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NCT04278404 · ClinicalTrials.gov registry record
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
A clinical trial of Hypertension and Heart Failure, sponsored by Duke University.
- Recruiting
- Registry status
- 5,000
- Enrollment target
- 20
- Study locations
NCT04278404 is a study of Hypertension and Heart Failure that is actively recruiting participants, run by Duke University. The registered enrollment target is 5,000 participants, above the 3,497-participant average among 470 other Hypertension trials with a reported enrollment target (43% higher). The trial reports 20 study locations across 15 states.
The verdict
NCT04278404, a study of Hypertension and Heart Failure, is actively recruiting participants, sponsored by Duke University.
- RECRUITING
- Registry status
- 5,000 participants
- Enrollment target
- 20
- Study locations
Study Summary
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK of understudied drugs currently being administered to children per SOC as prescribed by their treating provider.
Conditions Studied
Interventions
- DRUG The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:
Study Locations (20)
California
- University of California, Los Angeles Medical Center - Los Angeles
- Lucile Packard Children's Hospital - Palo Alto
Colorado
- Colorado University Denver - Aurora
- The Children's Hospital Colorado - Aurora
Illinois
- Ann and Robert H. Lurie Childrens Hospital of Chicago - Chicago
- Ann and Robert H. Lurie Childrens Hospital of Chicago - Chicago
Louisiana
- Tulane University Health Science Center - New Orleans
- Ochsner Baptist Clinical Trials Unit - New Orleans
Massachusetts
- Boston Children's Hospital - Boston
- Massachusetts General Hospital - Lexington
Arizona
- Phoenix Children's Hospital - Phoenix
Arkansas
- Arkansas Children's Hospital Research Institute - Little Rock
Delaware
- Alfred I. DuPont Hospital for Children - Wilmington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5,000 participants |
| Start Date | 2020-03-05 |
| Est. Completion | 2027-09 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04278404
The ClinicalTrials.gov registry entry for NCT04278404 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 5,000 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 3,497-participant average among 470 other Hypertension trials with a reported enrollment target (43% higher). The listed sponsor is Duke University, which has 1,725 total studies on file at ClinicalTrials.gov.
The record links to 10 conditions, with Hypertension appearing as the primary indexed condition, and to 1 intervention - of which The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care: is the first listed.
NCT04278404 reports 20 study locations spanning 15 distinct geographic areas - top geographies include California, Colorado, Illinois.
Frequently Asked Questions
What is clinical trial NCT04278404 about?
NCT04278404 is a clinical study titled "Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)". The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK ...
What is the current status of trial NCT04278404?
This trial is currently recruiting. The enrollment target is 5,000 participants. The study started on 2020-03-05. Estimated completion is 2027-09.
What conditions does trial NCT04278404 study?
This clinical trial studies the following conditions: Hypertension, Heart Failure, Pain, Pulmonary Arterial Hypertension, Edema.
What interventions are being tested in trial NCT04278404?
The interventions under investigation include: The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care: (DRUG).
Who is sponsoring clinical trial NCT04278404?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04278404 being conducted?
This trial has 20 study locations across Arizona, Arkansas, California, Colorado, Delaware. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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