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ClinicalTrials.gov 28 recruiting now early-phase tilt

Hodgkin Lymphoma: early-phase trial registry

28 of 72 indexed Hodgkin Lymphoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #191 of 28,707 conditions by registered trial count.

72 US clinical trials · 28 currently recruiting · #191 of 28,707 conditions by registered trial count

Hodgkin Lymphoma: 72 US clinical trials tracked, 28 recruiting.

Hodgkin Lymphoma is the subject of 72 registered US clinical trials on ClinicalTrials.gov, 28 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 58 in Phase 1-2 (earlier-stage). The most active sponsor is St. Jude Children's Research Hospital, running 7 of these trials.

Enrollment posture brief

Registry condition hodgkin-lymphoma

OPEN 28 | RECR 39% | LATE 1 | EARLY 58 | RANK #191 | SPON 7

Nearest open-share peer: Chronic Myeloid Leukemia (39% recruiting · 36 trials)

NSCLC66.7%Crohn Disease47.2%Chronic Low Back Pain41.7%Hodgkin Lymphoma (this)39%HIV-1-infection33.3%
Open-enrollment share among volume-matched conditions near Hodgkin Lymphoma

Hodgkin Lymphoma lists 28 open slots (39% of 72 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Hodgkin Lymphoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Hodgkin Lymphoma recruits in line with its size-band peers.

    28 of 72 indexed trials (38.9%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Hodgkin Lymphoma trials is spread across many organizations.

    St. Jude Children's Research Hospital accounts for 7 of 72 trials (9.7%). 46 distinct sponsors appear on at least one study for this condition label.

  3. Most Hodgkin Lymphoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 54 among the 72 trials that report a genuine target (sentinel values excluded). 52 of those (72.2%) plan for fewer than 100 participants.

  4. Hodgkin Lymphoma research is mostly interventional.

    67 interventional and 5 observational studies make up this index (93.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 126Phase 232Phase 31

Open and recent trials

72 total, page 2 of 2

ACTIVE NOT RECRUITING Phase 2 22 participants

Pembrolizumab and Involved Site Radiation Therapy for Early Stage Relapsed or Primary Refractory Hodgkin Lymphoma

Memorial Sloan Kettering Cancer Center

NCT03179917

ACTIVE NOT RECRUITING Phase 2 22 participants

Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy

Masonic Cancer Center, University of Minnesota

NCT03674411

ACTIVE NOT RECRUITING Phase 1 18 participants

Tumor Associated Antigen Specific T Cells (TAA-T) With PD1 Inhibitor for Lymphoma

Catherine Bollard

NCT03843294

ACTIVE NOT RECRUITING Phase 1 16 participants

Cytokine-Treated Veto Cells in Treating Patients With Hematologic Malignancies Following Stem Cell Transplant

M.D. Anderson Cancer Center

NCT03622788

ACTIVE NOT RECRUITING Phase 2 13 participants

Ipilimumab With or Without Nivolumab in Relapsed/Refractory cHL

Dana-Farber Cancer Institute

NCT04938232

ACTIVE NOT RECRUITING Phase 2 8 participants

Study of Magrolimab and Pembrolizumab in Relapsed or Refractory Classic Hodgkin Lymphoma

Stanford University

NCT04788043

ACTIVE NOT RECRUITING Phase 2 7 participants

Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantation

City of Hope Medical Center

NCT04060277

COMPLETED 1,340 participants

Genome Expression in Lymphoma, Leukemia and Multiple Myeloma

National Cancer Institute (NCI)

NCT00339963

COMPLETED Phase 1 320 participants

An Investigational Immuno-Therapy Study to Determine the Safety and Effectiveness of Nivolumab and Daratumumab in Patients With Multiple Myeloma

Bristol-Myers Squibb

NCT01592370

COMPLETED Phase 2 203 participants

A Study of Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Physician's Choice Chemotherapy in PD-(L)1-refractory, Relapsed or Refractory Classical Hodgkin Lymphoma (MK-4280A-008)

Merck Sharp & Dohme

NCT05508867

COMPLETED Phase 2 82 participants

Pembrolizumab After ASCT for Hodgkin Lymphoma, DLBCL and T-NHL

Dana-Farber Cancer Institute

NCT02362997

COMPLETED Phase 1 57 participants

Pralatrexate + Romidepsin in Relapsed/Refractory Lymphoid Malignancies

Jennifer Amengual

NCT01947140

COMPLETED Phase 2 40 participants

Brentuximab for Newly Diagnosed Hodgkin Disease

Mitchell Cairo

NCT02398240

COMPLETED NA 40 participants

Effects of Prebiotics on Gut Microbiome in Patients Undergoing HSCT

University of Virginia

NCT04629430

COMPLETED Phase 2 34 participants

Brentuximab Vedotin Plus AD in Non-bulky Limited Stage Hodgkin Lymphoma

Massachusetts General Hospital

NCT02505269

COMPLETED Early Phase 1 30 participants

Pilot Study of Non-Myeloablative, HLA-Matched Allogeneic Stem Cell Transplantation for Pediatric Hematopoietic Malignancies

National Cancer Institute (NCI)

NCT00013533

COMPLETED Phase 1 28 participants

A Study to Assess AFM13 in Patients With Hodgkin Lymphoma

Affimed

NCT01221571

COMPLETED Phase 1 23 participants

Safety Study of XmAb®2513 to Treat Hodgkin Lymphoma or Anaplastic Large Cell Lymphoma

Xencor

NCT00606645

COMPLETED Phase 2 22 participants

Total Body Irradiation +/- Total Lymphoid Irradiation & Anti-Thymocyte Globulin in Non-myeloablative Hematopoietic Cell Transplantation

Stanford University

NCT03734601

COMPLETED Phase 2 18 participants

CD8+ Memory T-Cells as Consolidative Therapy After Donor Non-myeloablative Hematopoietic Cell Transplant in Treating Patients With Leukemia or Lymphoma

Robert Lowsky

NCT02424968

COMPLETED Phase 1 14 participants

Duvelisib in Combination With BMS-986345 in Lymphoid Malignancy

H. Lee Moffitt Cancer Center and Research Institute

NCT05065866

COMPLETED Phase 1 14 participants

Targeted Marrow Irradiation, Fludarabine Phosphate, and Busulfan Before Donor Progenitor Cell Transplant in Treating Patients With Hematologic Malignancies

Case Comprehensive Cancer Center

NCT02129582

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Phase Distribution

PhaseTrial count
Phase 1 26
Phase 2 32
Phase 3 1

Named interventions

Most-linked intervention names on Hodgkin Lymphoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Cyclophosphamide Drug
8 trials
Dacarbazine Drug
5 trials
Nivolumab Drug
5 trials
Doxorubicin Drug
5 trials
Fludarabine Drug
5 trials
Pembrolizumab Drug
5 trials
Multi-peptide CMV-Modified Vaccinia Ankara Vaccine Biological
4 trials
Bleomycin Drug
3 trials

US sites by state

Facility locations filed on Hodgkin Lymphoma trials. A trial with sites in several states counts in each.

California 21 trials
New York 17 trials
Florida 15 trials
Texas 14 trials
Massachusetts 13 trials
Tennessee 10 trials
Illinois 10 trials
Ohio 8 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Hodgkin Lymphoma page

72 registered trials, 28 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Hodgkin Lymphoma condition card totals 72 registered trials; most-linked intervention Cyclophosphamide; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.