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NCT06778239 · ClinicalTrials.gov registry record
Childhood-Onset Essential Hypertension Natural History Study
A clinical trial of Hypertension and Essential Hypertension, sponsored by National Human Genome Research Institute (NHGRI).
- Recruiting
- Registry status
- 2,300
- Enrollment target
- 1
- Study location
NCT06778239 is a study of Hypertension and Essential Hypertension that is actively recruiting participants, run by National Human Genome Research Institute (NHGRI). The registered enrollment target is 2,300 participants, below the 3,502-participant average among 470 other Hypertension trials with a reported enrollment target (34% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06778239, a study of Hypertension and Essential Hypertension, is actively recruiting participants, sponsored by National Human Genome Research Institute (NHGRI).
- RECRUITING
- Registry status
- 2,300 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: Childhood-onset essential hypertension (COEH) is high blood pressure that develops in children and teens. High blood pressure is a major risk factor for heart disease. COEH is more likely to be caused by changes in genes rather than by factors like stress or diet. Researchers want to learn more about how changes in genes relate to COEH. They hope to use that information to develop better treatments for children with high blood pressure. Objective: This natural history study will look for genes and gene changes that may lead to COEH. Eligibility: People aged 2 years and older with COEH or who had COEH when they were children. Healthy relatives of those with COEH are also needed. Design: Participants will have one clinic visit per year for up to 10 years. All participants will have a physical exam. They will provide samples of blood and urine. At their first visit, they will have a swab (like a Q-tip) rubbed between their gums and cheeks. They may agree to having a skin biopsy; a piece of skin about the size of a pencil eraser will be removed. Affected participants aged 2 to 17 years old will have additional tests: * They will have sensors placed on their skin to look at their blood vessels and see how blood is moving in their bodies. * They will lie or stand while a machine measures the amount of fat and muscle in their bodies. * They will have an ultrasound; a wand will be rubbed against their skin to take pictures of their kidneys. Other things are optional for all participants: * They may have photographs taken of their bodies. * They may have tests of their heart function. * They may have different types of imaging scans.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,300 participants |
| Start Date | 2025-05-30 |
| Est. Completion | 2034-12-09 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06778239
The ClinicalTrials.gov registry entry for NCT06778239 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 2,300 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,502-participant average among 470 other Hypertension trials with a reported enrollment target (34% lower). The listed sponsor is National Human Genome Research Institute (NHGRI), which has 185 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Hypertension appearing as the primary indexed condition, and to 0 interventions.
NCT06778239 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT06778239 about?
NCT06778239 is a clinical study titled "Childhood-Onset Essential Hypertension Natural History Study". Background: Childhood-onset essential hypertension (COEH) is high blood pressure that develops in children and teens. High blood pressure is a major risk factor for heart disease. COEH is more likely to be caused by changes in genes rather than by factors like stress or diet. Researchers want to le...
What is the current status of trial NCT06778239?
This trial is currently recruiting. The enrollment target is 2,300 participants. The study started on 2025-05-30. Estimated completion is 2034-12-09.
What conditions does trial NCT06778239 study?
This clinical trial studies the following conditions: Hypertension, Essential Hypertension.
Who is sponsoring clinical trial NCT06778239?
This trial is sponsored by National Human Genome Research Institute (NHGRI), which has 185 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06778239 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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