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NCT05615636 · ClinicalTrials.gov registry record · Phase 2

A Phase II Trial of Mosunetuzumab, Polatuzumab, Tafasitamab, and Lenalidomide in Patients With Relapsed B-cell NHL

A Phase 2 study of Hodgkin Lymphoma and B-cell Lymphoma, sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
Phase 2
Development phase
36
Enrollment target
1
Study location

NCT05615636: Recruiting Phase 2 study of Hodgkin Lymphoma and B-cell Lymphoma, sponsored by M.D. Anderson Cancer Center.

NCT05615636 is a Phase 2 study of Hodgkin Lymphoma and B-cell Lymphoma that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 36 participants, below the 165-participant average among 71 other Hodgkin Lymphoma trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05615636, a Phase 2 study of Hodgkin Lymphoma and B-cell Lymphoma, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
Phase 2
Development phase
36 participants
Enrollment target
1
Study location

Study Summary

To learn if giving mosunetuzumab in combination with polatuzumab vedotin, tafasitamab, and lenalidomide can help to control relapsed/refractory FL and DLBCL.

Interventions

  • DRUG Mosunetuzumab
  • DRUG Lenalidomide
  • DRUG Polatuzumab vedotin
  • DRUG Tafasitamab

Study Locations (1)

Texas

  • M D Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2023-04-28
Est. Completion 2027-08-19
Phase Phase 2
M.D. Anderson Cancer Center

2,692 total trials

What NCT05615636 shows while recruiting

NCT05615636 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 165-participant average among 71 other Hodgkin Lymphoma trials with a reported enrollment target (78% lower).

The record links to 3 conditions, with Hodgkin Lymphoma appearing as the primary indexed condition, and to 4 interventions - of which Mosunetuzumab is the first listed.

NCT05615636 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT05615636 about?

NCT05615636 is a clinical study titled "A Phase II Trial of Mosunetuzumab, Polatuzumab, Tafasitamab, and Lenalidomide in Patients With Relapsed B-cell NHL". To learn if giving mosunetuzumab in combination with polatuzumab vedotin, tafasitamab, and lenalidomide can help to control relapsed/refractory FL and DLBCL.

What is the current status of trial NCT05615636?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 36 participants. The study started on 2023-04-28. Estimated completion is 2027-08-19.

What conditions does trial NCT05615636 study?

This clinical trial studies the following conditions: Hodgkin Lymphoma, B-cell Lymphoma, Relapsed B-cell NHL.

What interventions are being tested in trial NCT05615636?

The interventions under investigation include: Mosunetuzumab (DRUG), Lenalidomide (DRUG), Polatuzumab vedotin (DRUG), Tafasitamab (DRUG).

Who is sponsoring clinical trial NCT05615636?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05615636 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Hodgkin Lymphoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05615636's enrollment target sits among peer trials

36 43rd of 71 higher than 28 of 71 other Hodgkin Lymphoma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Hodgkin Lymphoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

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Source: ClinicalTrials.gov NCT05615636, the US trial registry maintained by the National Library of Medicine. NCT05615636 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.