension and Intracerebral Hemorrhage (ACCELERATE)
The Medicines Company
NCT00666328
12 Weeks of Resistance Band Exercise Impacts on Metabolic Syndrome Progression in Postmenopausal Women
Pusan National University
NCT04014686
Promoting Medication Adherence Among Older Adults With Hypertension
Tulane University School of Medicine
NCT02846220
Pathophysiology of Cardiometabolic Risk Factors in African Americans
Vanderbilt University Medical Center
NCT01122407
Tailored Home-Based Exercise Program for Multiple Chronic Conditions
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT03874754
Effects of a 4-week Raw, Plant-based Diet on Anthropometric and Cardiovascular Risk Factors
Texas Woman's University
NCT03134235
A Mobile Health (mHealth) Strategy for Improving Blood Pressure Control Among Adult Hypertensive African Americans
University of Chicago
NCT06078540
Cardioprotective Benefits of Carvedilol-CR or Valsartan Added to Lisinopril
State University of New York at Buffalo
NCT00657241
Using Nonpharmacological Approaches in Hypertension Prevention and Management
Kansas State University
NCT06490575
Water-only Fasting in the Treatment of Hypertension Patients
TrueNorth Health Foundation
NCT04515095
Peripheral Nerve Blocks for Above-the-knee Amputations
University of Florida
NCT03404180
Sodium Watchers Program - Hypertension
Misook L. Chung
NCT04076280
Ambulatory vs Office BP Management Usual Care for Diagnosing and Managing Hypertension: A Pilot Study
Anthony J Viera, MD, MPH
NCT02121041
Blood Pressure First Medication Therapy Management
American Pharmacists Association Foundation
NCT04275934
NUTRITION MATTERS: A Food is Medicine Intervention for African-American Adults With Multiple Chronic Conditions
Winston Salem State University
NCT06933940
Bioequivalency Study of Losartan Potassium/Hydrochlorothiazide 100 mg /25 mg Tablet Under Fed Conditions
Roxane Laboratories
NCT01102465
Reducing Disparities in the Treatment of Hypertension Using the OWL mHealth Tool
Paula Gardiner
NCT03974334
Cardiovascular Precision Medicine & Remote Intervention
Icahn School of Medicine at Mount Sinai
NCT05814562
Olmesartan Pediatric Pharmacokinetic (PK) Study
Daiichi Sankyo
NCT00151814
Monitoring Subjects With Fluid-Management Issues In the Home Environment
Baxter Healthcare Corporation
NCT02190877
Effects of Quinapril 40 mg With Alpha Lipoic Acid or Placebo on Diabetes and Hypertension
InVasc Therapeutics
NCT00795262
The Effects of Pumpkin Seed Oil Supplementation on Cardiovascular Function in Postmenopausal Women.
Marymount University
NCT03716960
Pilot to Examine Risk and Feasibility of Remote Management of BP From Childhood Into Early Adulthood
University of California, San Francisco
NCT03691701
Gut Butyrate and Blood Pressure in African Americans
University of North Carolina, Chapel Hill
NCT04415333
Phase 1 PK Study to Evaluate the PK of CIN-107 in Subjects With Hepatic Impairment
AstraZeneca
NCT05961397
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 39 |
| Phase 2 | 25 |
| Phase 3 | 37 |
| Phase 4 | 28 |
Top Sponsors
Named interventions
Most-linked intervention names on Hypertension records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Hypertension trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Hypertension page
472 registered trials, 152 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 152 Hypertension trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Johns Hopkins University sponsors the most Hypertension trials on record, review their full trial history before evaluating a specific study. See Johns Hopkins University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Hypertension condition card totals 472 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.