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A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer
NCT06521567 · View on ClinicalTrials.gov ↗
Study Summary
The goal of this interventional study is to determine the strength of cobolimab and dostarlimab that is most tolerated in children and young adults who have advanced solid tumors. This study also aims: (a) to check if it is safe to use cobolimab and dostarlimab combination in children and young adults, (b) to see how to manage the side effects that may occur, and (c) the effect of this treatment in participants
Conditions Studied
Interventions
- DRUG Dostarlimab
- DRUG Cobolimab
Study Locations (20)
Other
- GSK Investigational Site — Brno
- GSK Investigational Site — Phaha 5
- GSK Investigational Site — Copenhagen
- GSK Investigational Site — Bordeaux
- GSK Investigational Site — Lyon
- GSK Investigational Site — Paris
- GSK Investigational Site — Strasbourg
- GSK Investigational Site — Villejuif
- GSK Investigational Site — Bologna
- GSK Investigational Site — Naples
- GSK Investigational Site — Barcelona
- GSK Investigational Site — Madrid
- GSK Investigational Site — Madrid
- GSK Investigational Site — Valencia
California
- GSK Investigational Site — Los Angeles
Iowa
- GSK Investigational Site — Iowa City
New Jersey
- GSK Investigational Site — Hackensack
Ohio
- GSK Investigational Site — Cincinnati
Rhode Island
- GSK Investigational Site — Providence
Wisconsin
- GSK Investigational Site — Madison
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 83 participants |
| Start Date | 2025-03-06 |
| Est. Completion | 2026-10-13 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06521567
The ClinicalTrials.gov registry entry for NCT06521567 describes a study currently listed as active not recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 83 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is GlaxoSmithKline, which has 558 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 10 conditions, with Melanoma appearing as the primary indexed condition, and to 2 interventions — of which Dostarlimab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06521567 reports 20 study locations spanning 7 distinct geographic areas — top geographies include Other, California, Iowa. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06521567 about?
NCT06521567 is a clinical study titled "A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer". The goal of this interventional study is to determine the strength of cobolimab and dostarlimab that is most tolerated in children and young adults who have advanced solid tumors. This study also aims: (a) to check if it is safe to use cobolimab and dostarlimab combination in children and young adul...
What is the current status of trial NCT06521567?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 83 participants. The study started on 2025-03-06. Estimated completion is 2026-10-13.
What conditions does trial NCT06521567 study?
This clinical trial studies the following conditions: Melanoma, Hodgkin Lymphoma, Osteosarcoma, Ependymoma, Hepatocellular Carcinoma (HCC). These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06521567?
The interventions under investigation include: Dostarlimab (DRUG), Cobolimab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06521567?
This trial is sponsored by GlaxoSmithKline, which has 558 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06521567 being conducted?
This trial has 20 study locations across California, Iowa, New Jersey, Ohio, Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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