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COMPLETED Phase 3

Clevidipine in the Treatment of Patients With Acute Hypertension and Intracerebral Hemorrhage (ACCELERATE)

NCT00666328 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study was to determine the efficacy and safety of clevidipine for treating acute hypertension (high blood pressure, defined as systolic blood pressure \>160 mmHg) in patients with intracerebral hemorrhage (i.e., bleeding in the brain; stroke).

Conditions Studied

Interventions

  • DRUG clevidipine

Study Locations (17)

North Carolina

  • Duke University Medical Center — Durham
  • Guilford Neurologic - Moses H Cone Health System — Greensboro

Ohio

  • Cleveland Clinic Hospitals — Cleveland
  • The Ohio State University — Columbus

Other

  • Universitatsklinikum Erlangen — Erlangen
  • Universitatsklinikum Heidelberg — Heidelberg

District of Columbia

  • Washington Hospital Center — Washington D.C.

Hawaii

  • The Queens Medical Center — Honolulu

Maryland

  • The John Hopkins Hospital — Baltimore

Massachusetts

  • Maine Medical Center — Portland

Michigan

  • Henry Ford Hospital — Detroit

Trial Details

FieldValue
Enrollment Target 37 participants
Start Date 2008-06
Est. Completion 2010-04
Phase Phase 3

Sponsor

The Medicines Company

5 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00666328

The ClinicalTrials.gov registry entry for NCT00666328 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 37 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is The Medicines Company, which has 5 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Hypertension appearing as the primary indexed condition, and to 1 intervention — of which clevidipine is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00666328 reports 17 study locations spanning 14 distinct geographic areas — top geographies include North Carolina, Ohio, Other. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00666328 about?

NCT00666328 is a clinical study titled "Clevidipine in the Treatment of Patients With Acute Hypertension and Intracerebral Hemorrhage (ACCELERATE)". The purpose of this study was to determine the efficacy and safety of clevidipine for treating acute hypertension (high blood pressure, defined as systolic blood pressure \>160 mmHg) in patients with intracerebral hemorrhage (i.e., bleeding in the brain; stroke).

What is the current status of trial NCT00666328?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 37 participants. The study started on 2008-06. Estimated completion is 2010-04.

What conditions does trial NCT00666328 study?

This clinical trial studies the following conditions: Hypertension, Hemorrhage. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00666328?

The interventions under investigation include: clevidipine (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00666328?

This trial is sponsored by The Medicines Company, which has 5 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00666328 being conducted?

This trial has 17 study locations across District of Columbia, Hawaii, Maryland, Massachusetts, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial