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NCT00621816 · ClinicalTrials.gov registry record · Phase 2

Sodium Nitroprusside for Blood Pressure Reduction in the ICU (SNP2)

A Phase 2 study of Hypertension, sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

Completed
Registry status
Phase 2
Development phase
45
Enrollment target
8
Study locations

NCT00621816 is a Phase 2 study of Hypertension that has completed, run by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The registered enrollment target is 45 participants, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (99% lower). The trial reports 8 study locations across 6 states.

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The verdict

NCT00621816, a Phase 2 study of Hypertension, has completed, sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

COMPLETED
Registry status
Phase 2
Development phase
45 participants
Enrollment target
8
Study locations

Study Summary

Nitroprusside is used commonly in the Intensive Care Unit for long periods of time in order to reduce blood pressure. It is not known if the body compensates over time to the blood pressure lowering, and if when the nitroprusside is stopped the blood pressure goes up at a faster rate and is higher than it was at the start of the treatment. This study will answer these questions.

Conditions Studied

Interventions

  • DRUG nitroprusside
  • DRUG placebo infusion

Study Locations (8)

North Carolina

  • University of North Carolina - Chapel Hill - Chapel Hill
  • Duke University Medical Center - Durham
  • Duke University Medical Center - Durham

Arkansas

  • Arkansas Children's Hospital - Little Rock

California

  • Stanford University School of Medicine - Stanford

Kentucky

  • Kosair Charities Pediatric Clinical Research Unit - Louisville

Michigan

  • University of Michigan - Mott Children's Hospital - Ann Arbor

West Virginia

  • West Virginia University - Morgantown

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 2009-01
Est. Completion 2011-01
Phase Phase 2

What the Registry Record Tells You About NCT00621816

The ClinicalTrials.gov registry entry for NCT00621816 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (99% lower). The listed sponsor is Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), which has 305 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Hypertension appearing as the primary indexed condition, and to 2 interventions - of which nitroprusside is the first listed.

NCT00621816 reports 8 study locations spanning 6 distinct geographic areas - top geographies include North Carolina, Arkansas, California.

Frequently Asked Questions

What is clinical trial NCT00621816 about?

NCT00621816 is a clinical study titled "Sodium Nitroprusside for Blood Pressure Reduction in the ICU (SNP2)". Nitroprusside is used commonly in the Intensive Care Unit for long periods of time in order to reduce blood pressure. It is not known if the body compensates over time to the blood pressure lowering, and if when the nitroprusside is stopped the blood pressure goes up at a faster rate and is higher t...

What is the current status of trial NCT00621816?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 45 participants. The study started on 2009-01. Estimated completion is 2011-01.

What conditions does trial NCT00621816 study?

This clinical trial studies the following conditions: Hypertension.

What interventions are being tested in trial NCT00621816?

The interventions under investigation include: nitroprusside (DRUG), placebo infusion (DRUG).

Who is sponsoring clinical trial NCT00621816?

This trial is sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), which has 305 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00621816 being conducted?

This trial has 8 study locations across Arkansas, California, Kentucky, Michigan, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.